Table of Contents
EXECUTIVE SUMMARY
Overview
The Nosocomial Infection
Market Scope
Research Methodology
Industry Challenges
Total Size and Growth of the Market
Issues and Trends Affecting Market
Leading Competitors
INTRODUCTION AND INDUSTRY TRENDS
Overview
Introduction to Pathogens
Classification of Antibacterial Organisms
Common Hospital (nosocomial) Infections
Description of Infections
Acinetobacter Baumannii
Clostridium Difficile
Gastroenteritis
Hospital-Acquired Pneumonia (HAP)
Pseudomonas Aeruginosa
Staphylococcus Aureus/Methicillin-Resistant Staphylococcus Aureus
Stenotrophomonas Maltophilia
Tuberculosis
Urinary Tract Infections
Vancomycin-Resistant Enterococcus
Ventilator-Associated Pneumonia (VAP)
Patient Risk Factors
General Populations at Risk for Infection
World Demographics
Assessing the Problem: Nosocomial Infection Statistics
Infection Risk Assessments by Hospital Department
Burn Units
Intensive Care Units
Emergency Departments
Hospital Length of Stay
Increased Hospital Length of Stay for HAIs
Extended Stay Environments
International Trends in Nursing Facilities
Economic Trends
Comparison between Healthcare Spending and Real Health Outcomes
U.S. Government’s National Plan to Prevent Healthcare Associated Infections (HAIs)43
Steering Committee
Affordable Care Act (ACA) Funding
Government Funding for HAI Prevention Infrastructure Activities
The Department of Health and Human Services: 2016 Budget Highlights
National Healthcare Safety Network
Hospital infection Surveillance Process
Screening Hospitalized Patients
Pharmaceutical Manufacturer and Marketer Trends
Trends in Partnerships and Alliances
Developers Trends
INFECTION PREVENTION
Overview
Methods of Transmission
Airborne
Contact
Droplet
Vehicle
High-Risk Facilities or Departments
Technology Overview
Potential Use of Copper for Reducing Infections
Wide Area Disinfection Methods
Software for Infection Detection and Control
Antiseptic-Coated Catheters
UV-C Reflective Coatings
Specialized Disinfection/Sterilization Systems
Sterilization vs. Disinfection
Sterilization
Disinfection
Equipment and Solutions
Heat/Steam Sterilization
Product Examples
Chemical Sterilization
Sterilants
Product Examples
Mid-Level Disinfectants
Suppliers
Radiation Sterilization
Product Examples
Sterilization and Disinfection Verification Systems
Market Overview
Hospital infection Prevention Market by Geographical Region
Competitive Analysis
INFECTION TESTING
Overview
Drug-Resistance/Susceptibility Testing
Genotypic Methods
DNA Sequencing
Solid-phase Hybridization Techniques
Microarrays
Real-time Polymerase Chain Reaction Techniques
Phenotypic Methods
Phage-based Assays
Colorimetric Methods
The Nitrate Reductase Assay
Specific Serious Hospital infection Testing
Acinetobacter Baumannii
Clostridium Difficile
Product Examples
Hospital-Acquired Pneumonia
Pseudomonas Aeruginosa
Staphylococcus Aureus
Methicillin-resistant Staphylococcus Aureus (MRSA)
Vancomycin-Intermediate/Resistant Staphylococcus Aureus (VISA/VRSA)
Product Examples
Tuberculosis
Product Examples
Urinary Tract Infections
Vancomycin-resistant Enterococcus
Ventilator-Associated Pneumonia
New Developments
Market Overview
Total Market Size and Forecast
Hospital infection Testing Market by Geographical Region
Competitive Analysis
INFECTION TREATMENT
Overview
Principles of Anti-bacterial Therapy
Infecting Organism
Antibiotic Sensitivity Testing
Site of Infection
Host Defenses and Organ Function
Antibiotic Pharmacokinetics
Monitoring Therapy
Classifications of Antibacterial Products
Carbapenems
Cephalosporins
Macrolides
Penicillins
Quinolones
Sulfonamides
Tetracyclines
Infections and Drug Resistance
Easing Approvals of Antibiotics
Causes of Drug Resistance
Antibiotic Abuse
Antibiotic Use in Agriculture
Drug Resistance in Select Populations
Children
The Elderly
Compromised Individuals
Measures for Reducing Resistance
Testing for the Selection of Anti-bacterial Therapy
Monitoring Therapy
Treatment Guidelines
Clostridium Difficile
Gastroenteritis
Hospital-Acquired Pneumonia
Ventilator-associated Pneumonia
Pseudomonas Aeruginosa
Staphylococcus Aureus
Stenotrophomonas maltophilia
Tuberculosis
Urinary Tract Infections
Leading Products
New Developments
Development Incentives
Total Market Size and Forecast
Hospital infection Treatment Market by Geographical Region
Competitive Analysis
MARKET OPPORTUNITIES FOR HOSPITAL INFECTION CONTROL
Market Considerations
Market Overview
Healthcare-Acquired Infection Distribution by Setting
The Global Market for Hospital infection Control Estimated Market Share by Facility Setting, 2015
The Global Market for Hospital infection Control Estimated Market Share by Hospital Department,2015
Hospital infection Control Market by Geographical Region
Developed and Emerging Market Analysis
COMPANY PROFILES
Introduction
Advanced Sterilization Products
Company Performance
Becton, Dickinson and Company
Company Performance
Belimed
Company Performance
bioMerieux
Company Performance
Cantel
Company Performance
Cepheid
Company Performance
Getinge Group
Company Performance
Merck & Co
Company Performance
Nordion
Company Performance
Pfizer
Company Performance
Roche
Company Performance
Sakura Seiki
Steris
Company Performance
Tso3
Company Performance
LIST OF MAJOR PROVIDERS
LIST OF EXHIBITS
EXECUTIVE SUMMARY
Table 1-1
Frequency of the Most Common Nosocomial Infections
Table 1-2
Growth Drivers and Inhibitors
Table 1-3
The Global Market for Hospital infection Control 2010-2020
Figure 1-1
The Global Market for Hospital infection Control 2010-2020
INTRODUCTION AND INDUSTRY TRENDS
Table 2-1
Global Population at Risk for Serious Bacterial Infections, Secondary to Chronic Diseases by Selected Geographical Region(US, EU, Asia, ROW)
Figure 2-1
Global Population at Risk for Serious Bacterial Infections, Secondary to Chronic Diseases by Selected Geographical Region(US, EU, Asia, ROW)
Table 2-2
Global Population Change, 2005 – 2050
Figure 2-2
Global Population Change, 2005–2050
Table 2-3
World Population by Selected Geographical Region(US, EU, Asia, ROW), 2010 – 205030
Figure 2-3
World Population by Selected Geographical Region(US, EU, Asia, ROW), 2010–205030
Figure 2-4
U.S. Hospital Admissions and Percent of Hospital-acquired Infections (HAIs)by Type – (MRSA, C.diff, Other)
Figure 2-5
European Union Hospital Admissions and Percent of Hospital-acquired Infections(HAIs) by Type (Bloodstream, Upper&Lower RTI, MRSA, Other)
Figure 2-6
Average International Length of Stay (LOS), by Country 2015 Estimates
Figure 2-7
Number of Nursing Homes (United States), 2000-2012
Figure 2-8
Total Healthcare Expenditures as a Percent of GDP by Country 2010 and 2014
Table 2-4
U.S. States ACA HAI Prevention Infrastructure Funding Awards, 2013-2015
Table 2-4 (continued)
U.S. States ACA HAI Prevention Infrastructure Funding Awards, 2013-2015
Table 2-5
U.S. Hospital Acquired Infection Standardized Infection Ratio (SIR)
2010, 2011, 2012 and 2013
Figure 2-9
U.S. Hospital Acquired Infection Standardized Infection Ratio (SIR)
2010, 2011, 2012 and 2013
INFECTION PREVENTION
Table 3-1
Summary of Advantages and Disadvantages of Chemical Agents Used as Chemical Sterilants1 or as High-Level Disinfectants
Table 3-1 (continued)
Summary of Advantages and Disadvantages of Chemical Agents Used as Chemical Sterilants1 or as High-Level Disinfectants
Table 3-2
Comparison of the Characteristics of Selected Chemicals Used as
High-Level Disinfectants or Chemical Sterilants
Table 3-3
Comparison of the Characteristics of Selected Hospital Disinfectants for General Disinfection of Environmental Surfaces
Table 3-4
New Developments, Hospital infection Prevention
Table 3-5
The Global Market for Hospital infection Prevention Equipment and Consumables 2010-2020
Figure 3-1
The Global Market for Hospital infection Prevention Equipment and Consumables 2010-2020
Figure 3-2
The Global Market for Hospital infection Prevention Equipment and Consumables
Estimated Market Value by Use, (Medical Device/Instrument Sterilization,
Wide-Area/Room Sterilization, Medical-grade Disinfection Solutions,
Other Products)2010-2020
Figure 3-3
The Global Market for Hospital infection Prevention Equipment and
Consumables Estimated Market Share by Department/Use, 2015
Figure 3-4
The Global Market for Hospital infection Prevention Equipment and
Consumables Estimated Market Value by Technology, 2010-2020
Figure 3-6
The Global Market for Hospital infection Prevention Equipment and
Consumables Estimated Market Share by Technology, 2015
Table 3-6
The Global Market for Hospital infection Prevention Estimated Products
Sales by Primary Geographic Region 2010-2020
Figure 3-7
The Global Market for Hospital infection Prevention Estimated Product
Sales by Primary Geographic Region 2010-2020
Figure 3-8
The World Market for Hospital infection Prevention Estimated Market
Share by Region, 2015
Table 3-7
The Global Market for Hospital infection Prevention Leading Suppliers’
Shares Estimates for 2015
Figure 3-9
The Global Market for Hospital infection Prevention Leading Suppliers’
Shares Estimates for 2015
INFECTION TESTING
Table 4-1
Significant Approvals for Detecting Serious Hospital infections
Table 4-1 (continued)
Significant Approvals for Detecting Serious Hospital infections
Table 4-1 (continued)
Significant Approvals for Detecting Serious Hospital infections
Table 4-1 (continued)
Significant Approvals for Detecting Serious Hospital infections
Figure 4-1
HAI Test Approvals* in the U.S. by Year and Type, 2000-2015
Table 4-2
New Developments, Hospital infection Testing
Table 4-3
The Global Market for Hospital infection Testing/Diagnostics 2010-2020
Figure 4-2
The Global Market for Hospital infection Testing/Diagnostics 2010-2020
Figure 4-3
The Global Market for Hospital infection Testing/Diagnostics Estimated
Market Share by Test Indication, 2015
Table 4-4
The Global Market for Hospital infection Testing/Diagnostics Estimated
Products Sales by Primary Geographic Region 2010-2020
Figure 4-4
The Global Market for Hospital infection Testing/Diagnostics Estimated
Product Sales by Primary Geographic Region 2010-2020
Figure 4-5
The Global Market for Hospital infection Testing/Diagnostics Estimated
Market Share by Region, 2015
Table 4-5
The Global Market for Hospital infection Testing/Diagnostics Leading
Suppliers’ Shares Estimates for 2015
Figure 4-6
The Global Market for Hospital infection Testing/Diagnostics Leading
Suppliers’ Shares Estimates for 2015
INFECTION TREATMENT
Table 5-1
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-1 (continued)
Treatment Options for Bacterial Infections (Type, Brand, and Manufacturer)
Table 5-2
Antibiotics with Difficult Penetration
Table 5-2 (continued)
Antibiotics with Difficult Penetration
Table 5-3
Annual Sales of Select Antibacterial Products 2014
Table 5-4
New Developments, Hospital infection Treatments, as of December 2015
Table 5-4 (continued)
New Developments, Hospital infection Treatments
Table 5-4 (continued)
New Developments, Hospital infection Treatments
Table 5-5
The Global Market for Hospital infection Treatment 2010-2020
Figure 5-1
The Global Market for Hospital infection Treatment 2010-2020
Table 5-6
The Global Market for Hospital infection Treatment Estimated
Products Sales by Primary Geographic Region 2010-2020
Figure 5-2
The Global Market for Hospital infection Treatment Estimated
Product Sales by Primary Geographic Region 2010-2020
Figure 5-3
The Global Market for Hospital infection Treatment Estimated
Market Share by Region, 2015
Table 5-7
The Global Market for Hospital infection Treatment Leading
Suppliers’ Shares Estimated Share for HAIs for 2015
Figure 5-4
The Global Market for Hospital infection Treatment Leading
Suppliers’ Shares Estimated Share for HAIs for 2015
MARKET OPPORTUNITIES FOR HOSPITAL INFECTION CONTROL
Table 6-1
The Global Market for Hospital infection Control 2010-2020
Figure 6-1
The Global Market for Hospital infection Control 2010-2020
Figure 6-2
The Global Market for Hospital infection Control Estimated
Market Share by Segment, 2015
Figure 6-3
The Global Market for Hospital infection Control Estimated Market
Share by Facility Setting, 2015
Figure 6-4
The Global Market for Hospital infection Control Estimated Market
Share by Hospital Department, 2015
Table 6-2
The Global Market for Hospital infection Control Estimated Products
Sales by Primary Geographic Region 2010-2020
Figure 6-5
The Global Market for Hospital infection Control Estimated Product
Sales by Geographic Region 2010-2020
Figure 6-6
The Global Market for Hospital infection Control Estimated Market
Share by Geographic Region, 2015
Table 6-3
Developed vs. Emerging Markets
Figure 6-7
The Global Market for Hospital infection Control
Estimated Market Share by Region, 2015
COMPANY PROFILES
LIST OF MAJOR PROVIDERS
