Description
Liquid biopsies are a set of minimally invasive diagnostic methods that analyze tumor-derived materials that can be found circulating in biological fluids, to provide information for the diagnosis, treatment, and monitoring of cancer.
This report, The World Liquid Biopsy Market, from Kalorama Information, contains up-to-date information and useful data points for business planning:
- Research vs. Clinical Liquid Biopsy
- The Market for Liquid Biopsy by Region
- The Market for Liquid Biopsy Market by Type of Analyte
- The Market for CTC-based Liquid Biopsy
- The Market for ctDNA-based Liquid Biopsy
- The Market for EV and Exosome-based Liquid Biopsy
- The Market for Multi-Analyte-based Liquid Biopsy
- The Market for Other Liquid Biopsy
- Liquid Biopsy Market by Type of Cancer (Breast, Lung, Colorectal, Ovarian, Prostate, Pan-Cancer, Other Cancer)
- Selected ctDNA-based Liquid Biopsy Tests in Development
- Selected Market-Available CTC-based Liquid Biopsy Tests, 2019
- Selected Liquid Biopsy Tests That Assess Multiple Analytes, 2019
While tissue biopsies and imaging techniques remain the current standards of care in the diagnosis of solid tumors, they have risks and limitations and limitations, some of which can be overcome by the use of liquid biopsy in clinical oncology, as an alternative or complementary technique to the current standards of care.
Liquid biopsy testing has many potential applications in aspects of clinical oncology, including:
- Early detection and diagnosis / screening
- Alternative testing method when tissue biopsy is difficult/impossible, or when the primary site of metastatic disease is unknown
- Therapy personalization and monitoring – by molecular characterization of a patient’s disease, clinicians can select the optimal course of therapy and monitor efficacy over time, as well as quickly react to adjust therapy should treatment resistance arise
- Disease monitoring – to observe disease progression, tumor evolution, residual disease, and early detection of recurrence
- Prognosis of disease
Table of Contents
Chapter One: Executive Summary
Introduction
Liquid Biopsy Technologies
Industry Structure
Liquid Biopsy Market Revenues and Forecast
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- Figure 1-1: Global Liquid Biopsy Market by Geographic Region, 2016 (%)
- Table 1-1: Global Liquid Biopsy Market Forecast by Region ($ millions), 2018-2023
- Figure 1-2: Global Liquid Biopsy Market Forecast by Region $ millions), 2018-2023
Chapter Two: Liquid Biopsy Technologies
Introduction
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- Table 2-1: Comparison of Tissue and Liquid Biopsy
Current Major Liquid Biopsy Technologies
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- Table 2-2: Advantages and Limitations of Major Liquid Biopsy Technologies
Chapter Three: Circulating Tumor DNA (ctDNA) Liquid Biopsy
Introduction
Advantages and Limitations of ctDNA in Liquid Biopsy
Current ctDNA-based Liquid Biopsy Tests
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- Table 3-1: Selected Market-Available ctDNA-based Liquid Biopsy Tests, 2019
- Biocartis
- Biocept
- Biodesix
- CellMax Life
- Circulogene
- Diacarta
- Epigenomics
- Foundation Medicine
- Guardant Health
- Inivata
- LungLife AI
- Myriad Genetics
- NeoGenomics
- OncoDNA
- Personal Genomic Diagnostics
- QIAGEN
- Resolution Biosciences
- Roche Diagnostics
- Sysmex-Inostics
ctDNA-based Liquid Biopsy Tests in Development
- Table 3-2: Selected ctDNA-based Liquid Biopsy Tests in Development
- Exact Sciences
- Freenome
- GRAIL
- Personal Genome Diagnostics
- Tempus
Chapter Four: Circulating Tumor Cells (CTCs) Liquid Biopsy
Introduction
Challenges in the Development of CTC-based Liquid Biopsy Tests
CTC-based Liquid Biopsy Tests
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- Table 4-1: Selected Market-Available CTC-based Liquid Biopsy Tests, 2019
- Adaptive Biotechnologies
- Biocept
- CellMax Life
- Epic Sciences
- GILUPI
- LungLife AI
- Menarini-Silicon Biosystems
- QIAGEN
CTC-based Liquid Biopsy Tests in Development
- Table 4-2: Selected CTC-based Liquid Biopsy Tests in Development, 2019
- ANGLE
- Epic Sciences
- Liquid Biotech USA
Chapter Five: Extracellular Vesicles and Other Liquid Biopsy
Introduction
Liquid Biopsy Tests Based on Extracellular Vesicles / Other Analytes
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- Table 5-1: Selected Market-Available Liquid Biopsy Tests based on Extracellular Vesicles / Other Analytes, 2019
- Biodexis
- Exosome Diagnostics
- Hologic
- MDxHealth
- Vermillion
Extracellular Vesicle/Other Analyte-based Liquid Biopsy Tests in Development
- Table 5-2: Selected Extracellular Vesicle/Other Analyte-based Liquid Biopsy Tests in Development, 2019
- Circulogene
- OncoCyte
- QIAGEN
- Resolution Biosciences
- VolitionRx
Chapter Six: Multi-Analyte Liquid Biopsy Tests
Introduction
Liquid Biopsy Tests Based on Multiple Analytes
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- Table 6-1: Selected Liquid Biopsy Tests That Assess Multiple Analytes, 2019
- Biocept
- Biodesix
- Foundation Medicine
- LungLife AI
- NeoGenomics
- OncoDNA
Multiple Analyte-based Liquid Biopsy Tests in Development
- Table 6-2: Selected Multi Analyte-based Liquid Biopsy Tests in Development, 2019
- Exact Sciences
- Freenome
- GRAIL
- LungLife AI
Chapter Seven: Liquid Biopsy Tests for Research Use Only
Introduction
Liquid Biopsy Tests for Research Use Only
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- Table 7-1: Selected Liquid Biopsy Tests for Research Use Only, 2019
- Agena Bioscience
- ANGLE
- DiaCarta
- Exosome Diagnostics
- Guardant Health
- Natera
- QIAGEN
Chapter Eight: Liquid Biopsy Industry Analysis
Introduction
Tiers of Competition
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- Table 8-1: Selected Participants in the Liquid Biopsy Market, 2019
Competitive Factors
Significant Market Trends
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- Table 8-2: Significant Trends in the Liquid Biopsy Market, 2019
- Personalized Medicine
- Increasing Global Life Expectancy
- New Liquid Biopsy Products
- Increasing Accessibility of Genetic Testing
- Figure 8-1: Laboratory Testing Sites ñ Tests Performed by Vendor vs. Testing Performed by Outside Labs (%)
- Regulatory Hurdles
- Third-Party Payor Coverage
- Demonstrated Clinical Utility
- Incidence Rates of Specific Cancers
Competitors No Longer in the Liquid Biopsy Market
- Table 8-3: Summary of Companies That Have Exited the Liquid Biopsy Market
Chapter Nine: Liquid Biopsy Market
Market Overview
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- Figure 9-1: Global Liquid Biopsy Diagnostics Market Estimate by Analyte, 2018 (%)
- Figure 9-2: Global Liquid Biopsy Diagnostics Market Estimate by Region, 2018 (%)
- Figure 9-3: Global Liquid Biopsy Market Estimate by Type of Use, (Research Use, Clinical Diagnostics Use) 2018 (%)
- Figure 9-4: Global Liquid Biopsy Market by Test Performance Model (In-House Labs, Outside Clinical Labs, Both Options Available) (%)
Market Forecast
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- Table 9-1: Global Liquid Biopsy Market Forecast by Region ñ North America, Europe, Asia Pacific, Rest of World, World ($ millions), 2018-2023
- Figure 9-5: Global Liquid Biopsy Market Forecast by Region ñ North America, Europe, Asia Pacific, Rest of World ( $ millions), 2018-2023
Chapter Ten: Market by Analyte
Circulating Tumor DNA
Chapter Eleven: Market by Application
Therapy Guidance and Monitoring
- Market Overview
- Revenue Forecast
- Table 11-1: Liquid Therapy for Therapy Guidance ($ millions), 2018-2023
Diagnosis/Screening
- Market Overview
- Revenue Forecast
- Table 11-2: Global Liquid Biopsy Market for Diagnosis and Screening ($ millions), 2018-2023
Disease Prognosis
- Market Overview
- Revenue Forecast
- Table 11-3: Global Liquid Biopsy Market for Disease Prognosis ($ millions), 2018-2023
Chapter Twelve: Market by Cancer Type
Breast Cancer
- Market Overview
- Revenue Forecast
- Table 12-1: Global Liquid Biopsy Market for Breast Cancer ($ millions), 2018-2023
Colorectal Cancer
- Market Overview
- Revenue Forecast
- Table 12-2: Global Liquid Biopsy Market for Colorectal Cancer ($ millions), 2018-2023
Lung Cancer
- Market Overview
- Revenue Forecast
- Table 12-3: Global Liquid Biopsy Market for Lung Cancer ($ millions), 2018-2023
Ovarian Cancer
- Market Overview
- Revenue Forecast
- Table 12-4: Global Liquid Biopsy Market for Ovarian Cancer ($ millions), 2018-2023
Prostate Cancer
- Market Overview
- Revenue Forecast
- Table 12-5: Global Liquid Biopsy Market for Prostate Cancer ($ millions), 2018-2023
Other Cancers
- Market Overview
- Revenue Forecast
- Table 12-6: Global Liquid Biopsy Market for Other Cancers ($ millions), 2018-2023
Pan-Cancer Tests
- Market Overview
- Revenue Forecast
- Table 12-7: Global Liquid Biopsy Market for Pan-Cancer Testing ($ millions), 2018-2023
Chapter Thirteen: Liquid Biopsy Company Profiles
Top Ten Companies in the Liquid Biopsy Market
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- Table 13-1: Top Ten Companies in the Liquid Biopsy Market
Adaptive Biotechnologies
Agena Bioscience, Inc.
ANGLE, plc
Biocartis Group NV
Biocept, Inc.
Biodesix
CellMax Life
Circulogene
DiaCarta, Inc.
Epic Sciences
Epigenomics AG
Exact Sciences
Exosome Diagnostics, Inc.
Foundation Medicine, Inc.
Freenome, Inc.
Genomic Health, Inc.
GILUPI GmbH
GRAIL
Guardant Health, Inc.
Hologic
Inivata
Liquid Biotech USA
LungLife AI (formerly Cynvenio Biosystems)
MDxHealth
Menarini-Silicon Biosystems, Spa
Myriad Genetics, Inc.
Natera, Inc.
NeoGenomics Laboratories, Inc.
OncoCyte Corporation
OncoDNA S.A.
Personal Genome Diagnostics
QIAGEN N.V.
- Cell-free DNA Technologies
- CTC Technologies
- Exosome and miRNA Technologies
Resolution Biosciences
Roche Diagnostics
Sysmex-Inostics, Inc.
Tempus
Vermillion, Inc.
VolitionRx
