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IVD Trends to Watch: Breakthroughs in Histology and Cytology

Histology and cytology, foundational pillars of pathological labs, play a critical role in diagnosing a variety of diseases, including cancer. With innovations enhancing diagnostic accuracy, efficiency, and patient outcomes, the industry is poised for significant growth and transformation in the coming years. In the report, Histology and Cytology IVD Market Update, 2024, Kalorama Information’s research reveals that the $5.5 billion global histology IVD market grew almost 10% from 2022 to 2023. The market is projected to maintain a mid-single-digit compound annual growth rate (CAGR) through 2028.

Pathologists provide essential information about cells, tissues, and organs that guides physicians in treatment and prognosis. As technology advances, our understanding of the relationships between tissue structures and diseases has deepened, leading to significant improvements in accuracy and workflow automation.

Presently, histology and cytology are on the cusp of a technological revolution. Most notably, this is due to the advent of digital imaging, quantitative microscopy, precision microscopy, artificial intelligence, and virtual histology. Key innovations in histology and cytology include:

  • Multiplexing Reagents: Allowing multiple analytes to be detected in one test.
  • Quantitative Testing: Offering precise DNA copy level assessments.
  • Digital Imaging: Facilitating better resolution, consultation, and integration with Electronic Medical Records (EMR).

Likewise, new technologies like MediSCAPE, a 3D microscope for real-time tissue imaging, and AI-driven digital imaging are set to transform the field, potentially replacing conventional biopsies with in vivo imaging. These innovations are set to transform the field, offering enhanced diagnostic capabilities and streamlined processes that will take histology and cytology to the next level.

Histological analysis involves preanalytical sample preparation and advanced staining. Samples from sputum, cervical and synovial fluids, and biopsied tissues are processed, placed on glass slides, and stained to reveal cellular structures and morphology. Technologists perform an initial screen, followed by pathologists who investigate suspicious cells to detect cancer and infectious agents.

Pathologists use a range of techniques, including in situ hybridization (ISH), immunohistochemistry (IHC), immunofluorescence (IF), and molecular analysis, to improve cancer diagnosis. Automation of histology tests is becoming routine, especially in developed regions, and is gradually spreading to urban centers in developing countries.

The aforementioned developed regions benefiting from the automation of histology tests include North America and Europe, which combined account for almost three-quarters of global histology and cytology sales. Nevertheless, palpable activity in Asia-Pacific has Kalorama analysts excited about the market’s momentum in that region. Particularly, China’s growing histology/cytology market reflects efforts to enhance screening and care access.

For more insights, purchase Histology and Cytology IVD Market Update, 2024, today!