• Welcome Guest
  • View Cart
  • Phone (US): 703.778.3080
  • 0Shopping Cart
  • Market Reports
  • Market Research Subscriptions
    • Knowledge Center
  • Custom Market Research
    • Quantitative Market Research
    • Qualitative Market Research
    • RateMyProduct
  • Blog
  • Featured
    • Free Downloads
    • View Webinars On-Demand
    • The IVD Market in 2023: $130 Billion and Growing
    • The Point of Care Testing Market
    • Immunoassays
  • About Us
    • Contact
  • Search
  • Menu Menu
  • Biotechnology
    • Next Generation Sequencing
    • Proteomics
    • Biopharmaceuticals
    • Instrumentation & Equipment
    • Emerging Technologies
  • Pharmaceuticals
    • Vaccines
    • Drug Delivery
    • Over-the-Counter
    • Drug Discovery
    • Cancer Treatment
    • Manufacturing & Packaging
    • Prescription Drugs
  • Diagnostics
    • Molecular Assays
    • Point-of-Care
    • Immunoassays
    • Infectious Disease
    • Clinical Chemistry
    • Oncology & Hematology
    • Lab Testing Services
    • Medical Imaging
  • Healthcare
    • Information Technology
    • Facilities & Settings
    • Insurance & Managed Care
  • Medical Devices
    • Wound Care
    • Drug Delivery
    • Equipment
    • Surgical
  • Login
Awaiting product image

Filter your search

Search Report Keyword
Price
CATEGORIES
  • Biotechnology Market Research
  • cell and gene therapy
  • cell therapy
  • Diagnostics Market Research
  • gene therapy
  • Healthcare Information Technology
  • Healthcare Market Research
  • in vitro diagnostic
  • IVD
  • life sciences
  • Medical Devices Market Research
  • Molecular & Nucleic Acid Testing
  • Pharmaceuticals Market Research
  • Point-of-Care Diagnostics
  • sciences
  • vaccines

Knowledge Center Sidebar

Most Popular Research

  • Cell and Gene Therapy Business Outlook
  • The Worldwide Market for In Vitro Diagnostic Tests, 14th Edition
  • Clinical Diagnostics MasterFile
  • The Global Market for Medical Devices, 11th Edition
  • The World Market for Molecular Diagnostics Tests, 10th Edition
  • Remote Patient Monitoring and Telehealth Markets, 12th Edition

Outsourcing in Drug Discovery: The Contract Research Organization (CRO) Market, Forecasts to 2018, 6th Edition

$995.00 – $1,990.00

Clear
SKU: KLI5237347 Categories: Drug Discovery Market Reports, Manufacturing & Packaging, Pharmaceuticals Market Research Pages: 200
  • Description
  • Table of Contents
  • Latest reports

Description

For six editions, this authoritative resource has defined the market opportunity for companies assisting in the beginning phase of the drug development process.

This Kalorama Information Report, Outsourcing in Drug Discovery, t provides an in depth look into the trends that have shaped the drug discovery outsourcing market today, and details the current and future global market. As part of its coverage, the report provides markets and forecasts for the following segments.

    • Chemistry Services Market: Building Blocks, Compound

Synthesis, Libraries, Process Research, and Other Services,

    • Biology Market Revenue by Protein Expression, Structural

Analysis, Target Validation, Pathways Analysis, and Other Service

    • Screening Services Market: Assay Development, Primary

Screening, Secondary Screening

  • Lead Optimization Services Market: Early ADMET/Tox, Create Analogues, Computational Support, and Other Services
The drug discovery process consists of iterative cycles between chemistry and biology that begin with the target finding phase, or selecting a protein (a drug target) leading to the identification of a chemical compound with biological activity (a hit). After confirmation of biological activity and chemical feasibility, the hit becomes a lead structure, which is improved through chemical modifications until it fulfills the criteria for a clinical candidate. A drug candidate then moves into the next stage of drug development, the preclinical phase.

The drug discovery process is long, arduous and costly, which has driven outsourcing in this field. The first phase is discovery of a lead compound, a molecule that affects biological function by binding to a target protein or nucleic acid in a way that is useful for treatment of disease. The process by which molecules are identified for their therapeutic value involves synthesis and analysis of many derivatives of the original leads. There are several steps in the drug discovery process including hit confirmation, lead generation, lead optimization, and other studies. Drug discovery is a high-cost, risky business because only a fraction of the therapeutic targets selected for study will actually yield products that achieve regulatory approval by the Food & Drug Administration (FDA).Since the last edition of Kalorama’s Report on the outsourcing of discovery, major trends that have led to an increase in demand for contract services in drug discovery include:The following companies are profiled in the report:

  • Albany Molecular Research, Inc.
  • Aptuit, LLC
  • Argenta Discovery, Ltd.
  • Asclepia MedChem Solutions
  • Asinex Ltd.
  • AsisChem, Inc.
  • Axxam SpA
  • BioDuro
  • BioFocus DPI
  • Caliper Life Sciences
  • Charles River Laboratories, Inc.
  • ChemBridge Corp.
  • Chemical Diversity Inc.
  • Covance, Inc.
  • CreaGen Biosciences, Inc.
  • Crown Bioscience
  • Cyprotex PLC
  • Domainex
  • Emerald Biostructures
  • Enamine Ltd.
  • Evotec AG
  • Exelgen Discovery
  • GVK Biosciences Private Limited
  • GenScript USA Inc.
  • Graffinity Pharmaceuticals GmbH
  • Hutchison MediPharma Ltd.
  • Jubilant Biosys Ltd
  • Nanosyn, Inc.
  • Pharmaron Inc.
  • Ricerca Biosciences, LLC
  • Scynexis, Inc.
  • Selcia Limited
  • Selvita S.A.
  • Shanghai ChemPartner Co., Ltd.
  • Shanghai Medicilon Inc.
  • Sundia Meditech Company, Ltd.
  • Sygnature Discovery Limited
  • TCG Lifesciences Limited
  • Viva Biotech, Ltd
  • WuXI AppTec Co. Ltd.

Table of Contents

ONE: EXECUTIVE SUMMARY

Overview

Scope and Methodology

Introduction

Pharmaceutical Industry Challenges

Number of NMEs and BLAs Approved between 1993-2013

Reducing R&D Spending

The Drug Discovery Process

Accelerating the Drug Discovery Process

Bottlenecks Within the Drug Discovery Process

Outsourcing to Increase Efficiency

Outsourcing Drug Discovery

The Outsourcing Decision

Developing an Outsourcing Plan

Contract Research Organizations

Strategic Versus Tactical Outsourcing Model

Effective Communication Is Essential

Mitigating the Challenges of Protecting IP Rights

Offshoring Contract Drug Discovery

Factors to Consider in Offshore Outsourcing

Benefits of Global Outsourcing

Concerns about Global Outsourcing

Outsourcing to China

Chinese Contract Research Organizations

FDA Offices in China

Outsourcing to India

Drug Discovery Services in India

Outsourcing to Eastern Europe

Drug Discovery Outsourcing Market

Global Economic Downturn Has Minimal Affect on Drug Discovery

Current Market and Forecast

Market Analysis by Segment

TWO: INTRODUCTION TO OUTSOURCING DRUG DISCOVERY

Background

Number of NMEs and BLAs Approved between 1993-2013

Reducing R&D Spending

Ramping up the Pipelines

Outsourcing Drug Discovery

The Outsourcing Decision

Developing an Outsourcing Plan

Decision Criteria

Factors to Consider in Offshore Outsourcing

Benefits of Global Outsourcing

Cost advantage

Access to talent and technologies

Compress Timeline

Concerns about Global Outsourcing

Intellectual Property Protection (IP)

Confidential Information and Trade Secrets

Fraud and Corruption

Meeting Regulatory Compliance Demands

Long Distance

Selecting a Contract Research Organization

Introduction

Choosing the Right CRO

Contract Pharma’s Outsourcing Survey

Global Outsourcing

THREE: THE DRUG DISCOVERY PROCESS

Introduction

Drug Discovery Stages

Accelerating the Drug Discovery Process

Technologies Utilized in Drug Discovery

Bottlenecks Within the Drug Discovery Process

Outsourcing to Increase Efficiency

Outsourcing to Access Novel Technologies

Bioinformatics

Lab-on-a-Chip: Microfluidics in Drug Discovery

FOUR: OUTSOURCING DRUG DISCOVERY

Overview

Is the Traditional Drug Discovery Model Changing?

Outsourcing Drug Discovery Useful Core Management Tool

Contract Research Organizations

Introduction

Role of a CRO

Outsourcing Models

Effective Communication Is Essential for a Successful Partnership

Mitigating the Challenges of Protecting IP Rights

Offshoring Contract Drug Discovery

Introduction

Robust Growth of Outsourcing Drug Discovery in Asia

Outsourcing to China

Introduction

Multi-National Pharmaceutical Companies Establish Research and

Development Facilities in China

Chinese Contract Research Organizations

First Chinese CRO Alliance

FDA Offices in China

China’s Management of Counterfeit Pharmaceuticals, IP Rights and Laws

Outsourcing to India

Introduction

Drug Discovery Services in India

India’s Handling of IP Rights and Laws

FDA Offices in India

Outsourcing to Eastern Europe

Introduction

Russian and Ukraine CROs

FIVE: DRUG DISCOVERY OUTSOURCING MARKET

Overview

Drug Discovery Outsourcing Market

Global Economic Downturn Has Minimal Affect on Drug Discovery

Current Market and Forecast

Market Analysis by Segment

Chemistry Services Market

Market Estimate

Forecast

Biology Services Market

Market Estimate

Forecast

High Throughput Screening Services Market

Market Estimate

Forecast

Lead Optimization Services Market

Market Estimate

Forecast

Contract Drug Discovery Competitors

The Evolving Open-Innovation Model Gaining Traction in Drug Discovery

Alliances between Academic Organizations and CROs

Academic CROs

Alliances between CROs

Market Growth Expanding Global Reach and Scale of Drug Discovery Services

SIX: COMPETITOR PROFILES

Albany Molecular Research, Inc.

History and Lines of Business

Drug Discovery Services

Financial Information

Aptuit, LLC

History and Lines of Business

Drug Discovery Services

Argenta Discovery, Ltd

History and Lines Business

Drug Discovery Services

Asclepia MedChem Solutions

History and Lines of Business

Drug Discovery Services

Asinex Ltd.

History and Lines of Business

Drug Discovery Services

AsisChem, Inc.

History and Lines of Business

Drug Discovery Services

Axxam SpA

History and Lines of Business

Drug Discovery Services

BioDuro

History and Lines of Business

Drug Discovery Services

BioFocus DPI

History and Lines of Business

Drug Discovery Services

Caliper Life Sciences

History and Lines of Business

Drug Discovery Services

Charles River Laboratories, Inc.

History and Lines of Business

Drug Discovery Services

Financial Information

ChemBridge Corp.

History and Background

Drug Discovery Services

Chemical Diversity Inc.

History and Lines of Business

Drug Discovery Services

Covance, Inc.

History and Lines of Business

Drug Discovery Services

Financial Information

CreaGen Biosciences, Inc.

History and Lines of Business

Drug Discovery Services

Crown Bioscience

History and Lines of Business

Drug Discovery Services

Cyprotex PLC

History and Lines of Business

Drug Discovery Services

Domainex

History and Lines of Business

Drug Discovery Services

Emerald Biostructures

History and Lines of Business

Drug Discovery Services

Enamine Ltd.

History and Lines of Business

Drug Discovery Services

Evotec AG

History and Lines of Business

Drug Discovery Services

Financial Information

Exelgen Discovery

History and Lines of Business

Drug Discovery Services

GVK Biosciences Private Limited

History and Lines of Business

Drug Discovery Services

GenScript USA Inc.

History and Lines of Business

Drug Delivery Services

Graffinity Pharmaceuticals GmbH

History and Lines of Business

Drug Discovery Services

Hutchison MediPharma Ltd.

History and Lines of Business

Drug Discovery Services

Jubilant Biosys Ltd

History and Lines of Business

Drug Discovery Services

Nanosyn, Inc.

History and Lines of Business

Drug Delivery Services

Pharmaron Inc.

History and Lines of Business

Drug Discovery Services

Ricerca Biosciences, LLC

History and Lines of Business

Drug Discovery Services

Scynexis, Inc.

History and Lines Business

Drug Discovery Services

Selcia Limited

History and Lines of Business

Drug Delivery Services

Selvita S.A.

History and Lines of Business

Drug Discovery Services

Shanghai ChemPartner Co., Ltd.

History and Lines of Business

Drug Discovery Services

Shanghai Medicilon Inc.

History and Lines of Business

Drug Discovery Services

Sundia Meditech Company, Ltd.

History and Lines of Business

Drug Discovery Services

Sygnature Discovery Limited

History and Lines of Business

Drug Discovery Services

TCG Lifesciences Limited

History and Lines of Business

Drug Discovery Services

Viva Biotech, Ltd

History and Lines of Business

Drug Delivery Services

WuXI AppTec Co. Ltd.

History and Lines of Buisness

Drug Discovery Services

Financial Information

LIST OF EXHIBITS

ONE: EXECUTIVE SUMMARY

Exhibit 1-1: Drug Discovery Timeline: Research to Viable Product to Commercialization

Exhibit 1-2: Number of NME and BLA License Applications Approved between 1993-2013

Exhibit 1-3: PhRMA Members R&D Spending, 1995 through 2012

Exhibit 1-4: The Drug Discovery Process

Exhibit 1-5: Drug Discovery Processes Frequently Outsourced

Exhibit 1-6: Global Drug Discovery Outsourcing Market, 2008-2018

Exhibit 1-7: Market Share of Segments of Drug Discovery Market, 2014

TWO: INTRODUCTION TO OUTSOURCING DRUG DISCOVERY

Exhibit 2-1: Number of NME and BLA License Applications Approved between 1993-2013

Exhibit 2-2: PhRMA Members R&D Spending, 1995 through 2012

Exhibit 2-3: Selection of Global Drug Discovery Outsourcing Collaborations

THREE: THE DRUG DISCOVERY PROCESS

Exhibit 3-1: The Drug Discovery Process

Exhibit 3-2: Drug Discovery Timeline: Research to Viable Product to Commercialization

Exhibit 3-3: Bioinformatics/Pharmacogenomics

Exhibit 3-4: Causes of New Drug Attrition

Exhibit 3-5: Drug Discovery Processes Frequently Outsourced

Exhibit 3-6: Bioinformatics as a Central Hub

FOUR: OUTSOURCING DRUG DISCOVERY

Exhibit 4-1: A Selection of R&D Facilities Closed or Reduced in Size between 2010 and 2014

Exhibit 4-2: A Selection of Chinese Drug Discovery CROs

Exhibit 4-3: A Selection Indian Drug Discovery CROs

Exhibit 4-4: A Selection of Major CROs Operating in Eastern Europe

FIVE: DRUG DISCOVERY OUTSOURCING MARKET

Exhibit 5-1: Global Drug Discovery Outsourcing Market, 2008-2018

Exhibit 5-2:Contract Drug Discovery Services, by Market Segment, 2008-2018

Exhibit 5-3: Market Share Drug Discovery Market Segments, 2014

Exhibit 5-4: Chemistry Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2008-2018

Exhibit 5-5: Chemistry Market Revenue by: Building Blocks, Compound Synthesis, Libraries, Process Research, and Other Services, 2014

Exhibit 5-6: Biology Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2008-2018

Exhibit 5-7: Biology Market Revenue by: Protein Expression, Structural Analysis, Target Validation, Pathways Analysis, and Other Service, 2014

Exhibit 5-8: Screening Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2008-2018

Exhibit 5-9: Screening Services Market: Assay Development, Primary Screening, Secondary Screening, 2014

Exhibit 5-10: Lead Optimization Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery Market, 2008-2018

Exhibit 5-11: Lead Optimization Services Market: Early ADMET/Tox, Create Analogues, Computational Support, and Other Services, 2014

Exhibit 5-12: A Selection of Drug Discovery Contractors, by Market Segment

Exhibit 5-13: A Selection of Collaborations between Academic Organizations and CROs

Exhibit 5-14: Partnerships between Pharma and Academia

Exhibit 5-15: A Selection of Alliances between CROs

Exhibit 5-15: Global Expansion of Contract Drug Discovery Services, East and West

 

    In Vitro Toxicology Market
    July 19, 2018
    100 Companies in Contract Pharmaceutical Research – White Paper
    March 27, 2018
    Outsourcing in Drug Discovery: The Contract Research Organization (CRO) Market, 8th Edition
    March 20, 2018
    Outsourcing in Drug Discovery, 7th Edition
    April 26, 2016

Related products

  • Placeholder image

    Medicare Reform and the Pharmaceutical Industry: Implications of the Medicare Prescription Drug Improvement and Modernization Act of 2003

    $795.00 – $1,590.00
  • Placeholder image

    Outsourcing in Drug Development – The Contract Research Market from Preclinical to Phase III

    $3,500.00 – $7,000.00
  • Placeholder image

    Advanced Drug Delivery: Technologies, Applications, and Markets

    $2,625.00 – $5,250.00
  • Placeholder image

    Cardiovascular Disease: The 45 Market in the United States for Drugs and Medical Devices

    $2,995.00 – $5,990.00

Contact Us

  • 671 North Glebe Road, Suite 1610 Arlington, VA 22203 United States

  • Email Us

  • 703-778-3080

  • Send us a message!

Pay Invoice

  • Pay an Invoice by Credit Card

Follow Us!

Latest Blogs

  • 4 Fascinating Facts About Cancer Diagnostics March 4, 2025
  • Food Animal Diagnostics Market: Spotlight on Disease Testing Amid Bird Flu Surge February 20, 2025
  • Custom Competitive Intelligence (CI) Research: A New Strategic Imperative For Lab Diagnostics Companies  February 19, 2025
  • The Rise of Pharmacodiagnostics in the $10 Billion Global Cancer Diagnostics Market February 1, 2025
  • IVD Trends to Watch: Personalized Medicine Adds Precision to Diagnostic Testing January 2, 2025

Sitemap

  • Home
  • About
  • Blog
  • Contact
  • Sitemap

Your Data and Privacy

  • View our Privacy Policy
  • GDPR Statement
  • Privacy Settings

About Us

Kalorama Information, part of Science and Medicine Group, has been a leading publisher of market research in medical markets, including the biotechnology, diagnostics, medical device, and pharmaceutical industries for more than 30 years. Our comprehensive, timely, quality research and innovative approach to analysis and presentation of market intelligence have made Kalorama Information a premier source of market information for top industry decision makers.

Visit Science and Medicine Group
Mass Spectrometry in Clinical Applications (MALDI-TOF, Triple Quad, QTRAP, Ion...Healthcare Associated Infection (HAI) Control Markets, Forecasts to 2020: Disinfection,...
Scroll to top