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The Market and Potential for CRISPR/Cas9 Gene Editing

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SKU: KLI15596715 Category: Biotechnology Market Research Pages: 101
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Description

The Market and Potential for CRISPR/Cas9 Gene Editing 

 This report consolidates the information and trends and provides reliable market estimates for CRISPR technology to 2023. As part of the report’s coverage, it provides the following:
 
  • Market Size and Forecast for CRISPR/Cas9 Gene Editing, 2017-2023 
  • The Market for CRISPR/Cas9 by Region (N. Amer. EU, ROW), 2017-2023 Analysis of Growth Trend by Region
  • Market by Application (Cancer Research, Non-Cancer Disease Research, Cancer Diagnostics, Infection Diagnostics, Plant, Food, Biofuel, Drug Discovery, Drug Development, Other) 
  • Growth Trend, U.S.
  • Growth Trend, Outside U.S. 
  • Market by End User (Hospitals, University, Medical Research Institute, Government), 2017 
  • Market by End User (Hospitals, University, Medical Research Institute, Government), 2023 
  • Recent Technology and Market Developments and Medical Studies
  • Partnerships Involving CRISPR Gene Editing
Companies in the Market and Partnerships in Gene Editing
In 2018, more than 30 players participate in this market, from large multinational corporations to small, niche life sciences companies.  Key players include Agilent, MilliporeSigma, GE Healthcare Dharmcon, GeneScript, Horizon Discovery Group, OriGene, ThermoFisher Scientific, Transposagen, and ToolGen. These companies develop and commercialize various products and services for each of the major gene editing technologies.
The nature of CRISPR’s complex technology requires partnerships between the developers of the technology and the healthcare concerns with distribution strength and a broader product base. These developments are outlined in the report.
Recent Lawsuit and Industry Risk Analysis 
Currently, one of the more significant factors in commercializing CRISPR-Cas9 as a viable therapeutic tool is the current legal battles surrounding the technology. The issue started when both the University of California, Berkeley (UCB) and the Broad Institute of MIT (the Broad) both filed patents related to this technology. While there’s been some resolution, the report provides an analysis of developments.

Table of Contents

1: EXECUTIVE SUMMARY

OVERVIEW

gRNA

 

Enzyme

Figure 1-1: PubMed References for “CRISPR” 2011-est. 2018

INDUSTRY RISK ANALYSIS – PATENT LANDSCAPE

Impact of the Initial Ruling

How Things Stand Now in the US

How Things Stand in Europe

Conclusions

OTHER RECENT CRISPR/CAS9 DEVELOPMENTS

NIH GRANTS FOR CRISPR PROJECTS

Figure 1-2: Grants for CRISPR-based Projects, NIH

CRISPR/Cas9 NIH Projects by End User

Figure 1-3: NIH Project Grant Recipients by type

THE MARKET FOR CRISPR EQUIPMENT AND SUPPLIES

Figure 1-4: Market for CRISPR Technologies, 2017-2023

Market by Geography

Table 1-1: CRISPR Gene Editing Market, 2017-2023

TRENDS IN GENE EDITING

Table 1-2: Significant Trends in the Market for Gene Editing Technologies, 2016

SIGNIFICANT PARTNERSHIPS IN GENE EDITING

Table 1-3: Selected Gene Editing Partnerships

2: CRISPR PRODUCTS AND TRENDS

 

OVERVIEW

Advantages and Disadvantages of CRISPR

Table 2-1 Advantages and Limitations of CRISPR-Cas9 Technology in Gene Editing, 2016

RECENT APPLICATIONS AND DEVELOPMENTS

Malaria Control

 

Gene-Edited Sheep for Regenerative Medicine

 

Improved Vaccine Creation

 

Obesity Control

 

Epstein-Barr Virus

 

Protein Coding

 

Improving Chinese Herbs

 

Identifying Drug Resistance Mutations

 

Immune Therapies for Cancer

 

Enabling Bacterial Cell Factories

 

Muscular Dystrophy

 

“Piggy Bac” Process for Stem Cells

 

Clarity on Salmonella Ser. Kentucky

 

Better Human Disease Models

 

Editing of Bread Wheat

 

Cancer Cell Phagocytosis

 

Refining Gene Editing

 

COMPANIES IN CRISPR GENE EDITING

Table 2-2: Products on the Market

COMMERCIAL APPLICATIONS OF GENE EDITING TECHNOLOGIES

 

USING CRISPR FOR DIAGNOSTICS

 

USING CRISPR FOR HUMAN THERAPEUTICS

 

Table 2-3: Gene Editing-Based Therapies

 

Selected CRISPR-Cas9 Gene Editing Products

 

Table 2-4: Commercial Gene Editing Products on the Market

 

CRISPR COMPANIES

 

Agilent

 

Allele Biotechnology

 

Applied Biological Materials

 

Dharmacon

 

DNA 2.0

 

GeneCopoeia

 

GenScript

 

Horizon Discovery Group, Plc

 

Integrated DNA Technologies

 

MilliporeSigma

 

OriGene

 

PNA Bio

 

Santa Cruz Biotechnology

 

System BioSciences

 

Takara Bio (Clontech)

 

ThermoFisher Scientific

 

ToolGen

 

TriLink Biotechnology

 

Table 2-5 Significant Trends in the Market for Gene Editing Technologies, 2018

 

3: GENE EDITING MARKET ANALYSIS

 

COMPETITIVE ANALYSIS

THE MARKET FOR CRISPR EQUIPMENT AND SUPPLIES

Figure 3-1: Market for CRISPR Technologies, 2017-2023

Market by Geography

Table 3-1: CRISPR Gene Editing Market (N. Amer. EU, ROW), 2017-2023

GROWTH TREND

Figure 3-2: Growth Trend in the CRISPR Market, 2017-2022

Growth Trend in North America and Europe

Figure 3-3: Growth Trend in North America and Europe

Growth Trend in the Rest of the World

Figure 3-4: Growth Trend in the Rest of the World

MARKET BY APPLICATION

Figure 3-5: Market by Application (Cancer Research, Non-Cancer Disease Research, Cancer Diagnostics, Infection Diagnostics, Plant, Food, Biofuel, Drug Discovery, Drug Development, Other)

MARKET BY END USER

Figure 3-6 Market by End User (Hospitals, University, Medical Research Institute, Government), 2017

Figure 3-7 Market by End User (Hospitals, University, Medical Research Institute, Government), 2023

4: GENE EDITING PARTNERSHIPS

 

CARIBOU BIOSCIENCES, INC.

 

SANGAMO BIOSCIENCES

Shire International

 

Pfizer Inc.

 

Bioverativ Inc.

 

CRISPR THERAPEUTICS

 

Bayer

 

Vertex Pharmaceuticals

 

MaSTherCell

 

Neon Therapeutics

 

Massachusetts General Hospital Cancer Center

 

CureVac AG

 

EDITAS MEDICINE

 

Allergan plc

 

Adverum

 

Juno Therapeutics

 

INTELLIA THERAPEUTICS

 

Regeneron Pharmaceuticals

 

Novartis

 

PRECISION BIOSCIENCES

 

BLUEBIRD BIOTECHNOLOGIES

 

CHRISTIANA CARE’S GENE EDITING INSTITUTE

 

The Wistar Institute

 

NovellusDx

 

Analytical Biological Services

 

CASEBIA THERAPEUTICS

 

CRISPR Therapeutics and MaxCyte

 

Seattle Children’s Research

 

CRISPR Therapeutics and CureVac AG

 

SYNTHEGO

 

Thermo Fisher Scientific

 

SAREPTA THERAPEUTICS

 

HOMOLOGY MEDICINES

 

GENSCRIPT

 

CELLECTIS, INC.

 

Pfizer

 

Servier

 

MERCK

 

TWIST BIOSCIENCE, DESKTOP GENETICS

 

ASTRAZENECA

 

The Wellcome Trust Sanger Institute

 

The Innovative Genomics Initiative

 

Thermo Fisher Scientific

 

Broad Institute / Whitehead Institute

 

Table 4-1: Selected Gene Editing Partnerships

 

INCREASING INVESTMENTS AND FUNDING IN GENE EDITING AREA TO AUGMENT MARKET REVENUES

Exonics Therapeutics

 

Synthego

 

Homology Medicines

 

Editas Medicine

 

Intellia Therapeutics

 

CRISPR Therapeutics

Poseida Therapeutics

 

Recombinetics

Table 4-2: Selected Gene Editing Investments

 

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