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Growth Factors: Indications, Products, and Markets

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SKU: KLI894210 Category: Pharmaceuticals Market Research Pages: 160
  • Description
  • Table of Contents
  • Latest reports

Description

Growth factors are gene products that play important roles in the regulation of cell division and tissue proliferation. Generally, the binding of a growth factor to its receptor initiates or, in some cases, blocks the ability of cells to divide and multiply. The nature and mode of action of these substances have made them of great interest in various therapeutic areas for which efficacy and specificity must go hand in hand.

This report analyzes the world markets for growth factors, focusing on the current and future markets for drugs used to promote the growth of tissue, organs, and blood vessels as well as those used in adjunctive cancer therapy, hepatitis C, and other indications.

Market forecasts are based on an examination of current market conditions and on investigations into the development of new products by key companies. This information is also weighted with the projected timing and the probability of receiving FDA and other regulatory approval to market products. Data points include estimates of global market size and growth for blood and tissue growth factors; competitive market share for categories such as erythropoietins, colony-stimulating factors, interleukins, interferons, wound growth factors, and neurotrophic growth factors; and geographic breakdown for four world regions.

In addition, the report generally reviews the nature and direction of research and profiles several companies involved in marketing or developing such products in the field, including Amgen, Chiron, Genentech, Johnson and Johnson, Stryker Biotech, and Wyeth, among others.

Interviews conducted with company executives, clinicians, researchers, and public health officials form the basis of the conclusions. In addition, information was gathered from company product literature and other corporate brochures and documents, as well as information found in the scientific literature, trade press, government databases, and regulatory filings.

Table of Contents

CHAPTER ONE: EXECUTIVE SUMMARY

Growth Factor Types

  • Blood Growth Factors
  • Erythropoietin
  • Colony stimulating factors
  • Cytokines
  • Tissue Growth Factors
  • Platelet-derived growth factor
  • Epidermal growth factor
  • Transforming growth factor-â
  • Transforming growth factor-á
  • Keratocyte growth factor
  • Insulin-like growth factor-I
  • Neurturin
  • Hepatocyte growth factor
  • Vascular endothelial growth factor
  • Fibroblast growth factors

Key Established Indications

  • Blood Growth Factors
  • Adjunctive Cancer Therapy
  • Hepatitis C
  • Condylomata Acuminata
  • Multiple Sclerosis
  • Osteopetrosis
  • Neutropenia
  • Tissue Growth Factors
  • Diabetic Foot Ulcers
  • New Bone Formation
  • Wound Care
  • Thrombocytopenia

Key Emerging Indications for Growth Factors

  • Oral Mucositis
  • Diabetic Neuropathy
  • Neurological Disorders
  • Ophthalmology
  • Muscle Atrophy
  • Wound Care
  • Tissue Growth
  • Kidney Disease
  • Orthopedics
  • Cardiovascular Disease
  • Bone Disease-Defects-Repair

Major Market Players

  • Blood Growth Factors
  • Tissue Growth Factors

Issues Driving the Market

Worldwide Market Forecast Summary

  • Blood Growth Factors
  • Tissue Growth Factors

Scope and Methodology

CHAPTER TWO: INTRODUCTION

The Need for Growth Factors

Growth Factors Defined

Blood Growth Factors

  • Erythropoietins
  • Colony Stimulating Growth Factors
  • The Interleukins
  • The Interferons

Tissue Growth Factors

  • Wound Healing Growth Factors
  • Platelet Derived Growth Factor
  • Keratocyte Growth Factor
  • Epidermal Growth Factor
  • Vascular Endothelial Growth Factor
  • Neurotrophic Growth Factors
  • Fibroblast Growth Factors
  • Insulin-Like Growth Factor
  • Musculoskeletal and Connective Tissue Growth Factors

Market Drivers

  • Population Growing
  • Potential for Serious Disease Increases
  • Epidemiologic Data and Demand Analysis
  • Adjunctive Cancer Therapy
  • Hepatitis C
  • Kidney/Renal Disease
  • Diabetic Neuropathy
  • Oral Mucositis
  • Stroke
  • Parkinson’s Disease
  • Alzheimer’s Disease
  • Atrophy
  • Macular Degeneration
  • Cardiovascular/Vascular Disease
  • Thrombocytopenia
  • Bone Repair
  • Wound Care
  • Tissue Engineering

Challenges Facing Developers

  • Biologics Issues Hurdle
  • Importance of Process Control

CHAPTER THREE: RESEARCH TRENDS

In the Pipeline

Specific Research Highlights

  • Blood Vessel Growth
  • Blood Vessel Cells
  • Cartilage Formation
  • Disease-Fighting Cells
  • Skin Treatment
  • Stroke Therapy
  • Sarcopenia
  • Parkinson’s Disease

CHAPTER FOUR: THE MARKET

Overall Forecasts and Trends

Products on the Market

  • Research Products

Market Players and Product Share

  • Erythropoietins
  • Colony Stimulating Factors
  • Interleukins
  • Interferons
  • Wound Growth Factors
  • Neurotrophic Growth Factors

Worldwide Market Forecast for Growth Factors

  • Established Blood Growth Factor Markets
  • Erythropoietins
  • Colony Stimulating Factors
  • The Interleukins
  • The Interferons
  • Established Tissue Growth Factor Markets
  • Wound Healing Growth Factors
  • Neurotrophic Growth Factors
  • Geographical Forecasts

CHAPTER FIVE: COMPANY PROFILES

  • Advanced Tissue Sciences
  • Amgen Inc.
  • Anika Therapeutics Inc.
  • Biomimetic Pharmaceuticals Inc.
  • Biosurface Engineering Technologies Inc.
  • Boston Life Sciences Inc.
  • Ceregene Inc.
  • Chiron Corp.
  • CuraGen Corp.
  • Curis Inc.
  • Eyetech Pharmaceuticals Inc
  • FibroGen Inc.
  • Genentech Inc.
  • GenSci Regeneration Sciences Inc.
  • GenVec Inc.
  • Human Genome Sciences
  • Insmed Inc.
  • Johnson & Johnson
  • Orquest Inc.
  • Protein Polymer Technology Inc.
  • Regeneron Pharmaceuticals Inc.
  • Sangamo BioSciences Inc.
  • Selective Genetics Inc.
  • Spectrum Pharmaceuticals Inc.
  • Stryker Biotech
  • Theratechnologies
  • Transition Therapeutics Inc.
  • Wyeth
  • ZymoGenetics Inc.

APPENDIX: COMPANY DIRECTORY

LIST OF EXHIBITS

Chapter One: Executive Summary

  • Table 1-1: World Market for Blood Growth Factors by Segment 2003 & 2007
  • Table 1-2: World Market for Tissue Growth Factors 2003, 2004, 2007

Chapter Two: Introduction

  • Table 2-1: World Population Distribution by General Age Group 1996, 2001, 2006, 2025, 2050
  • Table 2-2: Cancer Incidence and Deaths as a Percentage to Population by Selected Country/Region, 2001
  • Table 2-3: Global and U.S. Yearly Incidence of Skin Ulcers by Type
  • Figure 2-1: Global and U.S. Yearly Incidence of Skin Ulcers by Type

Chapter Three: Research Trends

Table 3-1: Selected Developmental Growth Factor-Based Therapies

Chapter Four: The Market

  • Table 4-1: World Market for Growth Factor Therapeutics Blood Growth Factors 2003-2007
  • Table 4-2: World Market for Growth Factor Therapeutics Tissue Growth Factors 2003-2007
  • Table 4-3: Growth Factor-Based Therapies on the Market
  • Table 4-4: Market Share for Leading Growth Factor Therapeutics Erythropoietins 2003
  • Table 4-5: Market Share for Leading Growth Factor Therapeutics Colony Stimulating Factors 2003
  • Table 4-6: Market Share for Leading Growth Factor Therapeutics Interleukins 2003
  • Table 4-7: Market Share for Leading Growth Factor Therapeutics Interferons 2003
  • Table 4-8: Market Share for Leading Growth Factor Therapeutics Wound Care Growth Factors 2005
  • Table 4-9: Market Share for Leading Growth Factor Therapeutics Neurotrophic Growth Factors 2005
  • Table 4-10: Total World Market for Blood Growth Factors 2003-2007
  • Table 4-11: World Market for Blood Growth Factors Distribution of Revenues by Factor Type 2003-2007
  • Table 4-12: World Market for Erythropoietins 2003-2007
  • Table 4-13: World Market for Colony Stimulating Factors 2003-2007
  • Table 4-14: World Market for Interleukins 2003-2007
  • Table 4-15: World Market for Interferons 2003-2007
  • Table 4-16: Total World Market for Tissue Growth Factors 2003-2007
  • Table 4-17: World Market for Tissue Growth Factors Distribution of Revenues by Factor Type, 2003-2007
  • Table 4-18: World Market for Wound Growth Factors 2003-2007
  • Table 4-19: World Market for Neurotrophic Growth Factors 2003-2007
  • Table 4-20: The Market for Erythropoietins by Geographical Region 2003-2007
  • Table 4-21: The Market for Colony Stimulating Factors by Geographical Region 2003-2007
  • Table 4-22: The Market for Interleukins by Geographical Region 2003-2007
  • Table 4-23: The Market for Interferons by Geographical Region 2003-2007
  • Table 4-24: The Market for Wound Growth Factors by Geographical Region 2003-2007
  • Table 4-25: The Market for Neurotrophic Growth Factors by Geographical Region 2003-2007

 

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