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Vaccines 2014: World Market Analysis with Forecasts to 2020, Key Players, Trends, Pediatric and Adult Segments (Influenza, Cervical Cancer, Combinations, Hepatitis, Pneumococcal, MMR, Varicella, Poliovirus , HIB, Others)

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SKU: KLI5232511 Categories: Pharmaceuticals Market Research, Vaccines Market Reports Pages: 240
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Description

Vaccines 2014: World Market Analysis, Key Players, Trends, Pediatric and Adult Segments

The global market for human vaccines experienced strong growth through 2013 with the introduction of new vaccines. These new products and other trends are well-covered in Vaccines: The World Market. The Kalorama information report examines the global market for vaccines, covering specifically commercialized vaccines and developmental vaccines for diseases that are already vaccine-preventable.

Vaccination protects not only individuals, but also entire communities from diseases spread by person-to-person transmission. The high growth rates and successful launch of several recent products have kept interest in the global vaccine market high. This report investigates the changes vaccine manufacturers have undergone in the past year, providing world market analysis, identifying the key players, and outlining critical trends in this fast-changing industry.

Included in this report are current market size and forecasts to 2020 for the following vaccines:

Pediatric Vaccines:

  • Pneumococcal
  • Combinations
  • Varicella
  • MMR
  • Poliovirus
  • Hepatitis
  • HIB
  • Other Pediatric

Adult Vaccines:

  • Influenza
  • Cervical Cancer
  • Hepatitis
  • Pneumococcal
  • Travel; DT; Misc.

The global market for vaccines experienced strong growth in many categories through 2013, declines in others, and this is expected to continue through the forecast period. Growth is being fueled by new product introductions and rising usage in all regions. Kalorama provides a global perspective in this report, including estimates of vaccine sales (pediatric and adult segments) in the following regions:

  • U.S.
  • Rest of North Amer.
  • South America
  • Europe
  • Japan
  • India
  • China
  • Rest of World

Despite ongoing improvements in pediatric vaccination, it is estimated that at least two million children die each year from diseases that could have been prevented by already existing vaccines. This problem is most significant in low income countries, with the health disparity between rich and poor countries resulting in average life spans of about 77 and 52 years, respectively. In addition to this high death toll, millions more suffer disability and illness because they have not been immunized.

Adult immunization is an important, but frequently overlooked, part of patient care. Though vaccination programs typically focus on children, adults in industrialized countries are more likely to die as a result of vaccine-preventable diseases than are children. For example, vaccination can prevent about 50% of deaths from pneumococcal disease and 80% of deaths from influenza-related complications in the elderly. Pharmacoeconomic studies have demonstrated the value of influenza and pneumococcal vaccines; however, immunization rates for these diseases continue to be low in the elderly populations.

Key issues in the global vaccine market today include product safety, refusal to immunize, supply shortages, the use of vaccines to prevent pandemics and address bioterrorism, and innovations in vaccine delivery systems. The following issues are discussed in this report.

  • Vaccine Safety
  • Refusal to Immunize
  • Obesity
  • Post-Licensure Surveillance
  • The Future of Vaccine Safety
  • Vaccine Shortages
  • Preventing Pandemics
  • Project Bioshield Act
  • National Bio and Agro-Defense Facility
  • DNA Vaccination
  • Mucosal Delivery
  • Intranasal Delivery
  • Vaccine Patches
  • Vaccine Chips and Microneedles
  • Innovations in Vaccine Production
  • Nanoparticle Systems
  • Cloning

This report includes profiles of the key players in vaccines, including:

  • AlphaVax, Inc.
  • Bavarian Nordic A/S
  • Baxter Healthcare
  • Bharat Biotech
  • Crucell /Johnson & Johnson
  • Emergent biosolutions
  • GlaxoSmithKline
  • Medimmune
  • Merck & Co. Inc
  • Novartis
  • Sanofi Pasteur
  • Pfizer

Table of Contents

ONE: EXECUTIVE SUMMARY

THE GLOBAL VACCINES INDUSTRY

Scope and Methodology

Overview

Pediatric Preventative Vaccines

Adult Preventative Vaccines

The Market

Issues and Trends

TWO: INTRODUCTION TO VACCINES

A Brief History: The Development of Vaccines

The Immune Response

Mechanism of Action

Types of Vaccines

Attenuated (Weakened) Live Viruses

Killed (Inactivated) Viruses

Toxoid Vaccines

Genetically Engineered/Modified Vaccines

Vaccine Approval Process

THREE: PEDIATRIC PREVENTIVE VACCINES

Introduction

Childhood Immunization in the United States

Childhood Immunization Rates

Challenges to the Vaccine Delivery System

The Effect of U.S. Healthcare Reform

Recommended Childhood Immunization Schedule

State Immunization Recommendations

United Nations Initiatives

Pediatric Vaccine Products

BCG

Diphtheria, Tetanus, Pertussis, Hepatitis B and Polio

Haemophilus Influenzae Type B

Hepatitis A

Measles, Mumps and Rubella

Meningococcal Disease

Pneumococcal Conjugate

Rotavirus

Varicella

Pediatric Vaccines in Development

Cost of Vaccines in the United States

The World Market for Pediatric Preventive Vaccines

Total Market Size and Forecast

Hepatitis Vaccine Market

Haemophilus Influenzae Type B Vaccine Market

Measles, Mumps and Rubella Vaccines Market

Combination Vaccines Market

Pneumococcal Vaccine Market

Poliovirus Vaccine Market

Varicella Vaccines Market

Other Vaccines Market

FOUR: ADULT PREVENTIVE VACCINES

Introduction

Adult Vaccine-Preventable Diseases: Facts and Figures

Global Influenza Surveillance Program

U.S. Surveillance

Recommendations for Adult Immunizations

WHO International Health Regulations

Adult Vaccine Products

Cervical Cancer

Cholera

Diphtheria-Tetanus

Hepatitis

Influenza

Japanese Encephalitis

Pneumococcal Disease

Rabies

Shingles

Typhoid Fever

Yellow Fever

Adult Vaccines in Development

The World Market for Adult Preventive Vaccines

Total Market Size and Forecast

Cervical Cancer Market

Hepatitis Market

Influenza Vaccine Market

Travel, DT, and Miscellaneous Vaccine Market

FIVE: VACCINES MARKET SUMMARY

Trends Driving the Vaccines Market

Market Size and Forecast

United States

North America

South America

Europe

Japan

India

China

Rest of World

Vaccine Market Competitors

Pediatric Vaccines

Adult Vaccines

SIX: ISSUES AND TRENDS

Vaccine Safety

Refusal to Immunize

Obesity

Post-Licensure Surveillance

The Vaccine Injury Compensation Program

World Health Organization

Other Initiatives

The Future of Vaccine Safety

Vaccine Shortages

Preventing Shortages in the Developed Countries

Preventing Shortages in Developing Nations

Preventing Pandemics

U.S. National Vaccine Plan

Vaccines and Bioterrorism

Overview

Project Bioshield Act

National Bio and Agro-Defense Facility

Vaccine Treatment and Evaluation Units

Anthrax

Smallpox

DNA Vaccination

Innovations in Vaccine Delivery Systems

Mucosal Delivery

Intranasal Delivery

Vaccine Patches

Vaccine Chips and Microneedles

Innovations in Vaccine Production

Plants

Insects

Nanoparticle Systems

Cloning

SEVEN: COMPANY PROFILES

AlphaVax, Inc.

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Bavarian Nordic A/S

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Baxter Healthcare

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Bharat Biotech

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Crucell /Johnson & Johnson

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Emergent biosolutions

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial

GlaxoSmithKline

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Medimmune

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Merck & Co. Inc

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Novartis

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Pfizer

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

Sanofi Pasteur

History and Lines of Business

Strategic Alliances

Vaccine Products

Financial Information

APPENDIX: COMPANY DIRECTORY

LIST OF EXHIBITS

TWO: INTRODUCTION TO VACCINES

Table 2-1: Impact of Vaccines in the 20th Century Annual Morbidity in the 20th Century vs 2012

Figure 2-1: Attenuated Virus Production

Table 2-2: Vaccine-Preventable Diseases, March 2014

Table 2-3: VAERS Table of Reportable Events Following Vaccination

THREE: PEDIATRIC PREVENTIVE VACCINES

Table 3-1: Total Number of Children Who Died from Diseases Preventable by Vaccines Recommended by the WHO 2012

Table 3-2: Immunization Profile of the United States: Population by Age Group, Number of Vaccine-Preventable Diseases Reported by

Disease 1990 – 2012

Table 3-3: Marketplace Enrollment as a Share of the Eligible Population,December 2013

Table 3-4: U.S. Recommended Immunization Schedule for Children

Ages 0 Through 18 Years, 2013

Table 3-5: Selected Pediatric Vaccines in Development, March 2014

Table 3-6: World Market for Pediatric Vaccines by Type (Hep, HiB, MMR,Combinations, Pneumococcal, Polio, Varicella, Others) 2011-2020

Figure 3-1: Market Share of Pediatric Vaccines by Type 2013

Figure 3-2: Market Share of Pediatric Vaccines, by Type 2020

Table 3-7: World Market for Pediatric Vaccines by Region (U.S., North America, South America, EU, Japan, India, China, Rest of World) 2011-2020

Table 3-8: World Pediatric Hepatitis Vaccine Market 2011-2020

Table 3-9: World Hib Vaccine Market, 2011-2020

Table 3-10: World MMR Vaccines Market 2011-2020

Table 3-11: World Combination Vaccines Market 2011-2020

Table 3-12: World Pediatric Pneumococcal Vaccine Market 2011-2020

Table 3-13: World Poliovirus Vaccine Market 2011-2020

Table 3-14: World Varicella Vaccine Market 2011-2020

Table 3-15: World Pediatric Other Vaccines Market 2011-2020

FOUR: ADULT PREVENTIVE VACCINES

Table 4-1: Universal Adult Immunization Schedule 2013

Table 4-2: Summary of Recommendations for Adult Immunization

Table 4-3: Initiatives to Require HPV Vaccination by U.S. State, 2014

Figure 4-1: U.S. Flu Season Severity from 2002 to 2013

Table 4-4: WHO Pandemic Classification Schedule

Table 4-5: Selected Adult Preventive Vaccines in Development, 2014

Table 4-6: World Market for Adult Preventive Vaccines by Type (Hepatitis,Influenza, Pneumococcal, Travel/DT/Misc.), 2011-2020

Figure 4-2: Market Share of Adult Vaccines, by Type, 2013

Figure 4-3: Market Share of Adult Vaccines, by Type, 2020

Table 4-7: World Market for Adult Vaccines by Region (U.S., North America,South America, EU, Japan, India, China, Rest of World) 2011-2020

Table 4-8: World Cervical CancerVaccine Market 2011-2020

Table 4-9: World Hepatitis Vaccine Market 2011-2020

Table 4-10: World Influenza Vaccine Market 2011-2020

Table 4-11: 2013 Estimated Population by Region and Selected Age Group

Table 4-12: World Pneumococcal Vaccine Market 2011-2020

Table 4-13: World Travel; Diphtheria-Tetanus; Miscellaneous Vaccines Market 2011-2020

FIVE: VACCINES MARKET SUMMARY

Figure 5-1: Sales Growth of Vaccines vs. Pharmaceuticals 2011-2020

Figure 5-2: World Market for Vaccines by Type 2011-2020

Table 5-1: The World Vaccines Market by Vaccine Type 2011-2020

Figure 5-3: World Market for Vaccines Share by Type, 2011

Figure 5-4: World Market for Vaccines Share by Type, 2015 and 2020

Table 5-2: The World Vaccines Market by Region 2011-2020

Table 5-3: Major Manufacturers’ Shares of the World Vaccine Market, 2013

Figure 5-5: 2013 World Vaccines Market Share, by Leading Competitors

Table 5-4: Major Manufacturer’s Shares of the World Pediatric Vaccine Market 2013

Figure 5-6: Market Share of Pediatric Vaccines Market, 2013

Table 5-5: Major Manufacturer’s Shares of the World Adult Vaccine Market 2013

Figure 5-7: Market Share of Adult Vaccines Market 2013

SEVEN: COMPANY PROFILES

Figure 7-1: AlphaVax Product Pipeline, March 2014

Figure 7-2: Bharat Biotech’s Product Pipeline, March 2014

Figure 7-3: Crucell’s Product Pipeline, March 2014

Figure 7-4: Emergent Bioslutions’ Product Pipeline, March 2014

Figure 7-5: Sanofi Pasteur’s Product Pipeline, March 2014

 

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