Table of Contents
1: Executive Summary
Overview of Gene Editing
Commercial Applications of Gene Editing Technologies
Selected Commercial Gene Editing Products
Industry Structure
Market Trends
Total Market Revenues and Forecast
2: Introduction and Applications of Gene Editing Technologies
Overview of Gene Editing
Current Major Genome Editing Technologies
Commercial Applications of Gene Editing Technologies
Human Therapeutics
Plant Engineering
Animal Breeding/Research Models
3: Gene Editing Technologies
Zinc Finger Nucleases (ZFNs)
Overview
Advantages and Limitations of ZFNs
Selected Commercial ZFN Products
Transcription Activator-Like Effector Nucleases (TALENs)
Overview
Advantages and Limitations of TALENs
Selected TALEN Gene Editing Products and Technologies
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)-Cas9
Overview
Advantages and Limitations of CRISPR-Cas9 Technology
Selected CRISPR-Cas9 Gene Editing Products
Other Gene Editing Technologies
Meganucleases
The rAAV Technology
4: Industry Structure
Tiers of Competition
Barriers to Entry
Competitive Factors
Notable Mergers and Acquisitions
Regulatory Aspects of Genetic Editing
Market Trends
Increasing Development of Therapeutics Using Gene Editing Technologies to
Augment Market Revenues
Intensified R&D Activity in Non-medical Fields to Accelerate Market Growth
Increasing Investments and Funding in Gene Editing Area to Augment Market
Revenues
Growing Awareness about Gene Editing Technologies among Researchers to Spur
Utilization of Gene Editing Technologies
Limitations of Available Technologies to Constrain Market Growth
Ethical Considerations to Restrain Utilization and Market Growth
Regulatory Constraints to Impede Market Expansion
Patent Disputes to Slow Market Growth
5: Total Market Revenues and Forecast
Market Snapshot
Total Market Forecast
Market Revenues and Forecast by Technology
Zinc Finger Nuclease (ZFN) Technologies
TALEN Technologies
CRISPR-based Technologies
Other Gene Editing Technologies
6: Company Profiles
Agilent Technologies, Inc.
Allele Biotechnology
Applied Biological Materials, Inc.
Applied StemCell Inc.
Caribou Biosciences, Inc.
Cellectis, Inc.
CRISPR Therapeutics AG
Dharmacon
DNA2.0, Inc.
Editas Medicine
GeneCopoeia
GenScript
Horizon Discovery Group, Plc
Integrated DNA Technologies
Intellia Therapeutics
MilliporeSigma
ZFN Products
CRISPR/Cas9 Genome Editing Tools
OriGene Technologies, Inc.
PNA Bio, Inc.
Precision BioSciences
Sangamo Biosciences, Inc.
Santa Cruz Biotechnology, Inc.
System BioSciences
Takara Bio USA (Clontech Laboratories)
ThermoFisher Scientific
TALEN Products
CRISPR Products
GeneArt Engineered Cell Models
ToolGen, Inc.
Transposagen, Inc.
CRISPR-Cas9 Products
XTN TALEN Products
TriLink Biotechnology
List of Exhibits
1: Executive Summary
Table 1-1: Advantages and Limitations of Major Commercial Gene Editing
Technologies, 2016
Table 1-2: Selected Commercial Applications of Gene Editing Technologies, 2016 .. 3
Table 1-3: Selected Companies and Commercial Gene Editing Products, 2016
Figure 1-1: Global Revenues and Forecast for the Gene Editing Technologies Market by Geographic Region, 2014-2020 (North America, Europe, Asia Pacific,ROW)
2: Introduction and Applications of Gene Editing Technologies
Table 2-1: Advantages and Limitations of Major Commercial Gene Editing Technologies, 2016
Table 2-2: Selected Gene Editing-Based Therapies in Clinical Development, 2016 . 12
Table 2-3: Selected Agricultural Products Developed Using Gene Editing Technologies, 2016
Table 2-4: Selected Animals Engineered Using Gene Editing Technologies, 2016
Table 2-5: Selected Industrial Products Developed Using Gene Editing Technologies, 2016
3: Gene Editing Technologies
Table 3-1: Advantages and Limitations of ZFN Gene Editing Technologies, 2016
Table 3-2: Selected Commercial ZFN Products, 2016
Table 3-3: Advantages and Limitations of TALEN Gene Editing Technologies, 2016
Table 3-4: Selected Commercial TALEN Gene Editing Products, 2016
Table 3-5: Advantages and Limitations of CRISPR-Cas9 Technology in Gene Editing, 2016
Table 3-6: Selected Commercial CRISPR-Cas9 Gene Editing Tools, 2016
Table 3-7: Advantages and Limitations of Meganucleases and rAAV Technologies in Gene Editing, 2016
4: Industry Structure
Table 4-1: Industry Structure Summary, 2016 (Number and Type of Participating Companies, Key Players, Main Types of Customers, Overall Market Concentration,Key Competitive Factors, Barriers to Entry, Differentiation Strategies, Notable Mergers and Acquisitions)
Table 4-2: Industry Structure – Selected Players in the Market for Gene Editing Technologies, 2016
Table 4-3: Significant Trends in the Market for Gene Editing Technologies, 2016(Near-term Impact [1 year to 2 years]; Long-term Impact [3 years to 5 years])
5: Total Market Revenues and Forecast
Figure 5-1: Estimated Market Breakdown by Type of Product, 2015 (%) (Reagents & tools, Gene editing services, Edited cell lines, Edited animal models)
Figure 5-2: Estimated Market Breakdown by Geographic Region, 2015 (%) (North America, Europe, Asia Pacific, ROW)
Figure 5-3: Estimated Market Breakdown by Application Area, 2015 (%) (Drug discovery & development, Life sciences research, Plants/livestock engineering,Others)
Table 5-1: Global Revenues and Forecast for the Gene Editing Technologies Market by Type of Product, 2014-2020 (Reagents & Tools, Research Services,Genetically-edited Cell Lines, Genetically-edited Animal Models, Total Market)
Figure 5-4: Global Revenues and Forecast for the Gene Editing Technologies Market by Type of Product, 2014-2020 (Reagents & tools, Gene editing services,Edited cell lines, Edited animal models)
Table 5-2: Global Revenues and Forecast for the Gene Editing Technologies Market by Geographic Region, 2014-2020 (North America, Europe, Asia Pacific,ROW)
Figure 5-5: Global Revenues and Forecast for the Gene Editing Technologies
Market by Geographic Region, 2014-2020 (North America, Europe, Asia Pacific, ROW)
Table 5-3: Global Revenues and Forecast for the Gene Editing Technologies
Market by Application Area, 2014-2020 (Drug Discovery & Development, Life Sciences Research, Plants/Livestock Engineering, Other Areas, Total Market)
Figure 5-6: Global Revenues and Forecast for the Gene Editing Technologies
Market by Application Area, 2014-2020 (Drug Discovery & Development, Life Sciences Research, Plants/Livestock Engineering, Others)
Table 5-4: Global Revenues and Forecast for the ZFN Market by Type of Product,2014-2020 (Reagents & tools, Research services, Edited cell lines, Edited animal models, Total Market)
Figure 5-7: Global Revenues and Forecast for the ZFN Market by Type of Product,2014-2020 (Reagents & tools, Gene editing services, Edited cell lines, Edited animal models)
Table 5-5: Global Revenues and Forecast for the TALEN Market by Type of Product, 2014-2020 (Reagents & tools, Research services, Edited cell lines,Edited animal models, Total Market)
Figure 5-8: Global Revenues and Forecast for the TALEN Market by Type of Product, 2014-2020 (Reagents & tools, Gene editing services, Edited cell lines,Edited animal models)
Table 5-6: Global Revenues and Forecast for the CRISPR-based Market by Type of Product, 2014-2020 (Reagents & tools, Research services, Edited cell lines,Edited animal models, Total Market)
Figure 5-9: Global Revenues and Forecast for the CRISPR-based Market by Type of Product, 2014-2020 (Reagents & tools, Gene editing services, Edited celllines, Edited animal models)
Table 5-7: Global Revenues and Forecast for Other Gene Editing Technologies
Market by Type of Product, 2014-2020 (Reagents & tools, Research services,Edited cell lines, Edited animal models, Total Market)
Figure 5-10: Global Revenues and Forecast for Other Gene Editing Technologies
Market by Type of Product, 2014-2020 (Reagents & tools, Gene editing services,Edited cell lines, Edited animal models)
6: Company Profiles
Table 6-1: Selected Companies Active in the Market for Gene Editing Technologies, 2016
