Description
The Global Market for Biomarkers (Cancer Biomarkers, Cardiovascular Disease Biomarkers, Immunological Disease Biomarkers, Infectious Disease Biomarkers, Neurological Disease Biomarkers, Novel Biomarkers for Other Diseases)
The Global Market for Biomarkers analyzes the current and future markets for biomarkers. The report provides a market analysis for six broad areas of medical biomarkers:
- The Market for Cancer Biomarkers
- The Market for Cardiovascular Disease Biomarkers
- The Market for Immunological Disease Biomarkers
- The Market for Infectious Disease Biomarkers
- The Market for Neurological Disease Biomarkers
- The Market for Novel Biomarkers for Other Diseases
For each area, selected biomarkers and companies developing/marketing these biomarkers are provided.
Market analyses in this report cover world markets for biomarker diagnostic markets, including the following segmentation:
- Worldwide Diagnostic Biomarker Market by Disease Indication – 2015 and 2020
- Worldwide Cancer Biomarkers Diagnostic Market – 2015 and 2020
- Worldwide Cardiovascular Disease Biomarkers Diagnostic Market – 2015 and 2020
- Worldwide Autoimmune Disease and Allergy Biomarkers Diagnostic Market – 2015 and 2020
- Worldwide Infectious Disease Biomarkers Diagnostic Market – 2015 and 2020
- Worldwide Diagnostic Market for Selected Other Biomarkers – 2015 and 2020
- Worldwide Biomarker Market – Diagnostic versus Research Applications – 2015 and 2020
- Worldwide Biomarker Market by Geography – 2015 and 2020 (North America, European Union, Japan, ROW, Total)
The world markets for biomarkers and biomarker tests are provided in U.S. dollars for 2015 and 2020. The worldwide market for biomarkers by disease indication is provided, including the market for tests for biomarkers (diagnostics products) sold to clinical laboratories, and also products sold to researchers.
Biomarkers can be used for a range of diagnostic applications including predicting disease risk, diagnosis, predicting prognosis, identifying appropriate therapy for an individual, monitoring disease or for return of a disease, and other applications. Biomarkers also have important roles in drug discovery and development.
The biomarker market is large, reflecting the large market for diagnostic tests based on these biomarkers, and also the ongoing efforts to discovery, validate, and commercialize new biomarkers. Growth in this market is fueled by factors that are fostering the growth of both the research and the diagnostics market. Market drivers and challenges are discussed in the report.
The large and growing biomarker market has attracted a lot of attention, and companies entering the market. Thus this has become a highly competitive market. The report profiles companies involved in the biomarkers market.
The information presented in this report is derived from publicly available information sources such as company reports and announcements, government reports and databases, medical organization reports, medical associations, and other publications. The analysis is based on the author’s industry knowledge combined with literature searches and discussions with industry professionals and experts in the areas of point-of-care tests, decentralized healthcare and healthcare economics.
Table of Contents
ONE: EXECUTIVE SUMMARY
Overview
Scope and Methodology
Market Overview
Prognosis for Growth
TWO: INTRODUCTION
What Are Biomarkers?
Point-of-View
THREE: SELECTED TECHNOLOGIES USED TO IDENTIFY AND ANALYZE BIOMARKERS
Immunoassays
Overview – Immunoassays
Immunoassay Instrument Platforms
Immunohistochemistry (IHC)
Flow Cytometry
In Situ Hybridization
Nucleic Acid Amplification Technologies
Analysis of Gene Expression Patterns (Gene Signatures)
Microarrays
Protein Microarrays
DNA Microarrays
Chromosomal Microarrays
Tissue Microarrays
Sequencing Technologies
Sanger Sequencing
Early Next Generation Sequencing Technologies
Sequencing by Synthesis (SBS)
Supported Oligonucleotide Ligation and Detection (SOLiD)
Ion Torrent Sequencing
Newer Next Generation Sequencing Technologies
Sequencing Technologies Summary – Impact on Biomarkers
Mass Spectrometry
Mass Spectrometry Technology
Research and Clinical Applications of Mass Spectrometry
Non-Invasive Prenatal Testing
Liquid Biopsies – Circulating Tumor Cells and Circulating Tumor DNA(Cell Free DNA)
Digital Pathology and Image Cytometry
Information Technology
FOUR: CANCER BIOMARKERS
Overview
Cancer Biomarkers
Assessing Risk of Cancer
Cancer Screening
Diagnosis and Monitoring of Cancer
Predicting Prognosis
Personalized Medicine/Precision Testing
Competition in Cancer Biomarkers
FIVE: CARDIOVASCULAR DISEASE BIOMARKERS
Overview
Acute Myocardial Infarction and Acute Coronary Syndrome
Heart Failure
Lipid Disorders
SIX: IMMUNOLOGICAL DISEASE BIOMARKERS
Autoimmune Disease Biomarkers
Inflammation/Inflammatory Disease Biomarkers
Selected Other Immune-Related Disorders
SEVEN: INFECTIOUS DISEASE BIOMARKERS
Overview
Current Infectious Disease Diagnostics and Emerging Threats
Antibiotic Resistance
Sepsis
EIGHT: NEUROLOGICAL DISEASE BIOMARKERS
Overview
Alzheimer’s Disease
Emerging Biomarkers for Neurological Disorders
NINE: NOVEL BIOMARKERS FOR OTHER DISEASES
Overview
Companies Developing Novel Biomarkers
TEN: DEALS
ELEVEN: BIOMARKERS – MARKET DRIVERS AND CHALLENGE
Biomarker Markets
Market Drivers for Diagnostic Applications of Biomarkers
Issues and Hurdles Faced by In Vitro Diagnostic Companies
Market Drivers for Research Applications of Biomarkers
Biomarkers in Drug Development
Pharmacogenomic Biomarkers
Advances in Technology Changing the Future of Biomarkers
Biomarker Panels
Working Together to Discover and Validate New Biomarkers – Alliances,
Consortiums, and Other Groups
Validation of Biomarkers
Future Prospects
TWELVE: BIOMARKER MARKET ANALYSIS
Diagnostic Biomarker Market by Disease Indication
Cancer Biomarkers
Cardiovascular Disease Biomarkers
Autoimmune Disease and Allergy Biomarkers
Infectious Disease Biomarkers
Biomarkers for Other Diseases
Biomarker Market – Research versus Diagnostic Applications
Biomarker Market – Geographical Distribution
THIRTEEN: COMPANY PROFILES: BIOMARKER COMPANIES
14M Genomics Ltd.
20/20 GeneSystems, Inc
23andMe, Inc.
A&G Pharmaceutical, Inc.
Abacus Diagnostica Oy
Abbott Laboratories
Recent Revenue History
Company Overview – Focusing on Biomarkers
Abcodia Ltd.
Accelerate Diagnostics, Inc.
Recent Revenue History
Company Overview
Acobiom
ACT Genomics Co., Ltd.
Acumen Pharmaceuticals, Inc.
Adaptive Biotechnologies Corporation
Adlyfe Inc.
Admera Health (A GENEWIZ Company)
AESKU.DIAGNOSTICS
Affymetrix, Inc.
Recent Revenue History
Company Overview
Agena Bioscience Inc.
Agendia NV
Agilent Technologies Inc.
Recent Revenue History
Company Overview
Alere Inc.
Recent Revenue History
Company Overview
Almac Group Limited
ALPCO
Amarantus BioScience Holdings, Inc.
Ambry Genetics Corp.
Aperiomics, Inc.
ApoCell, Inc.
Applied Proteomics, Inc.
Associates of Cape Cod, Inc. (ACC)
Asuragen, Inc.
AsymmetRx Medical, Inc.
Athena Diagnostics, Inc. (A Quest Diagnostics Business)
Atlas Genetics Ltd
Atossa Genetics Inc.
Recent Revenue History
Company Overview
Augurex Life Sciences Corp.
Augurix SA/Augurix Diagnostics
Avant Diagnostics, Inc. (Formerly Arrayit Diagnostics Inc.)
Axela, Inc
Axis-Shield Diagnostics, Ltd. (An Alere Company)
Recent Revenue History
Company Overview
AXO Science
Banyan Biomarkers, Inc.
Beckman Coulter, Inc.
Recent Revenue History
Company Overview
Becton, Dickinson and Company (BD)
Recent Revenue History
Company Overview
BG Medicine, Inc.
Recent Revenue History
Company Overview
The Binding Site Group Ltd.
Recent Revenue History
Company Overview
Biocartis SA
Recent Revenue History
Company Overview
Biocrates Life Sciences AG
Biodesix, Inc.
BioFire Diagnostics, LLC (Acquired by bioMérieux)
Recent Revenue History and Other Financial Information
Company Overview
Biohit Oyj
Recent Revenue History
Company Overview
Bioinnovation Solutions SA
BioMarker Strategies
BioMedomics, Inc.
bioMérieux SA
Recent Revenue History
Company Overview
BioMosaics Inc.
BioPorto Diagnostics A/S
Recent Revenue History
Company Overview
Bio-Rad Laboratories, Inc.
Recent Revenue History
Company Overview
BioSystems International
bioTheranostics, Inc. (A bioMérieux Company)
Biotype Diagnostic GmbH
BIOUNIVERSA s.r.l.
Cancer Genetics, Inc.
Recent Revenue History
Company Overview
Caprion, Inc.
CardioDx, Inc.
CardioGenics Holdings Inc.
CareDx, Inc.
Recent Revenue History
Company Overview
Caris Life Sciences
Castle Biosciences, Inc.
CD Diagnostics, Inc.
Cellmid Ltd.
Centogene AG
Cepheid
Recent Revenue History
Company Overview
Chronix Biomedical, Inc.
Clarient Diagnostic Services, Inc. (A GE Healthcare Company; Being Acquired by
NeoGenomics, Inc.)
Recent Revenue History
Company Overview
Courtagen Life Sciences, Inc.
Crescendo Bioscience (Subsidiary of Myriad Genetics)
Critical Diagnostics
Curetis AG
Cynvenio Biosystems, Inc.
Dako A/S (An Agilent Company)
Recent Revenue History
Company Overview
Danaher Corporation
Recent Revenue History
Company Overview
deCODE genetics
Diadexus, Inc
Recent Revenue History
Company Overview
DiaGenic ASA
Diagenics SE
Diagenics International Corporation
Diaxonhit
Recent Revenue History
Company Overview
DNA Electronics Ltd. (DNAe)
EntroGen, Inc.
Epic Sciences, Inc.
Epigenomics AG
Recent Revenue History
Company Overview
Epinex Diagnostics, Inc.
Eutropics Pharmaceuticals
Exact Sciences Corporation
Recent Revenue History
Company Overview
Exiqon A/S
Recent Revenue History
Company Overview
Foundation Medicine, Inc.
Recent Revenue History
Company Overview
Fujirebio Inc.
Fujirebio Diagnositics, Inc.
Recent Revenue History
Company Overview
Gamma Therapeutics, Inc.
Genalyte, Inc.
GeneCentric Diagnostics, Inc.
Genection, Inc. (An Invivoscribe Company)
GeneNews Limited and Innovative Diagnostic Laboratory
GenomeDx Biosciences
Genomeon LLC
Genomic Health, Inc.
Recent Revenue History
Company Overview
Genomic Vision
Recent Revenue History
Company Overview
Genoptix (A Novartis Company)
Guardant Health, Inc.
HalioDx
Helomics Corporation
Hologic, Inc.
Recent Revenue History
Company Overview
Illumina, Inc.
Recent Revenue History
Company Overview
Immunexpress
Integrated Diagnostics, Inc.
Intrinsic LifeSciences
Myriad Genetics, Inc.
Recent Revenue History
Company Overview
NanoString Technologies, Inc.
Recent Revenue History
Company Overview
NeoGenomics, Inc./NeoGenomics Laboratories
Recent Revenue History
Company Overview
Oncolab, Inc.
Oncospire Genomics
OPKO Health, Inc./OPKO Diagnostics
Recent Revenue History
Company Overview
ORGENTEC Diagnostika GmbH
Orion Genomics
Ortho-Clinical Diagnostics
Recent Revenue History
Company Overview
Oxford Gene Technology
Proteome Sciences plc
Recent Revenue History
Company Overview
Psynova Neurotech Ltd.
QIAGEN N.V.
Recent Revenue History
Company Overview
Quanterix Corporation
Randox Laboratories Ltd
Rapid Pathogen Screening, Inc.
ReLIA Diagnostics, Inc.
RENESE UG
Roche
Recent Revenue History
Company Overview
Siemens Healthcare Diagnostics
Recent Revenue History
Company Overview
Sysmex Corporation
Recent Revenue History
Company Overview
Thermo Fisher Scientific, Inc.
Recent Revenue History
Company Overview
Tosoh Corporation
Recent Revenue History
Company Overview
Ventana Medical Systems, Inc. (Member of the Roche Group)
Wako Pure Chemical Industries, Ltd.,
XRGenomics LTD
ZEUS Scientific, Inc.
