Description
This Kalorama Information report – The World Anesthesia Drug Market – focuses on three primary segments of anesthesia:
- General Anesthesia
- Local Anesthesia
- Adjunctive Therapies in Anesthesia
The report covers both currently marketed and late stage development anesthesia drugs. For each of these segments the report contains:
- Products on the Market
- Products in Development
- Market Size and Forecast
- Market Share of Key Players
- Issues and Trends
Revenues for each segment were generated using dollar and unit sales for each product. Forecasted figures were generated using a combination of projected surgical procedures, patent and exclusivity expirations, pricing trends, new developments and other factors.
The report includes statistical information for surgical procedures, incidence of conditions requiring surgery, and other relevant information. Statistical information is presented as a worldwide overview, with special emphasis on the U.S. Product chapters in this report provide an overview, description of products on the market, description of products in development, market estimates and forecasts, and competitive analysis of leading providers. The report also includes current issues and trends affecting the industry.
The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information. For the purpose of this study Kalorama Information conducted interviews with more than 50 key industry officials, consultants, health care providers, and government personnel. These sources were the primary basis in gathering information specifically relating to revenue and market share data presented in this report. Specific interviews with pharmaceutical company representatives included marketing directors, division managers, and product representatives.
There are several issues and trends that are impacting the anesthesia drug market. Many of the issues are centered on safety issues, which are probably one of the most important aspects of the administration of anesthetic agents. This industry is a mature industry so it does not have the typical competitive issues often seen in other pharmaceutical segments. However, there are some issues that concern research and development of promising areas in anesthesia.
Topics included in this section include:
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- Introduction
- Regulation of Anesthesia Drugs
- Dentistry and Anesthesia
- Anesthesia and Complications in Pediatric Applications
- Allergic Reactions in Anesthesia ( inc. Propofol Recall)
- Anesthesia and the Benefits to Depression Patients
- Pediatric Studies in Bipolar Disorders
- Anesthesia and Sleep
- Gender Differences in Anesthesia Reaction
- Manufacturing and Supply Issues
- Drug Shortages
- Recreational Use of Anesthetics
- Trends in Conscious Sedation
- Long-term Effects of Anesthesia
- Anesthesia and Numbing Technologies
Several hundred companies compete worldwide in the anesthesia drug market. Companies in the market consist of large pharmaceutical companies, niche pain management and anesthesia drug manufacturers, and worldwide generic drug providers.
All market data pertains to the world market at the manufacturers’ level. The base year for data was 2011. Historical data was provided for the years 2007 through 2010, with forecast data provided for 2012 through 2016. Compound annual growth rates (CAGRs) are provided for the 2007-2011, 2007-2016 and 2012-2016 periods for each industry segment covered. Competitive analysis is provided for the years 2009-2011. The forecasted market analysis for 2012-2016 was highly influenced by the probability of approval and sales of products in late stage development, product marketing, generic competition, and demographic trends.
Table of Contents
ONE: EXECUTIVE SUMMARY
Introduction
Scope and Methodology
Size and Growth of the Market
Issues and Trends Affecting Market
Leading Competitors
TWO: INTRODUCTION
Introduction and History to Anesthesia Drugs
Types of Anesthesia
General Anesthesia
Local Anesthesia
Adjunctive Therapies in Anesthesia
Routes of Administration
Inhalation
Mask Inhalation
Laryngeal Mask
Endotracheal Administration
Controlled Respiration
Intravenous
Topical Application
Transdermal/Transmucosal Application
Distribution Channels
Demographics and Statistics
Medical Procedures by Type
Complications in Anesthesia
Anesthesiology—Work Force
THREE: GENERAL ANESTHESIA
Overview
Stages of General Anesthesia
Induction
Excitement
Surgical Anesthesia
Overdose
Description of Products
Brevital
Diprivan
Ethrane
Forane
Halothane
Ketalar
Lusedra
Pentothal
Suprane
Ultane/Sevorane
Generic Drug Impact and Availability
Research and Development
Market Size and Growth
Total Market
Market by Delivery Method
Market by Geographical Region
Competitive Analysis
FOUR: LOCAL ANESTHESIA
Overview
Techniques of Administration
Topical Application
Transdermal/Transmucosal
Simple Local Infiltration
Regional Injections
Spinal and Epidural Anesthesia
Intrathecal Block
Epidural, Peridural Block
Description of Products
Amides
Carbocaine/Isocaine/Polocaine
Citanest
Exparel
Marcaine/Sensorcaine
Naropin
Septocaine
Xylocaine/LidoSite/Lidoderm
Esters
Cocaine Hydrochloride
Nesacaine
Novocaine
Pontocaine
Combinations
EMLA
Pliaglis
Synera
Generic Drug Impact and Availability
Research and Development
Market Size and Growth
Total Market
Market by Delivery Method
Market by Geographical Region
Competitive Analysis
FIVE: ADJUNCTIVE THERAPIES
Overview
Description of Products
Neuromuscular Blocking Agents
Preanesthetic Sedation and Anesthesia Maintenance
Precedex/dexdor
Anesthesia Reversal Agents
Generic Drug Impact and Availability
Research and Development
Bridion (sugammadex)
Gantacurium
Remimazolam (CNS 7056)
Market Size and Growth
Total Market
Market by Geographical Region
Competitive Analysis
SIX: TOTAL MARKET SIZE AND FORECAST
Total Market Size and Forecast
Anesthesia Market by Product Type
Anesthesia Market by Geographical Region
Competitor Analysis
SEVEN: ISSUES AND TRENDS
Introduction
Regulation of Anesthesia Drugs
Dentistry and Anesthesia
Anesthesia and Complications in Pediatric Applications
Allergic Reactions in Anesthesia
Propofol Recall
Anesthesia and the Benefits to Depression Patients
Pediatric Studies in Bipolar Disorders
Anesthesia and Sleep
Gender Differences in Anesthesia Reaction
Manufacturing and Supply Issues
Drug Shortages
Propofol
Recreational Use of Anesthetics
Trends in Conscious Sedation
Long-term Effects of Anesthesia
Anesthesia and Numbing Technologies
Sedasys
EIGHT: CORPORATE PROFILES
Introduction
Acquisitions, Alliances and Agreements
Hospira and DURECT Corporation
Hospira and Javelin Pharmaceuticals, Inc.
ZARS Pharma and Nuvo Research, Inc.
Abbott Laboratories
AstraZeneca
Baxter International
Eisai Co., Ltd.
Endo Pharmaceuticals, Inc.
Hospira, Inc.
Merck/Schering-Plough
Roche
APPENDIX: List of Companies
LIST OF TABLES
ONE: EXECUTIVE SUMMARY
Table 1-1: The Total World Market for Anesthesia Drugs 2007-2016
Figure 1-1: The Total Market for Anesthesia Drugs 2007-2016
TWO: INTRODUCTION
Table 2-1: World Population by Selected Geographical Region, 2010 – 2050
Figure 2-1: World Population by Selected Geographical Region, 2010–2050
Table 2-2: Procedures by Type, Average Annually 2007-2011
Figure 2-2: Procedures by Type Worldwide, Average Annually 2007-2011
Figure 2-3: Procedures by Type U.S., Average Annually 2007-2011
Table 2-3: Worldwide Anesthesia Complications
Table 2-4: U.S. Physician Work Force (including Anesthesiologists) by Year
Figure 2-4: U.S. Physician Work Force (including Anesthesiologists) by Year
THREE: GENERAL ANESTHESIA
Table 3-1: Marketed Brands for General Anesthesia Drugs
(Brand Name, Generic Name, and Supplier)
Table 3-2: Selected Generic Drug Manufacturers and Products for General Anesthesia
Table 3-3: Brand vs. Generic General Anesthetic Market 2007-2011
Table 3-4: The Market for General Anesthesia Drugs 2007-2016
Figure 3-1: The Market for General Anesthesia Drugs 2007-2016
Figure 3-2: The Market for General Anesthesia Drugs Market Share by Delivery Method, 2011
Table 3-5: The Market for General Anesthesia Drugs Estimated Products Sales by Geographic Region, 2011
Figure 3-3: The Market for General Anesthesia Drugs Market Share by Geographic Region, 2011
Table 3-6: The Market for General Anesthesia Drugs Estimated Revenues and Market Share of Leading Suppliers 2009-2011
Figure 3-4: The Market for General Anesthesia Drugs Estimated Market Share by Leading Suppliers 2011
FOUR: LOCAL ANESTHESIA
Table 4-1: Selected Marketed Local Anesthesia Drugs (Brand Name, Generic Name and Supplier)
Table 4-2: Selected Generic Drug Manufacturers and Products for Local Anesthesia
Figure 4-1: Brand vs. Generic Local Anesthetic Market 2007-2011
Table 4-3: Local Anesthesia Drugs in Development
Table 4-4: The Market for Local Anesthesia Drugs 2007-2016
Figure 4-2: The Total Market for Local Anesthesia Drugs 2007-2016
Figure 4-3: The Market for Local Anesthesia Drugs Market Share by Delivery Method, 2011
Table 4-5: The Market for Local Anesthesia Drugs Estimated Products Sales by Geographic Region, 2011
Figure 4-4: The Market for Local Anesthesia Drugs Market Share by Geographic Region, 2011
Table 4-6: The Market for Local Anesthesia Drugs Estimated Revenues and Market Share of Leading Suppliers 2009-2011
Figure 4-5: The Market for Local Anesthesia Drugs Estimated Market Share by
Leading Suppliers 2011
FIVE: ADJUNCTIVE THERAPIES
Table 5-1: Selected Marketed Adjunctive Therapies in Anesthesia (Type, Brand Name, Generic Name, and Supplier)
Table 5-2: Selected Generic Drug Manufacturers and Products for Adjunctive Therapies in Anesthesia
Figure 5-1: Brand vs. Generic Adjunctive Therapies in Anesthesia Market 2007-2011
Table 5-3: Adjunctive Therapies in Anesthesia in Development
Table 5-4: The Market for Adjunctive Therapies in Anesthesia 2007-2016
Figure 5-2: The Market for Adjunctive Therapies in Anesthesia 2007-2016
Table 5-5: The Market for Adjunctive Therapies in Anesthesia Estimated Products Sales by Geographic Region, 2011
Figure 5-3: The Market for Adjunctive Therapies in Anesthesia Market Share by Geographic Region, 2011
Table 5-6: The Market for Adjunctive Therapies in Anesthesia Estimated Revenues and Market Share of Leading Suppliers 2009-2011
Figure 5-4: The Market for Adjunctive Therapies in Anesthesia Estimated Market Share by Leading Suppliers 2011
SIX: TOTAL MARKET AND FORECAST
Table 6-1: The Total World Market for Anesthesia Drugs 2007-2016
Figure 6-1: The Total Market for Anesthesia Drugs 2007-2016
Table 6-2: Anesthesia Drug Market by Type 2007-2016
Figure 6-2: Anesthesia Drug Market by Type 2007-2016
Figure 6-3: Anesthesia Drug Market by Type 2011
Figure 6-4: Anesthesia Drug Market by Type 2016
Table 6-3: Anesthesia Drug Market Estimated Products Sales by Geographic Region, 2011
Figure 6-5: Anesthesia Drug Market Market Share by Geographic Region, 2011
Table 6-4: Leading Suppliers Anesthesia Revenues and Significant Segments of Participation, 2011
Figure 6-6: Leading Suppliers—Anesthesia Revenues, 2011