Description
The Market for Library Preparation and Target Enrichment for Next-Generation Sequencing
Market for Library Preparation and Target Enrichment for Next-Generation Sequencing (NGS) examines the current market, providing a comprehensive market summary, including NGS sample preparation revenues and growth rates for 2017-2022 and NGS sample preparation revenues by geographic region for 2017 (North America, Europe, Asia-Pacific, rest-of-world).
As NGS science continues to evolve, the report examines trends in the market, including the gradual acceptance and validation of clinical applications, China becoming a major player in the market, and the broad range of deals and acquisitions that have occurred. Further, the report covers information about many of the current products available in the market, including the hardware, reagents, kits, and other consumables.
The Market for Library Preparation and Target Enrichment for Next-Generation Sequencing presents the market shares of the library preparation and target enrichment market in 2017 by company ($M, %). Agilent, Illumina, and Thermo Fisher Scientific are among the market leaders profiled in the report.
The report contains discussion of key challenges in the market for library preparation and target enrichment products, and provides strategic recommendations moving forward.
Table of Contents
1: EXECUTIVE SUMMARY
INTRODUCTION
PRODUCT INTRODUCTIONS, INDICATIONS OF PRICE PRESSURE
STABILITY IN SEQUENCERS APPEARS TO BE CONTINUING
A PERIOD OF RAPID ADOPTION, BUT LOWER PRICES
HIGH LIKELIHOOD OF LONGER-TERM CHALLENGES
SIZE AND GROWTH OF THE MARKET
BACKGROUND
SCOPE AND METHODOLOGY
APPLICATIONS AND DEFINITIONS
2: LIBRARY PREP AND TARGET ENRICHMENT TRENDS
FALLING COSTS, IMPROVED OUTPUT, SMALLER AND SIMPLER
BROAD RANGE OF DEALS AND ACQUISITIONS
TECHNOLOGIES CONTINUING TO PUSH BOUNDARIES
CHINA BECOMING MAJOR PLAYER IN MARKET
MORE SYSTEMS STALLED OR CANCELLED
GRADUAL ACCEPTANCE AND VALIDATION OF CLINICAL APPLICATIONS
SUCCESS IN MICROBIOLOGY AND PATHOGEN DETECTION
REGULATORY TRENDS
GRADUAL BUT ROCKY PROGRESS WITH REGULATION AND REIMBURSEMENT
3: LIBRARY PREP AND TARGET ENRICHMENT PRODUCTS
Table 3-1: Selected Library Prep and Target Enrichment Products / Technologies Offered
4: NGS LIBRARY PREP AND TARGET ENRICHMENT MARKET REVENUES
REVENUES FORECAST
Figure 4-1: Cost of Sequencing a Genome
Table 4-1: NGS Sample Preparation Revenues, 2017-2022 ($M)
Table 4-2: NGS Sample Preparation Growth Rate, 2017-2022 (%)
Figure 4-2: NGS Sample Preparation Revenues, 2017-2022 ($M)
Figure 4-3: NGS Sample Preparation Growth Rate, 2017-2022 (%)
REVENUES BY REGION
Table 4-3: NGS Sample Preparation Revenues by Region, 2017 (N. America, Europe, Asia-Pacific, Rest-of-World) ($M)
Figure 4-4: NGS Sample Preparation Revenues by Region, 2017 (N. America, Europe, Asia-Pacific, Rest-of-World) (%)
ILLUMINA CONSUMABLES REVENUES
Table 4-4: Illumina Quarterly Consumables Revenues (2014-2018) ($M)
Figure 4-5: Illumina Quarterly Consumables Revenues (2014-2018) ($M)
Table 4-5: Illumina Consumables Shares (2012-2017) ($M)
Figure 4-6: Illumina 2012 Sequencing Consumables Share (%)
Figure 4-7: Illumina 2017 Sequencing Consumables Share (%)
Table 4-6: Illumina Consumables Growth Rates, 2013-2017 (%)
5: COMPETITIVE ANALYSIS
INTRODUCTION
Continued Growth and Technology Advances
Sequencer Battles Turn Somewhat Calm
LIBRARY PREPARATION AND TARGET ENRICHMENT MARKET SHARES
Table 5-1: Library Preparation and Target Enrichment Market Shares by Company, 2017 ($M, %)
Figure 5-1: Library Preparation and Target Enrichment Market Shares by Company, 2017 (%)
SMALLER COMPANIES EXPERIENCING MIXED SUCCESS
6: INTELLECTUAL PROPERTY AND LITIGATION
PACIFIC BIOSCIENCES AND OXFORD NANOPORE
SEVERAL NIPT COMPANIES FIGHTING
ARIOSA DIAGNOSTICS (ROCHE) FILES SUIT AGAINST SEQUENOM
NATERA SUES SEQUENOM; SEQUENOM SUES NATERA
VERINATA HEALTH AND STANFORD FILE AGAINST SEQUENOM
VERINATA HEALTH AGAINST ARIOSA AND LABCORP
ILLUMINA SUES ARIOSA DIAGNOSTICS FOR NIPT TEST
ILLUMINA SUES PREMAITHA HEALTH FOR NIPT TEST
SEQUENOM AND ILLUMINA SETTLE AND POOL PATENTS
SEQUENOM PETITIONS SUPREME COURT
ILLUMINA’S CONFLICTS WITH OXFORD NANOPORE
ENZO BIOCHEM BRINGS SUIT AGAINST NUMEROUS COMPANIES
454 (ROCHE) SUES ION TORRENT (THERMO FISHER)
RAINDANCE TECHNOLOGIES SUES 10X GENOMICS
10X GENOMICS’ DISPUTE WITH BIO-RAD
SEQUENOM SHAREHOLDER SUES OVER PRICE “CAPPING”
CLASS ACTION SHAREHOLDER LAWSUIT FILED AGAINST PACIFIC BIOSCIENCES
HELICOS’ PATENT INFRINGEMENT SUIT AGAINST PACBIO, LIFE TECHNOLOGIES, AND ILLUMINA
ILLUMINA’S TWO LAWSUITS AGAINST COMPLETE GENOMICS FOR INFRINGEMENT
LIFE TECHNOLOGIES AND ILLUMINA DISPUTE OVER AMPLIFICATION ON SOLID SURFACES
LIFE TECHNOLOGIES FILES INFRINGEMENT SUIT AGAINST PROMEGA
ENZO BIOCHEM DISPUTES SEQUENCING PATENTS
AZCO BIOTECH SUES QIAGEN AND INTELLIGENT BIO-SYSTEMS
INTELLIGENT BIO-SYSTEMS (QIAGEN) AND COLUMBIA UNIVERSITY SUE ILLUMINA FOR INFRINGEMENT
LABCORP’S ESOTERIX SUES LIFE TECHNOLOGIES
GENETIC TECHNOLOGIES SUES SEVERAL FIRMS FOR INFRINGEMENT OF HAPLOTYPE DETERMINATION TECHNIQUE
ILLUMINA SUES LIFE TECHNOLOGIES OVER ION TORRENT SYSTEMS
LIFE TECHNOLOGIES DEFEATS VISIGEN STAKEHOLDERS AFTER ARBITRATION
CATALYST ASSETS SUES LIFE TECHNOLOGIES FOR INFRINGEMENT
PATENT INTERFERENCE BETWEEN LIFE TECHNOLOGIES AND PACIFIC BIOSCIENCES
LADATECH SUES ILLUMINA OVER DNA AMPLIFICATION PATENT
ILLUMINA FILES ‘841 PATENT INFRINGEMENT SUIT AGAINST AFFYMETRIX
AFFYMETRIX AND ILLUMINA SETTLE CASE OVER ‘243, ‘432, ‘531, ‘365, AND ‘716
APPLIED BIOSYSTEMS AND ILLUMINA CLAIMS AND COUNTER-CLAIMS OVER SEQUENCING-BY-LIGATION BOTH UNSUCCESSFUL
7: LIBRARY PREP AND TARGET ENRICHMENT MARKET DEALS
Table 7-1: Recent Selected Significant Collaborations in the NGS Library Preparation and Target Enrichment Market
8: CORPORATE PROFILES
10X GENOMICS
AGILENT TECHNOLOGIES
- HOFFMANN-LA ROCHE AG
FLUIDIGM
ILLUMINA
NEW ENGLAND BIOLABS
OXFORD NANOPORE
PACIFIC BIOSCIENCES
QIAGEN
THERMO FISHER SCIENTIFIC
9: CHALLENGES AND STRATEGIC RECOMMENDATIONS
CHALLENGES
STRATEGIC RECOMMENDATIONS
