Description
Histology and cytology tests are essential for identifying cancer, inherited, infectious disease and other diseases. This report focuses on tissue and cell diagnostic assays and technologies, providing the world markets for histology and cytology diagnostics for the current market and forecasted to 2018. All of the technologies and applications discussed in this report share the characteristic that they start with tissue or cell specimens. Global revenues are provided, broken out type of technology, including:
- Digital Pathology
- Pap Smear
- HPV Tests
- Flow Cytometry
- Circulating tumor cells (CTCs)
- Hematology (cell assays)
- In situ hybridization (ISH)
- Immunohistochemistry (IHC)
- Stains [non-Pap]
- Traditional Histology
Along with standard technologies are now being applied in this field, including MS mass spectrometry, next-generation sequencing, CTCs, and others. Advanced products in tissue and cell testing are still under development.
A global report, revenues for the overall tissue diagnostics market are broken out by geographical region for 2013 and 2018, covering
- North America
- Europe
- Asia
- Rest of World
In the past, tissue and cell diagnostics work had been highly labor intensive and subjective in results. This is no longer the case. The procedures have been changed in some part by the introduction of automated processes and digital analysis, and the development of cancer gene and HPV molecular tests.
Tissue diagnostics is a rapidly growing market driven by growth in global HPV diagnostics, new precision cancer treatment techniques, and novel companion diagnostic tests for drugs. Flow cytometry platforms have been available for many years. From flow cytometry and slide preparation through analysis, all the way to result reporting, combined and automated solutions enable faster turn-around time while providing standardized results.
The report profiles key companies in the industry, including
- 20/20 GeneSystems, Inc.
- 3DHISTECH Ltd.
- Abbott Laboratories
- Abcam plc
- AB SCIEX (A Danaher Corporation company)
- Adaptive Biotechnologies Corporation
- AdnaGen GmbH (An Alere Company)
- Advanced Cell Diagnostics
- Affymetrix, Inc.
- Agena Bioscience Inc.
- Agendia BV
- Agilent Technologies Inc.
- Aurora Interactive
- AutoGenomics, Inc.
- Aviva BioSciences Corporation
- Beckman Coulter, Inc. (Subsidiary of Danaher Corporation)
- Becton Dickinson and Co. (BD)
- Biocare Medical, LLC
- Biocartis S.A.
- Bio-Rad Laboratories, Inc.
- Bruker Corporation
- Cancer Genetics, Inc.
- Canopus Bioscience Ltd.
- Caris Life Sciences
- CellaVision AB
- Dako A/S (An Agilent Technologies Company)
- Danaher Corporation
- DiaTech Oncology
- Elitech Group
- EMD Millipore (Merck Millipore)
- Enzo Biochem, Inc.
- Epic Sciences, Inc.
- Fluidigm Corporation
- GE Healthcare
- Hologic, Inc.
- HORIBA Medical
- Janssen Diagnostics
- Leica Biosystems Inc. (Part of Danaher Corporation)
- Leica Microsystems (A Danaher Company)
- LeucoDx Inc.
- Life Technologies Corporation (Acquired by Thermo Fisher Scientific Inc.)
- MDxHealth SA
- Olympus Group
- Omnyx
- Oxford Gene Technology
- Panagene Inc.
- PerkinElmer, Inc.
- Protea Biosciences Group, Inc.
- Qiagen N.V.
- QuanDx
- QuantuMDx Group
- Rarecells SAS
- Response Genetics, Inc.
- Rheonix, Inc.
- Roche Diagnostics
- Siemens Healthcare Diagnostics
- Ventana Medical Systems Inc. (Member of the Roche Group)
And many other companies…
Market analyses in this report cover world markets for tissue and cell diagnostics. However, the reader will find a bias toward the developed areas of the globe — North America, Japan and Western Europe, the areas in which most tissue and cell diagnostic testing is currently performed. The information presented is derived from publicly available information sources such as company reports and announcements, government reports and databases, medical organization reports, medical associations, and other publications. The analysis is based on the author’s industry knowledge combined with literature searches and discussions with industry professionals and experts in the areas of point-of-care tests, decentralized healthcare and healthcare economics.
Table of Contents
ONE: EXECUTIVE SUMMARY
Overview
Scope and Methodology
Market Overview
Future Prospects in the Tissue and Cell Diagnostics Market
TWO: INTRODUCTION
Overview of Tissue and Cell Diagnostics
Histology and Cytology
Tissue and Cell Diagnostics
Point-of-View
THREE: TISSUE AND CELL ANALYSIS TECHNOLOGIES
Types of Specimens
Microscopy
Cell-Based Assays; Cellular Imaging Systems and High Content Screening (HCS)
Hematology Analyzers
Stains
Antibody-Based Technologies
Immunohistochemistry (IHC)
Flow Cytometry
Chromosome Analysis (Karyotyping)
Molecular Diagnostic Analysis of Tissues and Nucleic Acid from Tissues
Fluorescence In Situ Hybridization (FISH) and Chromogenic In Situ Hybridization (CISH)
Polymerase Chain Reaction (PCR) to Detect Biomarkers in Tissue Specimens
Analysis of Gene Expression Patterns (“Gene Signatures”)
Next Generation Sequencing
Tissue Microarrays
Circulating Tumor Cells (CTCs)
Digital Pathology and Image Cytometry
Histology Laboratory Automation
Mass Spectrometry – Imaging and Analysis of DNA
FOUR: TISSUE AND CELL DIAGNOSTICS APPLICATIONS
Research, Drug Discovery and Development
In Vitro Diagnostics
FIVE: DISEASE APPLICATIONS – TISSUE AND CELL DIAGNOSTICS
Cancer
Cancer Screening – Pap Smear and Human Papillomavirus (HPV) Testing
Diagnosis of Cancer
Pharmacodiagnostics
Prenatal Testing
Other Disease Applications of Tissue and Cell Diagnostics
SIX: DEALS – TISSUE AND CELL DIAGNOSTIC COMPANIES
Investments and Financing Agreements for Tissue and Cell Diagnostic Companies
Agreements with Other Companies
Acquisitions of Tissue and Cell Diagnostics Companies
Selected Other Agreements
SEVEN: TISSUE/CELL DIAGNOSTICS – MARKET DRIVERS AND CHALLENGES
Tissue/Cell Diagnostics Market Drivers
Issues and Hurdles Faced by Companies Selling to the Research Market
Issues and Hurdles Faced by In Vitro Diagnostic Companies
Increasing Numbers of Tests on Small Biopsy Specimens
Future Prospects
EIGHT: MARKET ANALYSIS
Tissue and Cell Diagnostics Market by Technology
Tissue and Cell Diagnostics Market by Geographical Distribution
Tissue and Cell Diagnostics Market by Disease Indication
Tissue and Cell Diagnostics – Proprietary Tests from Companies with CLIA-Certified
Laboratories
Analysis of Tissues and Cells in the Life Sciences
Prospects for Growth of the Tissue and Cell Diagnostics Market
NINE: COMPANY PROFILES: COMPANIES MARKETING OR DEVELOPING TISSUE DIAGNOSTIC PRODUCTS OR SERVICES
20/20 GeneSystems, Inc
3DHISTECH Ltd
Abbott Laboratories
Recent Revenue History
Company Overview (Focusing on Diagnostics, Especially Immunoassays)
Abcam plc
Recent Revenue History
Company Overview
AB SCIEX (A Danaher Corporation Company)
Adaptive Biotechnologies Corporation
Adnagen GmbH (An Alere Company)
Advanced Cell Diagnostics
Affymetrix, Inc.
Recent Revenue History
Company Overview (Focusing on Proteomics Activities)
Agena Bioscience Inc.
Agendia NV
Agilent Technologies Inc.
Recent Revenue History
Company Overview
Amoy Diagnostics Co., Ltd.
ANGLE plc
ApoCell, Inc.
Apogee Flow Systems Ltd.
Apollo PACS, Inc.
Applied Cytometry
Applied Spectral Imaging, Inc.
Arbor Vita Corporation
Asuragen, Inc.
Diagnostic Products
Clinical Lab
Genomic Services
Companion Diagnostics
Aurora Interactive
AutoGenomics, Inc.
Aviva BioSciences Corporation
Beckman Coulter, Inc. (Subsidiary of Danaher Corporation)
Recent Revenue History
Company Overview
Hematology
Flow Cytometry
Becton, Dickinson and Company (BD)
Recent Revenue History
Company Overview
Biocare Medical, LLC
Biocartis SA
BioCEP Ltd
Biocept, Inc.
BioDot Inc.
BioFluidica, Inc
BioGenex
BioMarker Strategies
bioMérieux SA
Recent Revenue History
Company Overview
BioMosaics Inc.
Bio-Rad Laboratories, Inc.
Recent Revenue History
Company Overview
Bio SB
BioTek Instruments, Inc.
bioTheranostics (A bioMérieux Company)
BioView Ltd.
Bruker Corporation
Recent Revenue History
Company Overview
Cancer Genetics, Inc.
Recent Revenue History
Company Overview
Canopus Bioscience Ltd.
Caris Life Sciences
Carl Zeiss AG
Carl Zeiss Microscopy GmbH
Recent Revenue History
Company Overview
Castle Biosciences Inc.
CCC Diagnostics, LLC
CDx Diagnostics
Celerus diagnostics, Inc.
CellaVision AB
CellTraffix, Inc.
Cellular Dynamics International
Celula, Inc.
Cernostics
Cirdan Imaging Ltd
Cisbio Bioassays
Clarient Diagnostic Services, Inc. (A GE Healthcare Company)
Clearbridge BioMedics
Clontech Laboratories, Inc (Member of the Takara Bio Group)
CombiMatrix Corporation
Recent Revenue History
Company Overview
Creatv MicroTech, Inc.
CymoGen Dx, LLC (Being Acquired by Biocare Medical, LLC)
Cynvenio Biosystems, Inc.
Cytek Development Inc.
CytoTrack ApS
Dako A/S (An Agilent Company)
Recent Revenue History
Company Overview
Danaher Corporation
Recent Revenue History
Company Overview
Definiens AG
DiaCarta Inc.
DiaTech Oncology
DiscoveRx Corporation
ELITech Group
EMD Millipore (Merck Millipore)
Recent Revenue History
Company Overview
Enzo Biochem, Inc
Enzo Life Sciences, Inc
Enzo Clinical Labs, Inc.
Recent Revenue History
Company Overview
Epic Sciences, Inc.
Fluidigm Corporation
Recent Revenue History
Company Overview
Fluxion Biosciences, Inc.
Foundation Medicine, Inc.
Recent Revenue History
Company Overview
GE Healthcare
Recent Revenue History
Company Overview
GeneCentric Diagnostics, Inc.
Genomic Health, Inc.
Recent Revenue History
Company Overview
HemoGenix
HistoGeneX
Hologic, Inc.
Recent Revenue History
Company Overview
HORIBA Medical
Recent Revenue History
Company Overview
HTG Molecular Diagnostics
Huron Technologies International Inc.
Icellate AB
Ikonisys, Inc.
ImaBiotech SAS
ImaBiotech Corp
IMMCO Diagnostics, Inc. (A Trinity Biotech Company)
IncellDx, Inc.
Indica Labs, Inc.
Insight Genetics, Inc.
IntelliCyt Corporation
Iris BioTechnologies Inc.
Recent Revenue History
Company Overview
Janssen Diagnostics
Janssen Diagnostics BVBA
Janssen Diagnostics, LLC (Oncology Diagnostics)
Leica Biosystems Inc. (Part of Danaher Corporation)
Leica Microsystems (A Danaher Company)
LeucoDx Inc.
Life Technologies Corporation (Acquired by Thermo Fischer Scientific Inc.)
Recent Revenue History
Company Overview
MDxHealth SA
Recent Revenue History
Company Overview
Metamark Genetics, Inc.
MetaSystems GmbH
MetaSystems Group, Inc.
Miltenyi Biotec GmbH
Molecular Devices, LLC (A Danaher Company)
MolecularMD Corporation
Monogram Biosciences (LabCorp Specialty Testing Group)
Multiplicom NV
Myriad Genetics, Inc.
Recent Revenue History
Company Overview
NanoString Technologies, Inc.
Recent Revenue History
Company Overview
Nikon Corporation
Nikon Instruments Inc.
Recent Revenue History
Company Overview
Nodality, Inc.
Norchip AS
Olympus Group
Recent Revenue History
Company Overview
Omnyx
OncoHealth Corp.
OncoPlex Diagnostics (OncoPlexDx)
Oxford Cancer Biomarkers Ltd
Oxford Gene Technology
Panagene Inc.
PerkinElmer, Inc.
Recent Revenue History
Company Overview
Quantitative Pathology Imaging and Analysis Systems
Cellular Imaging and Analysis Systems
Histological Analysis
Protea Biosciences Group, Inc.
Recent Revenue History
Company Overview
QIAGEN N.V.
Recent Revenue History
Company Overview
QuanDx
QuantuMDx Group
Rarecells SAS
Response Genetics, Inc.
Recent Revenue History
Company Overview
Rheonix, Inc.
Roche Diagnostics
Recent Revenue History
Company Overview
ScreenCell
Siemens Healthcare Diagnostics
Recent Revenue History
Company Overview
Sigma-Aldrich Corporation
Recent Revenue History
Company Overview
Silicon Biosystems
Sony Biotechnology Inc.
Span Diagnostics Ltd.
Sysmex Corporation
Recent Revenue History
Company Overview
TeloVISION, LLC
Theranostics Health Inc.
Thermo Fisher Scientific, Inc.
Recent Revenue History
Company Overview
Ventana Medical Systems, Inc. (Member of the Roche Group)
Veracyte, Inc.
Recent Revenue History
Company Overview
Vitatex Inc.
WaveSense, Inc.
