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The World Market for Pain Management Drugs and Devices

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SKU: KLI5042319 Categories: Drug Discovery Market Reports, Pharmaceuticals Market Research Pages: 270
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  • Table of Contents
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Description

The World Market for Pain Management Drugs and Devices encompasses a wide variety of products that treat and ease pain. The field of pain management is currently experiencing a busy and interesting period; and as a result, the range of therapeutic options available to physicians and other clinicians has expanded. Solutions to pain disorders are still elusive but continued human and animal studies will help to further identify the biochemical and neurophysiological factors that influence pain. The future of pain management will likely involve multidisciplinary departments dedicated to finding treatments that manage pain. The need is great worldwide for management of pain and there are still many facets of pain management that need to be explored.

Faced with intensifying competition and increasingly price sensitive markets, manufacturers in the area of pain management therapeutics are trying to differentiate their products to avoid price competition and to increase profits. However, there are a number of issues and trends that have a direct influence on this market and the manufacturer’s ability to successfully operate in the market. A keen awareness of all facets of the industry including barriers will enable manufacturers to effectively challenge these issues and formulate plans to reduce or eliminate barriers in the treatment of pain.

The driving forces for this market include growth and aging of the global population, new products and technology, and increasing interest in multidisciplinary approaches to pain management.

This report, The World Market for Pain Management Drugs and Devices, provides market estimates and forecasts for the following therapeutic categories:

  • Burn Pain
  • Cancer Pain
  • Dental/Facial Pain
  • Migraine Headache Pain
  • Musculoskeletal Pain
  • Neuropathic Pain
  • Obstetrical Pain
  • Pediatric Pain
  • Surgical and Trauma Pain

This report details the various categories of top prescription pain management drugs, describes U.S., European, Japanese and other markets in each of the specific pain areas. The report also covers drug delivery methods, pain management devices, and alternate treatment modalities that are influencing the market. It further identifies major market factors, which are discussed, and a total market summary is presented.

The information and analysis presented in this report are based on extensive interviews with senior management of top companies and conference participants (business and clinical) in the pain management market. Background information was obtained from a comprehensive search of published literature and reports obtained from various government, business, medical trade, and international journals. Key information from published literature was used to conduct interviews with over 45 industry executives and product managers to validate and obtain expert opinion on current and future trends in the pain management market. Interviews were also used to confirm and/or adjust market size estimates, as well as in formulating market projections.

All market data pertain to the world market at the manufacturers’ level. Data are expressed in current U.S. dollars. The base year for data was 2012. Historical data is provided for 2010 and 2011, and forecast data are provided for each of the years 2012 through 2017. Historical, base year, and forecast data are provided for each market segment. Market shares are provided for each market segment for the 2012 base year.

Top product revenues are considered for the report in each subsegment according to treatment use. Top products in each category represent approximately 80% of the total revenues for each subsegment. The total market reflects the total revenues of all top products in all of the individual categories, representing approximately 80%-90% of the total prescription pain management pharmaceuticals and pain management devices.

As part of the study the following competitors are profiled:

  • Abbott Laboratories
  • Actavis, Inc (formerly Watson Pharmaceuticals, Inc.)
  • AstraZeneca plc.
  • Baxter International, Inc.
  • BioDelivery Sciences International (BDSI)
  • Boehringer Ingelheim
  • Boston Scientific
  • Bristol-Myers Squibb Company
  • DepoMed
  • DURECT Corporation
  • Eli Lilly & Co.
  • Endo Health Solutions Inc
  • GlaxoSmithKline plc
  • Grunenthal Group
  • Medtronic, Inc.
  • Merck & Co.
  • Novartis
  • Pain Therapeutics, Inc
  • Pfizer, Inc
  • Purdue Pharma
  • QRx Pharma
  • Sanofi
  • St. Jude Medical, Inc
  • TEVA Pharmaceuticals Industries, Ltd
  • The Medicines Company
  • Valeant Pharmaceuticals International, Inc.
  • Zogenix, Inc.

Table of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

Introduction

Scope and Methodology

Size and Growth of the Market

Issues and trends

Leading Competitors

CHAPTER TWO: INTRODUCTION AND OVERVIEW

Definition of Pain

Magnitude of Pain

Physiology of Pain

Transduction

Transmission

Pain Pathways

Types of Pain

Measurement of Pain

Treatment Modalities—Pharmacologic Management

Analgesic Ladder

Step I Drugs

Step II Drugs

Step III Drugs

Recommended Drug and Route

Administration Routes

Titration

Treatment Modalities—Non-pharmacologic Management

Cognitive-Behavioral Therapies

Multidisciplinary Pain Management

Demographics

CHAPTER THREE: TREATMENT MARKETS AND FORECASTS

Burn Pain

Overview of Top Products

Opiate Agonists—Natural Alkaloids

Opiate Agonists—Semisynthetic Analogs

Opiate Agonists—Synthetic Compounds

Market Size and Growth

Markets by Region

Cancer Pain

Breakthrough Cancer Pain

Overview of Top Products

Opiate Agonists- Natural Alkaloids

Opiate Agonists-Semisynthetic Analogs

Opiate Agonists- Synthetic Compounds

Phenylpiperdine Compounds

New and/or Innovative Products

Market Size and Growth

Markets by Region

Dental/Facial Pain

Overview of Top Products

Opiate Agonists- Natural Alkaloids

Opiate Agonists-Semisynthetic Analogs

Opiate Agonists- Synthetic Compounds

Opiate Agonist-Antagonists

Centrally-acting Synthetic Analgesic Compounds

New Products

Market Size and Growth

Markets by Region

Migraine Headache Pain

Overview of Top Products

Selective Serotonin Agonists

New and/or Innovative Products

Market Size and Growth

Markets by Region

Musculoskeletal Pain

Overview of Top Products

Phenylpiperidine Compounds

Cox-2 Inhibitors

Non-steroid Anti-inflammatory Drugs

Opioid Agonists- Natural Alkaloids

Hyaluronate Sodium Derivative

New and/or Innovative Products

Market Size and Growth

Markets by Region

Neuropathic Pain

Overview of Top Products

Antiseizure Drugs

Opiate Agonists- Natural Alkaloids

Opiate Agonists-Semi-Synthetic Analogs

Phenylpiperidine Compounds

New and/or Innovative Products

Market Size and Growth

Markets by Region

Obstetrical Pain

Overview of Top Products

Opiate Agonists—Synthetic Compounds

Opiate Agonist—Antagonists

Centrally Acting Synthetic Analgesic Compounds

Phenylpiperidine Compounds

Market Size and Growth

Markets by Region

Pediatric Pain

Overview of Top Products

Opiate Agonist-Antagonists

Indole Analogs

Opiate Agonists-Semisynthetic Analogs

Opiate Agonists- Natural Alkaloids

Market Size and Growth

Markets by Region

Surgical and Trauma Pain

Overview of Top Products

Opiate Agonists—Natural Alkaloids

Opiate Agonists—Semisynthetic Analogs

Opiate Agonists—Synthetic Compounds

Opiate Agonist—Antagonists

Centrally Acting Synthetic Analgesic Compounds

New and/or Innovative Product Approvals

Market Size and Growth

Markets by Region

CHAPTER FOUR: DRUG DELIVERY

Oral Drug Delivery

Parenteral Drug Delivery

Transdermal

Patient Controlled Analgesia

Intrathecal Implants

Electrotransport Drug Delivery

CHAPTER FIVE: PAIN MANAGEMENT DEVICES

Transcutaneous Electrical Nerve Stimulators

Table of Contents v

Neuromuscular Stimulators

Spinal Cord Stimulators and Peripheral Nerve Stimulators

PCAs and Intrathecal Pain Pumps

Other Miscellaneous devices

Cranial Electrotherapy Stimulation

Electrothermal and Electromagnetic Therapy

Thermography

Market Size and Growth

Markets by Region

CHAPTER SIX: ALTERNATE TREATMENT MODALITIES

Acupuncture

ETPS Neuropathic Acupuncture

Low Level Laser Light Therapy

Biofeedback

Relaxation

Music and Pain Relief

Wave Therapy

Acupressure

Massage Therapy

Natural Supplements in Pain Management

Bioelectromagnetism

Radiofrequency Technology

Cryoablation

CHAPTER SEVEN: ISSUES AND TRENDS

Overview

Barriers to Cancer Pain Management

Education

Chronic Pain and Work

Managed Care Pain Management

The Fifth Vital Sign

Use of Psychopharmacology in Chronic Pain

Use of Botulinum Neurotoxin

Research and Development

Table of Contents vi

Dyloject

Levadex

MoxDuo IR

Naproxcinod

Pennsaid 2%

Posidur

Remoxy

Zelrix

Zohydro ER

ARC-4558

BEMA Buprenorphine

NGX 1998

Sativex

ATx08-001

The Elderly

Oxycontin Issues

Constant Pain Phenomenon

Tylenol and Liver Damage

Pain Medication Treatment Confusion

Transporter Discovery

Marijuana and Pain Control

Abuse-Deterrent Painkillers

Drug Abuse and Pain Control

CHAPTER EIGHT: MARKET SUMMARY

Total Market Size and Forecast

Total Market Revenues by Region

Competitor Analysis

CHAPTER NINE: CORPORATE PROFILES

Abbott Laboratories

Actavis, Inc (formerly Watson Pharmaceuticals, Inc.)

AstraZeneca plc.

Baxter International, Inc.

BioDelivery Sciences International (BDSI)

Boehringer Ingelheim

Boston Scientific

Table of Contents vii

Bristol-Myers Squibb Company

DepoMed

DURECT Corporation

Eli Lilly & Co.

Endo Health Solutions Inc

GlaxoSmithKline plc

Grunenthal Group

Medtronic, Inc.

Merck & Co.

Novartis

Pain Therapeutics, Inc

Pfizer, Inc

Purdue Pharma

QRx Pharma

Sanofi

St. Jude Medical, Inc

TEVA Pharmaceuticals Industries, Ltd

The Medicines Company

Valeant Pharmaceuticals International, Inc.

Zogenix, Inc.

APPENDIX: COMPANY DIRECTORY

LIST OF EXHIBITS

CHAPTER ONE: EXECUTIVE SUMMARY

Summary Table: Total World Pain Management Market 2010-2017

Summary Figure: Total World Pain Management Market 2010-2017

CHAPTER TWO: INTRODUCTION AND OVERVIEW

Table 2-1: Most Commonly Used Pain Quality Descriptors

Table 2-2: Pharmacokinetics of Step I Analgesics by Product

Table 2-3: Step II Analgesics: Pharmacokinetics

Table 2-4: Step III Analgesics: Pharmacokinetics

Table 2-5: Worldwide Prevalence of Selected Pain Related Conditions (est. 2012)

CHAPTER THREE: TREATMENT MARKETS AND FORECASTS

Table 3-1: World Market for Burn Pain Management 2010-2017

Table 3-2: Regional Markets for Burn Pain Management 20010-2017

Figure 3-2: Regional Markets for Burn Pain Management 2010-2017

Table 3-3: World Market for Cancer Pain Management 2010-2017

Figure 3-3: World Market for Cancer Pain Management 2010-2017

Table 3-4: Regional Markets for Musculoskeletal Pain Management 2010-2017

Figure 3-4: Regional Markets for Musculoskeletal Pain Management 2010-2017

Table 3-5: The World Market for Dental/Facial Pain Management 2010-2017

Figure 3-5: The World Market for Dental/Facial Pain Management 2010-2017

Table 3-6: Regional Markets for Dental/Facial Pain Management 2010-2017

Figure 3-6: Regional Markets for Dental/Facial Pain Management 2010-2017

Table 3-7: World Market for Migraine Pain Management 2010-2017

Figure 3-7: World Market for Migraine Pain Management 2010-2017

Table 3-8: Regional Markets for Migraine Pain Management 2010-2017

Figure 3-8: Regional Markets for Migraine Pain Management 2010-2017

Table 3-9: World Market for Musculoskeletal Pain Management 2010-2017

Figure 3-9: World Market for Musculoskeletal Pain Management 2010-2017

Table 3-10: Regional Markets for Musculoskeletal Pain Management 2010-2017

Figure 3-10: Regional Markets for Musculoskeletal Pain Management 2010-2017

Table 3-11: World Market for Neuropathic Pain Management 2010-2017

Figure 3-11: World Market for Neuropathic Pain Management 2010-2017

Table 3-12: Regional Markets for Neuropathic Pain Management 2010-2017

Figure 3-12: Regional Markets for Neuropathic Pain Management 2010-2017

Table 3-13: World Market for Obstetrical Pain Management 2010-2017

Figure 3-13: World Market for Obstetrical Pain Management 2010-2017

Table 3-14: Regional Markets for Obstetrical Pain Management 2010-2017

Figure 3-14: Regional Markets for Obstetrical Pain Management 2010-2017

Table 3-15: The World Market for Pediatric Pain Management 2010-2017

Table 3-16: Regional Markets for Pediatric Pain Management 2010-2017

Figure 3-16: Regional Markets for Pediatric Pain Management 2010-2017

Table 3-17: World Market for Surgical and Trauma Pain Management 2010-2017

Table 3-18: Regional Markets for Surgical and Trauma Pain Management 2010-2017

Figure 3-18: Regional Markets for Surgical and Trauma Pain Management 2010-2017

CHAPTER FIVE: PAIN MANAGEMENT DEVICES

Table 5-1: World Market for Pain Management Devices 2010-2017

Figure 5-1: World Market for Pain Management Devices 2010-2017

Table 5-2: Regional Markets for Pain Management Devices 2010-2017

Figure 5-2: Regional Markets for Pain Management Devices 2010-2017

CHAPTER SIX: ALTERNATE TREATMENT MODALITIES

Table 6-1: Pain Management Supplements in Clinical Trials

CHAPTER SEVEN: ISSUES AND TRENDS

Table 7-1: Pain Management Products in Development 2012

CHAPTER EIGHT: MARKET SUMMARY

Table 8-1: Total World Pain Management Market 2010-2017

Figure 8-1: Total World Pain Management Market 2010-2017

Table 8-2: World Pain Management Market by Product Segment (Pain Type), 2010–2017

Table 8-3: Total Regional Markets for Pain Management 2010-2017

Figure 8-4: Total Regional Markets for Pain Management 2010-2017

Table 8-4: World Market for Top Pain Management Treatments Revenues and Segments of Participation by Major Areas of Participation 2012

Table 8-5: Revenues and Market Share by Company 2012 (some are estimated)

Figure 8-6: Market Share Percent by Company 2012

CHAPTER NINE: CORPORATE PROFILES

Figure 9-1: Abbott’s Financial Performance, 2010-2012

Figure 9-2: Actavis’ Financial Performance, 2010-2012

Figure 9-3: AstraZeneca’s Financial Performance, 2010-2012

Figure 9-4: Baxter International’s Financial Performance, 2010-2012

Figure 9-6: Bristol-Myers Squibb’s Financial Performance, 2010-2012

Figure 9-7: Eli Lilly’s Financial Performance, 2010-2012

Figure 9-8: Endo Health Solutions’ Financial Performance, 2010-2012

Figure 9-9: GlaxoSmithKline’s Financial Performance, 2010-2012

Figure 9-10: Grunenthal’s Financial Performance, 2010-2012

Figure 9-11: Johnson and Johnson’s Financial Performance, 2010-2012

Figure 9-12: Medtronic’s Financial Performance, 2010-2012

Figure 9-13: Merck’s Financial Performance, 2010-2012

Figure 9-14: Novartis’ Financial Performance, 2010-2012

Figure 9-15: Pfizer’s Financial Performance, 2010-2012

Figure 9-16: Sanofi’s Financial Performance, 2010-2012

Figure 9-17: St Jude’s Financial Performance, 2010-2012

Figure 9-16: Teva’s Financial Performance, 2010-2012

 

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