Description
This report, The World Liquid Biopsy Market, 2021, from Kalorama Information, contains up-to-date information and useful data points for business planning:
- Research vs. Clinical Liquid Biopsy
- The Market for Liquid Biopsy by Region
- The Market for Liquid Biopsy Market by Type of Analyte
- The Market for CTC-based Liquid Biopsy
- The Market for ctDNA-based Liquid Biopsy
- The Market for EV and Exosome-based Liquid Biopsy
- The Market for Multi-Analyte-based Liquid Biopsy
- The Market for Other Liquid Biopsy
- Liquid Biopsy Market by Type of Cancer (Breast, Lung, Colorectal, Ovarian, Prostate, Pan-Cancer, Other Cancer)
- Selected ctDNA-based Liquid Biopsy Tests in Development
- Selected Market-Available CTC-based Liquid Biopsy Tests, 2021
- Selected Liquid Biopsy Tests That Assess Multiple Analytes, 2021
While tissue biopsies and imaging techniques remain the current standards of care in the diagnosis of solid tumors, they have risks and limitations and limitations, some of which can be overcome by the use of liquid biopsy in clinical oncology, as an alternative or complementary technique to the current standards of care.
Liquid biopsy testing has many potential applications in aspects of clinical oncology, including:
- Early detection and diagnosis / screening
- Alternative testing method when tissue biopsy is difficult/impossible, or when the primary site of metastatic disease is unknown
- Therapy personalization and monitoring – by molecular characterization of a patient’s disease, clinicians can select the optimal course of therapy and monitor efficacy over time, as well as quickly react to adjust therapy should treatment resistance arise
- Disease monitoring – to observe disease progression, tumor evolution, residual disease, and early detection of recurrence
- Prognosis of disease
Table of Contents
CHAPTER 1: EXECUTIVE SUMMARY
INTRODUCTION
LIQUID BIOPSY TECHNOLOGIES
INDUSTRY STRUCTURE
LIQUID BIOPSY MARKET REVENUES AND FORECAST
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- Figure 1-1: Global Liquid Biopsy Market by Geographic Region, 2021 (%)
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- Table 1-1: Global Liquid Biopsy Market Forecast, by Region ($ millions), 2021-2026
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- Figure 1-2: Global Liquid Biopsy Market Forecast by Region $ millions), 2021-2026
CHAPTER 2: LIQUID BIOPSY TECHNOLOGIES
INTRODUCTION
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- Table 2-1: Comparison of Tissue and Liquid Biopsy
CURRENT MAJOR LIQUID BIOPSY TECHNOLOGIES
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- Table 2-2: Advantages and Limitations of Major Liquid Biopsy Technologies
CHAPTER 3: CIRCULATING TUMOR DNA (CTDNA) LIQUID BIOPSY
INTRODUCTION
ADVANTAGES AND LIMITATIONS OF CTDNA IN LIQUID BIOPSY
CURRENT CTDNA-BASED LIQUID BIOPSY TESTS
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- Table 3-1: Selected Market-Available ctDNA-based Liquid Biopsy Tests, 2021
- Biocartis
- Biocept
- Biodesix
- CellMax Life
- Circulogene
- Diacarta
- Epigenomics
- Foundation Medicine (Roche)
- Guardant Health
- Inivata (Neogenomics)
- LungLife AI
- Myriad Genetics
- NeoGenomics
- OncoDNA
- Personal Genomic Diagnostics
- QIAGEN
- Resolution Biosciences
- Roche Diagnostics
- Sysmex-Inostics
- Tempus
CTDNA-BASED LIQUID BIOPSY TESTS IN DEVELOPMENT
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- Table 3-2: Selected ctDNA-based Liquid Biopsy Tests in Development
- Exact Sciences
- Freenome
- GRAIL
- Neogenomics
CHAPTER 4: CIRCULATING TUMOR CELLS (CTCS) LIQUID BIOPSY
INTRODUCTION
CHALLENGES IN THE DEVELOPMENT OF CTC-BASED LIQUID BIOPSY TESTS
CTC-BASED LIQUID BIOPSY TESTS
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- Table 4-1: Selected Market-Available CTC-based Liquid Biopsy Tests, 2021
- Adaptive Biotechnologies
- Biocept
- CellMax Life
- Epic Sciences
- GILUPI
- LungLife AI
- Menarini-Silicon Biosystems
- QIAGEN
CTC-BASED LIQUID BIOPSY TESTS IN DEVELOPMENT
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- Table 4-2: Selected CTC-based Liquid Biopsy Tests in Development, 2021
- ANGLE
- Epic Sciences
- Liquid Biotech USA
CHAPTER 5: EXTRACELLULAR VESICLES AND OTHER LIQUID BIOPSY
INTRODUCTION
LIQUID BIOPSY TESTS BASED ON EXTRACELLULAR VESICLES / OTHER ANALYTES
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- Table 5-1: Selected Market-Available Liquid Biopsy Tests based on Extracellular Vesicles / Other Analytes, 2021
- Aspira Women’s Health (formerly Vermillion)
- Biodesix
- Exosome Diagnostics
- Hologic
- MDxHealth
EXTRACELLULAR VESICLE/OTHER ANALYTE-BASED LIQUID BIOPSY TESTS IN DEVELOPMENT
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- Table 5-2: Selected Extracellular Vesicle/Other Analyte-based Liquid Biopsy Tests in Development, 2021
- Circulogene
- OncoCyte
- Resolution Biosciences
- VolitionRx
CHAPTER 6: MULTI-ANALYTE LIQUID BIOPSY TESTS
INTRODUCTION
LIQUID BIOPSY TESTS BASED ON MULTIPLE ANALYTES
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- Table 6-1: Selected Liquid Biopsy Tests That Assess Multiple Analytes, 2021
- Biocept
- Biodesix
- Foundation Medicine (Roche)
- LungLife AI
- NeoGenomics
- OncoDNA
MULTIPLE ANALYTE-BASED LIQUID BIOPSY TESTS IN DEVELOPMENT
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- Table 6-2: Selected Multi Analyte-based Liquid Biopsy Tests in Development, 2021
- Exact Sciences
- Freenome
- GRAIL
- LungLife AI
CHAPTER 7: LIQUID BIOPSY TESTS FOR RESEARCH USE ONLY
INTRODUCTION
LIQUID BIOPSY TESTS FOR RESEARCH USE ONLY
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- Table 7-1: Selected Liquid Biopsy Tests for Research Use Only, 2021
- Agena Bioscience
- ANGLE
- DiaCarta
- Exosome Diagnostics
- Guardant Health
- Natera
- QIAGEN
CHAPTER 8: LIQUID BIOPSY INDUSTRY ANALYSIS
INTRODUCTION
TIERS OF COMPETITION
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- Table 8-1: Selected Participants in the Liquid Biopsy Market, 2021
COMPETITIVE FACTORS
SIGNIFICANT MARKET TRENDS
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- Table 8-2: Significant Trends in the Liquid Biopsy Market, 2021
- Personalized Medicine
- Increasing Global Life Expectancy
- New Liquid Biopsy Products
- Increasing Accessibility of Genetic Testing
- Regulatory Hurdles
- Third-Party Payor Coverage
- Demonstrated Clinical Utility
- Incidence Rates of Specific Cancers
COMPETITORS NO LONGER IN THE LIQUID BIOPSY MARKET
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- Table 8-3: Summary of Companies That Have Exited the Liquid Biopsy Market
CHAPTER 9: LIQUID BIOPSY MARKET
MARKET OVERVIEW
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- Figure 9-1: Global Liquid Biopsy Diagnostics Market Estimate by Analyte, 2021 (%)
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- Figure 9-2: Global Liquid Biopsy Diagnostics Market Estimate by Region, 2021 (%)
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- Figure 9-3: Global Liquid Biopsy Market Estimate by Type of Use, (Research Use, Clinical Diagnostics Use) 2018 (%)
MARKET FORECAST
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- Table 9-1: Global Liquid Biopsy Market Forecast by Region – North America, Europe, Asia Pacific, Rest of World, World ($ millions), 2021-2026
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- Figure 9-4: Global Liquid Biopsy Market Forecast by Region – North America, Europe, Asia Pacific, Rest of World ( $ millions), 2021-2026
CHAPTER 10: MARKET BY ANALYTE
CIRCULATING TUMOR DNA
- Market Overview
- Revenue Forecast
- Table 10-1: Global Liquid Biopsy Market for ctDNA ($ millions), 2021-2026
CIRCULATING TUMOR CELLS
- Market Overview
- Revenue Forecast
- Table 10-2: Global Liquid Biopsy Market for CTCs ($ millions), 2021-2026
EXTRACELLULAR VESICLES AND OTHER ANALYTES
- Market Overview
- Revenue Forecast
- Table 10-3: Global Liquid Biopsy Market for Extracellular Vesicles ($ millions), 2021-2026
MULTIPLE ANALYTES
- Market Overview
- Revenue Forecast
- Table 10-4: Global Liquid Biopsy Market for Multiple Analytes ($ millions), 2018-2023
CHAPTER 11: MARKET BY APPLICATION
THERAPY GUIDANCE AND MONITORING
- Market Overview
- Revenue Forecast
- Table 11-1: Liquid Therapy for Therapy Guidance ($ millions), 2021-2026
DIAGNOSIS/SCREENING
- Market Overview
- Revenue Forecast
- Table 11-2: Global Liquid Biopsy Market for Diagnosis and Screening ($ millions), 2021-2026
DISEASE PROGNOSIS
- Market Overview
- Revenue Forecast
- Table 11-3: Global Liquid Biopsy Market for Disease Prognosis ($ millions), 2021-2026
CHAPTER 12: MARKET BY CANCER TYPE
BREAST CANCER
- Market Overview
- Revenue Forecast
- Table 12-1: Global Liquid Biopsy Market for Breast Cancer ($ millions), 2021-2026
COLORECTAL CANCER
- Market Overview
- Revenue Forecast
- Table 12-2: Global Liquid Biopsy Market for Colorectal Cancer ($ millions), 2021-2026
LUNG CANCER
- Market Overview
- Revenue Forecast
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- Table 12-3: Global Liquid Biopsy Market for Lung Cancer ($ millions), 2021-2026
OVARIAN CANCER
- Market Overview
- Revenue Forecast
- Table 12-4: Global Liquid Biopsy Market for Ovarian Cancer ($ millions), 2021-2026
PROSTATE CANCER
- Market Overview
- Revenue Forecast
- Table 12-5: Global Liquid Biopsy Market for Prostate Cancer ($ millions), 2021-2026
OTHER CANCERS
- Market Overview
- Revenue Forecast
- Table 12-6: Global Liquid Biopsy Market for Other Cancers ($ millions), 2021-2026
Notes: *Including bladder, gastrointestinal, pancreatic, renal, melanoma and hematological malignancies.
PAN-CANCER TESTS
- Market Overview
- Revenue Forecast
- Table 12-7: Global Liquid Biopsy Market for Pan-Cancer Testing ($ millions), 2021-2026
CHAPTER 13: LIQUID BIOPSY COMPANY PROFILES
TOP TEN COMPANIES IN THE LIQUID BIOPSY MARKET
Top Ten Companies in the Liquid Biopsy Market
- ADAPTIVE BIOTECHNOLOGIES
- AGENA BIOSCIENCE, INC.
- ANGLE, PLC
- ASPIRA WOMEN’S HEALTH
- BIOCARTIS GROUP NV
- BIOCEPT, INC.
- BIODESIX
- CELLMAX LIFE
- CIRCULOGENE
- DIACARTA, INC.
- EPIC SCIENCES
- EPIGENOMICS AG
- EXACT SCIENCES
- EXOSOME DIAGNOSTICS, INC.
- FOUNDATION MEDICINE, INC. (ROCHE)
- FREENOME, INC.
- GILUPI GMBH
- GRAIL (ILLUMINA)
- GUARDANT HEALTH, INC.
- HOLOGIC
- LUNGLIFE AI (FORMERLY CYNVENIO BIOSYSTEMS)
- MDXHEALTH
- MENARINI-SILICON BIOSYSTEMS, SPA
- MYRIAD GENETICS, INC.
- NATERA, INC.
- NEOGENOMICS LABORATORIES, INC.
- ONCOCYTE CORPORATION
- ONCODNA S.A.
- ONCIMMUNE
- PERSONAL GENOME DIAGNOSTICS
- PREDICINEQ2 SOLUTIONSQIAGEN N.V.
- Cell-free DNA Technologies
- Exosome and miRNA Technologies
- RESOLUTION BIOSCIENCES (AGILENT)
- ROCHE DIAGNOSTICS
- STAGEZERO LIFE SCIENCES
- SYSMEX-INOSTICS, INC.
- TEMPUS
- VERACYTE
- VOLITIONRX