The Market for Molecular Histology and Cytology (HPV, in situ hybridization, CTCs, Others)
In Situ Hybridization, HPV Testing, Circulating Tumor Cells and Flow Cytometry are important histology and cytology approaches to testing. In situ hybridization and more specifically fluorescent in situ hybridization (FISH) techniques use DNA probes to detect pathogens and molecular structures in cells. More recently flow cytometry techniques and other cell capture devices allow lab professionals to select targeted cells that can be further analyzed with PCR, sequencing and mass spectrometry.
The result so far has been gene patterns that help distinguish cell and tumor attributes that demonstrate the presence of disease as well as risk for disease progression and sensitivity to specific therapeutics. A growing population of cancer patients has increased the number of histology analyses performed.
This Kalorama report contains market sizes and forecasts for these technologies, identifies drivers and market trends, and identifies the competitive situation in the market. Kalorama’s analysis is the result of detailed research into secondary literature and primary interviews to develop reliable business planning information for entrants or investors in this market. Over 25 Company profiles are included as part of the research in this report.
Table of Contents
CHAPTER ONE: EXECUTIVE SUMMARY
Size and Growth in the Market
CHAPTER TWO: MARKET ANALYSIS
Market by Geographic Region
In Situ Hybridization
Fluorescence in situ Hybridization (FISH)
Molecular HPV and Pap Smear
Circulating Tumor Cells
CHAPTER THREE: COMPANY PROFILES
Advanced Cell Diagnostics (ACD)
Amoy Diagnostics Co. Ltd.
Applied Spectral Imaging Inc. (ASI)
Beckman Coulter, Inc. / Danaher
Becton, Dickinson and Company (BD) Franklin Lakes, NJ www.bd.com
Cymogen Dx, LLC
DxTerity Diagnostics Inc.
General Electric – GE Healthcare
HTG Molecular Diagnostics
Kapa Biosystems Inc.
PreTect AS (formerly Norchip)
Sony Biotechnology ( iCyt )
Sysmex Corporation Kobe, Japan
Ventana Medical Systems Inc.
TABLE OF EXHIBITS
Figure 1-1: Market Trend by Type, 2015 and 2020 (in situ hybridization, HPV, Tissue
Microarrays, CTC, Flow Cytometry)
Table 2-1: Worldwide Molecular Histology/Cytology Sales, by Type, 2015 and 2020 (in situ
hybridization, HPV, Tissue Microarrays, CTC, Flow Cytometry)
Figure 2-1: Molecular Histology and Cytology Sales, 2015 and 2020
Figure 2-2: Worldwide Molecular Histology/Cytology Sales, by Region
(US, EU, Asia, ROW)
Table 2-2: Selected Molecular Histology Innovations, 2015
Table 2-3: Selected FFPE DNA/RNA Sample Preparation Innovations
Table 2-4: Selected Companies with in situ hybridization tests on the Market or
In Development for Cancer Diagnostics (Company, Comment, Market Status)
Figure 2-3: Pap and Molecular HPV Market Trend Compared
Table 2-5: Selected HPV Test Innovations
Table 2-6: Selected Innovations in CTC Technology
Table 2-7: Selected Companies Marketing Flow Cytometry Platforms or Consumables
Table 2-8: Major Pharmacodiagnostic Markers
Table 2-9: Selected Pharmacodiagnostic Histology Tests 33