• Welcome Guest
  • View Cart
  • Phone (US): 703.778.3080
  • 0Shopping Cart
  • Market Reports
  • Market Research Subscriptions
    • Knowledge Center
  • Custom Market Research
    • Quantitative Market Research
    • Qualitative Market Research
    • RateMyProduct
  • Blog
  • Featured
    • Free Downloads
    • View Webinars On-Demand
    • The IVD Market in 2023: $130 Billion and Growing
    • The Point of Care Testing Market
    • Immunoassays
  • About Us
    • Contact
  • Search
  • Menu Menu
  • Biotechnology
    • Next Generation Sequencing
    • Proteomics
    • Biopharmaceuticals
    • Instrumentation & Equipment
    • Emerging Technologies
  • Pharmaceuticals
    • Vaccines
    • Drug Delivery
    • Over-the-Counter
    • Drug Discovery
    • Cancer Treatment
    • Manufacturing & Packaging
    • Prescription Drugs
  • Diagnostics
    • Molecular Assays
    • Point-of-Care
    • Immunoassays
    • Infectious Disease
    • Clinical Chemistry
    • Oncology & Hematology
    • Lab Testing Services
    • Medical Imaging
  • Healthcare
    • Information Technology
    • Facilities & Settings
    • Insurance & Managed Care
  • Medical Devices
    • Wound Care
    • Drug Delivery
    • Equipment
    • Surgical
  • Login
Awaiting product image

Filter your search

Search Report Keyword
Price
CATEGORIES
  • Biotechnology Market Research
  • cell and gene therapy
  • cell therapy
  • Diagnostics Market Research
  • gene therapy
  • Healthcare Information Technology
  • Healthcare Market Research
  • in vitro diagnostic
  • IVD
  • life sciences
  • Medical Devices Market Research
  • Molecular & Nucleic Acid Testing
  • Pharmaceuticals Market Research
  • Point-of-Care Diagnostics
  • sciences
  • vaccines

Knowledge Center Sidebar

Most Popular Research

  • Cell and Gene Therapy Business Outlook
  • The Worldwide Market for In Vitro Diagnostic Tests, 14th Edition
  • Clinical Diagnostics MasterFile
  • The Global Market for Medical Devices, 11th Edition
  • The World Market for Molecular Diagnostics Tests, 10th Edition
  • Remote Patient Monitoring and Telehealth Markets, 12th Edition

Mass Spectrometry in Protein Biomarker Applications – Software, Services, and Instrument Markets

$995.00 – $5,990.00

Clear
SKU: KLI1271710 Categories: Biotechnology Market Research, Instrumentation & Equipment, Proteomics Pages: 184
  • Description
  • Table of Contents
  • Latest reports

Description

Protein biomarkers have become the hot application area for mass spectrometry (MS) and other proteomics-related technologies in the last few years. In the short term, this move towards biomarkers and clinical proteomics research has happened mainly in the drug discovery and development process. However, they also have broad abilities to generate richer information about a disease state, drug response, and/ or the relation between the two; which can be used for diagnostic, prognostic, or various other purposes in the pharmaceutical, diagnostics, and defense industries.

MS has the necessary abilities to rapidly identify biochemicals such as DNA, proteins, or carbohydrates, and thus is currently being used as the workhorse for discovering and validating biomarkers in clinical research, whether for drug development, diagnostic, or other applications. MS technology also far outperforms any alternative for this purpose, due to its particular ability to identify large numbers of components in complex mixtures. These increased abilities have drawn large numbers of life science researchers to procure MS instruments or use available core lab facilities for proteomics experiments.

This report focuses on MS technologies as they are applied to protein biomarker research. It provides in-depth analysis of the markets for:

  • MS Instrumentation,
  • MS Software, and
  • MS Services

In addition to a thorough review of MS products and competitors and the technological and business trends shaping the marketplace, the report provides market data and forecasts for the following as they relate to protein biomarker research:

  • Revenues and growth through 2011 of MS instrumentation
  • Competitive market share by leading supplier
  • Market share by type of MS (Ion Trap, MALDI-TOF, Triple Quad, etc.)
  • Estimated market share by therapeutic area of research
  • Revenues and growth through 2011 for MS services
  • Revenues and growth through 2011 for MS software

The report profiles the top suppliers of MS instrumentation, reviews the regulatory environment, surveys competitive and disruptive technologies, and the details the extensive research collaborations and deals currently underway.

Table of Contents

Chapter One: Executive Summary

  • Proteomics Tools, Approaches in Drug Discovery, Biomarker Discovery
  • Biomarker Validation, Diagnostics, Prognostics
  • Sources of Samples
  • Biomarkers in Pharmaceutical Industry, Diagnostics Industry
  • Drug Discovery and Development
  • Diagnostics
  • Scope and Outline
  • Market Summary

Chapter Two: Introduction

  • Historical Background
  • Definitions
    • Biomarkers
    • Screening Markers
    • Prognostic Markers
    • Staging Markers
    • Stratification Markers
    • Efficacy Markers
    • Target Markers
    • Toxicity Markers
    • Antecedent Markers
    • Translation Markers
    • Surrogate Markers
    • Positive Predictive Value (PPV)
    • Sensitivity
    • Specificity
  • Value of Biomarkers in Industry
  • Mass Spectrometry in Proteomics
    • Software
    • Tandem Mass Spectrometry
    • Types of Mass Spectrometers Used for Protein Biomarkers
    • MALDI-TOF
    • TOF / TOF
    • Triple Quad
    • Quadrupole TOF
    • Quadrupole Ion Trap
    • Fourier Transform MS (FTMS / FT-ICR-MS)
  • Biomarker Discovery
    • MS in Biomarker Applications
    • Biomarker Discovery Process in Diagnostics
    • Biomarker Discovery in Drug Development
  • Biomarker Validation
    • Validation Process in Drug Discovery and Development
    • Validation Process in Diagnostics

Chapter Three: Disease Application Areas

  • Cancer
    • Prostate
    • Prostate Cancer Related Articles:
    • Breast
    • Breast Cancer Related Articles:
    • Lung
    • Ovarian / Endometrial
    • Ovarian Cancer Related Articles:
    • Oral / Lymphoma
    • Oral Cancer Related Articles:
    • Liver
    • Other / Multiple Cancers
    • General Cancer Related Articles:
  • Cardiovascular Disease
  • Neurological Disease
    • Parkinson’s Disease
    • Alcohol Abuse
    • Sleep Apnea
    • Cerebral Injury
    • Amyotrophic Lateral Sclerosis (ALS)
  • Diabetes
  • Aging
    • Aging Related Articles:
  • Sepsis

Chapter Four: Proteomics Tools

  • Introduction
  • 2D Gel Electrophoresis (2DGE)
  • Recent Developments in 2DGE
  • Liquid Chromatography (LC)
  • Recent Developments in LC
  • Protein Chips

Chapter Five: Trends

  • Industry Trends
    • MS Vendors Creating Biomarker Divisions, Collaborations
    • Some Acquisition, Consolidation Trends in Recent Years
    • Regulatory Environment Becoming More Clearly Defined
    • Drug Companies’ Woes Bringing Growth in Biomarkers
    • Intellectual Property Defines Companies’ and Instruments’ Territories
    • Diagnostics Industry Facing Uncertain IP Issues
    • Globalization and Diversity Converging Rapidly
    • Technology Trends
      • Ongoing Debate, Confusion Over Protein Patterns Vs Identified Markers
      • Emphasis on Sample Preparation, Fractionation
      • High Abundance, Low Abundance, Both
      • LC and ESI Approaches Growing Relative To 2DGE and MALDI
      • New Combinations of LC, ESI, and MALDI
      • Integration and Automation
      • Advances in Labels to Address Focused Applications
      • Biomarkers for Classes of Drugs
      • Chemogenomics / Chemoproteomics Techniques Further Driving Advances
      • Direct Analysis of Tissue
      • Shift to Solid-State Lasers
      • Field Applications Driving Miniaturization

Chapter Six: MS Software Market

  • Products and Competitors
    • Agilent Technologies
    • GeneSpring MS
    • MassHunter
    • SpectrumMill
    • Applied Biosystems / MDS Sciex
    • Analyst
    • MarkerView
    • Pro QUANT
    • ProteinPilot
    • Bruker Biosciences
    • ClinProTools
    • flexImaging
    • Cerno Biosciences
    • MassWorks
    • Correlogic Systems
    • Proteome Quest
    • GeneData AG
    • Expressionist Pro
    • GenoLogics Life Sciences Software
    • Proteus
    • Insightful Corp
    • S+Proteome
    • Genstruct
    • Molecular Epistemics platform
    • Matrix Science
    • Mascot
    • Nonlinear Dynamics
    • Progenesis PG600
    • Thermo
    • SIEVE
    • Public Domain Tools and Databases
  • Revenue and Growth Forecast

Chapter Seven: MS Services Market

  • Competitors
    • BG Medicine
    • Biophysical Corporation
    • Caprion Pharmaceuticals
    • Celera Diagnostics
    • Compugen
    • Panatecs
    • Power3 Medical Products
    • Predictive Diagnostics
    • Protein Discovery, Inc
    • RxGen PrimaTox
    • SurroMed
  • Revenue and Growth Forecast

Chapter Eight: MS Instrumentation Market

  • Products
    • Agilent Technologies (Palo Alto, CA)
    • Agilent 1200 Series HPLC-Chip/MS System
    • Agilent 3100 OFFGEL Fractionator
    • Agilent 6210 TOF
    • Agilent 6340 Ion Trap Liquid Chromatograph/Mass Spectrometer (LC/MS)
    • Agilent 6510 Q-TOF LC/MS
    • Multiple Affinity Removal System 7 LC Column and Spin Tube
    • Applied Biosystems / MDS Sciex (Foster City, CA ; Ontario, Canada)
    • 3200 Q TRAP LC/MS/MS System for Proteomics Applications
    • 4000 Q TRAP LC/MS/MS System for Proteomics Applications
    • 4800 MALDI-TOF/TOF
    • ICAT Reagents
    • iTRAQ Reagents
    • QSTAR Elite LC/MS/MS
    • MIDAS TRAQ Systems
    • Becton Dickinson (Franklin Lakes, NJ)
    • P100 Sample Collection Tubes
    • Beckman Coulter (Fullerton, CA)
    • ProteomeLab IgY-12 Partitioning Chemistries
    • Bruker Biosciences (Billerica, MA)
    • apex-Qe
    • autoflex II, autoflex II TOF/TOF
    • ClinProt Large-Protein Beads
    • ClinProt Micro
    • ClinProtRobot
    • Isotope Coded Protein Labels (ICPL) Triplex Kit
    • MALDI Molecular Imager
    • microflex, microflex LT
    • Protein Post-Translational Modification (PTM) Discovery Tool
    • ultraflex, ultraflex TOF/TOF
    • Expression Pathology (Gaithersburg, MD)
    • Liquid Tissue MS Protein Prep Kit
    • PerkinElmer (Wellesley, MA)
    • prOTOF 2000 MALDI O-TOF
    • Qiagen (Venlo, The Netherlands)
    • MSXpress Protein Chip
    • Shimadzu / Kratos (Kyoto, Japan)
    • LCMS-IT-TOF
    • Thermo Electron (Waltham, MA)
    • LTQ XL
    • LTQ FT
    • LTQ Orbitrap
    • MDLC LTQ LC-MS
    • Waters (Milford, MA)
    • LCT Premier XE
    • micro MX
    • Protein Expression System
    • Q-Tof Premier
  • Total Market Size and Growth Forecast
  • The Market by Disease Area
  • Competitive Analysis: Market Share by Vendor
  • Market Share by Product Type

Chapter Nine: Consortia and Alliances

  • The Biomarker Alliance
  • Biomarkers Research Initiatives in Mass Spectrometry (BRIMS)
  • Clinical Proteomic Technologies Initiative for Cancer
  • Clinical Plasma Profiling Consortium
  • Early Detection Research Network (EDRN)
  • HUPO Plasma Proteome Project
  • Oncology Biomarker Qualification Initiative (OBQI)
  • Pharmacogenomics Research Network (PGRN)
  • Predictive Safety Testing Consortium

Chapter Ten: Company Profiles

  • Agilent Technologies (Palo Alto, CA)
  • Applied Biosystems / MDS Sciex (Foster City, CA ; Ontario, Canada)
  • Bruker BioSciences (Billerica, MA)
  • Ciphergen Biosystems (Fremont, CA) (Bio-Rad)
  • GE Healthcare Bio-Sciences (Little Chalfont, United Kingdom) –
  • formerly Amersham Biosciences (Uppsala, Sweden)
  • PerkinElmer (Wellesley, MA)
  • Thermo Electron (Waltham, MA)
  • Waters (Milford, MA)

Chapter Eleven: Deals

Chapter Twelve: Academic / Government / Non-Profit Research

  • The Center for Biomarker Research
  • Johns Hopkins Center for Biomarker Discovery
  • Plasma Proteome Institute

Chapter Thirteen: Competitive or Disruptive Technologies

  • Protein Arrays, Chips
    • Invitrogen ProtoArray
    • Protneteomix Protein, Peptide and Antibody Arrays
    • Whatman Schleicher & Schuell Serum Biomarker Chip
    • Array of Micromachined Ultra Sonic Electrospray (AMUSE)
    • Monogram Biosciences’ (formerly Aclara) eTag Technology
    • Imaging-Based Techniques
    • ELISA

Chapter Fourteen: Challenges

  • Debate Over Serum Proteomics and Biomarkers
  • Advances in Competing, Complementary Techniques, Software Erode Sales
  • Reproducibility is Key Priority But Elusive
  • Clinical Research Not Yet Experienced With Biomarkers, Procedures
  • Blockbuster Mentality Creates Obstacles for Biomarkers
  • Gap Between Pharmaceuticals and Diagnostics Still Wide
  • Large Investment Required for Biomarker Validation Creates Gap
  • Dropping Prices Hurt Revenues, Confuse Customers
  • Regulatory and Ethical Issues Not Completely Resolved
  • Feasibility of Biomarker Approaches Still Unproven
  • Data Analysis Bottleneck Slows Momentum

Chapter Fifteen: Strategic Recommendations

  • Recommendation 1: Software
  • Recommendation 2: Consumables
  • Recommendation 3: Standards, Quality, and Data Exchange
  • Recommendation 4: Reliability and User-Friendliness
  • Recommendation 5: Systems Biology
  • Recommendation 6: Partnering for Novel Technologies
  • Recommendation 7: Drug and Diagnostics Partnerships
  • Recommendation 8: Training and Education

List of Exhibits

Chapter One: Executive Summary

  • Figure 1-1: Market Summary: MS for Protein Biomarker Applications 2005-2011

Chapter Six: MS Software Market

  • Table 6-1: The World Market for Protein Biomarker MS Software (Revenues) 2005-2011
  • Figure 6-1: Trending in the Revenues for Protein Biomarker MS Software 2005-2011
  • Table 6-2: The World Market for Protein Biomarker MS Software (Growth) 2005-2011
  • Figure 6-2: Trending in the Growth of Protein Biomarker MS Software 2005-2011

Chapter Seven: MS Services Market

  • Table 7-1: The World Market for Protein Biomarker Services (Revenues) 2005-2011
  • Figure 7-1: Trending in the Revenues for Protein Biomarker Services 2005-2011
  • Table 7-2: The World Market for Protein Biomarker Services (Growth) 2006-2011
  • Figure 7-2: Trending in the Growth of Protein Biomarker Services 2006-2011

Chapter Eight: MS Instrumentation Market

  • Table 8-1: The World Market for MS Instruments for Protein Biomarker Applications (Revenues) 2005-2011
  • Figure 8-1: Trending in the Revenues for MS Instruments for Protein Biomarker Applications 2005-2011
  • Table 8-2: The World Market for MS Instruments for Protein Biomarker Applications (Growth) 2006-2011
  • Figure 8-2: Trending in the Growth of MS Instruments for Protein Biomarker Applications 2006-2011
  • Table 8-3: Protein Biomarker MS Revenues and Market Share by Disease Area 2005
  • Figure 8-3: Protein Biomarker MS Market Share by Disease Area 2005
  • Table 8-4: Protein Biomarker MS Revenues and Market Share by Leading Supplier 2005
  • Figure 8-4: Protein Biomarker MS Market Share by Leading Supplier 2005
  • Table 8-5: Protein Biomarker MS Revenues and Market Share by Product Type (Ion Trap, MALDI-TOF, Triple Quad, QqTOF, FTMS, Other, Service/Support) 2005
  • Figure 8-5: Protein Biomarker MS Market Share by Product Type 2005

Chapter Nine: Consortia and Alliances

  • Table 9-1: Early Detection Research Network (EDRN) Awardees (Institution, Organ Focus, Technology/Approach, Industry Collaboration)

Chapter Eleven: Deals

  • Table 11-1: Recent Deals, Collaborations, and Alliances

 

    The Worldwide Market for Mass Spectrometry in Clinical Labs, 2024
    September 11, 2024
    Worldwide Sequencer Market, 2023-2028
    August 8, 2024
    The Worldwide Market for Liquid Biopsy, 6th Edition
    December 29, 2023
    The Market for RNA Sequencing, 3rd Edition
    September 8, 2023

Related products

  • Placeholder image

    Worldwide Market for Orthopedic Biomaterials, The

    $2,625.00 – $5,250.00
  • Placeholder image

    Trends in Cell Therapeutics: Promise and Reality

    $3,500.00 – $7,000.00
  • Placeholder image

    Biomarkers – A Market Briefing

    $995.00 – $3,990.00
  • Placeholder image

    Monoclonal Antibodies, Vaccines and Other Immunologic Cancer Treatments – World Market

    $995.00 – $3,990.00

Contact Us

  • 671 North Glebe Road, Suite 1610 Arlington, VA 22203 United States

  • Email Us

  • 703-778-3080

  • Send us a message!

Pay Invoice

  • Pay an Invoice by Credit Card

Follow Us!

Latest Blogs

  • 4 Fascinating Facts About Cancer Diagnostics March 4, 2025
  • Food Animal Diagnostics Market: Spotlight on Disease Testing Amid Bird Flu Surge February 20, 2025
  • Custom Competitive Intelligence (CI) Research: A New Strategic Imperative For Lab Diagnostics Companies  February 19, 2025
  • The Rise of Pharmacodiagnostics in the $10 Billion Global Cancer Diagnostics Market February 1, 2025
  • IVD Trends to Watch: Personalized Medicine Adds Precision to Diagnostic Testing January 2, 2025

Sitemap

  • Home
  • About
  • Blog
  • Contact
  • Sitemap

Your Data and Privacy

  • View our Privacy Policy
  • GDPR Statement
  • Privacy Settings

About Us

Kalorama Information, part of Science and Medicine Group, has been a leading publisher of market research in medical markets, including the biotechnology, diagnostics, medical device, and pharmaceutical industries for more than 30 years. Our comprehensive, timely, quality research and innovative approach to analysis and presentation of market intelligence have made Kalorama Information a premier source of market information for top industry decision makers.

Visit Science and Medicine Group
Medical Imaging Markets, Volume III – UltrasoundClinical Diagnostics in India – Market Sector Analyses and Participant...
Scroll to top