Convenience clinics are designed to occupy small spaces and provide just basic care. Therefore, they do not use most of the sophisticated medical equipment found in hospitals or specialty centers such as advanced imaging devices. In fact, while a few larger centers have x-ray machines, most do not. However, retail clinics are becoming relatively large users of point-of-care (POC) tests, clinical chemistry and immunoassay laboratory tests and vaccines. This chapter examines the effect of retail clinics on each of these three supplier market segments.