Description
Downstream Bioprocessing Markets (Chromatography Columns and Resins, Membrane Adsorbers, Filtration Systems, Sensors)
Downstream processing, or bioprocessing, involves the recovery and purification of biosynthetic products, often pharmaceuticals, from natural sources. These sources may be animal or plant tissue or fermentation broth. It is an essential step in producing pharmaceuticals, such as antibiotics, hormones (insulin and human growth hormone), antibodies, and vaccines. Downstream Bioprocessing Markets analyzes the current and potential world market for components used in downstream processing, including the global downstream bioprocessing market, 2016-2021 ($ billions), in total and by the following market segments: chromatography columns and resins, membrane adsorbers, filtration, and sensors.
The report also provides data in total and by segment for the global downstream bioprocessing markets by geography, 2016-2021 ($ billions; US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW). As well as future markets, this report generally reviews the nature and direction of research.
ESI Ultrapure, GE Healthcare, Millipore, Natrix, Pall, Sartorius, and Thermo Fisher Scientific are among the downstream bioprocessing market companies profiled in the report.
Table of Contents
1: EXECUTIVE SUMMARY
OVERVIEW
Focus on Cost Effectiveness
Outsourcing Popular
Flexibility and More
Research Needed
- Table 1. World Market for Downstream Bioprocessing Components, 2016-2021 ($ billions)
METHODOLOGY
2: INTRODUCTION
DOWNSTREAM PROCESSING
- Table 2. The State of Downstream Bioprocessing
Important Roles
- Table 3. Key Roles of Downstream Bioprocessing
Safety and EfficacySTAGES OF DOWNSTREAM PROCESSING
- Table 4. Stages of Downstream Bioprocessing
Solid-Liquid SeparationIntracellular Product ReleaseProduct ConcentrationChromatography PurificationFormulationCHANGES IN PRODUCTION NATURE
- Table 5. Current Biopharmaceutical Product Mix
Innovation RequiredGlobalization ContinuesTHE NEED FOR OPERATIONAL EXCELLENCECOMPETITION GENERATING COST EFFICIENCIESDownstream ResistanceProcess IntensificationHigher TitersNew TechnologiesFlexibilityIntegration and AutomationContinuous ProcessingDEVELOPING RESEARCH AREASChromatographyResinsAlternative Processes for PurificationSpectroscopyFILTRATION TECHNOLOGIES ADVANCETangential FlowAutomatedGel Filtration ChromatographyPrecipitation AlternativeSlow Adoption of New TechnologiesOUTSOURCINGCore CompetenciesDriversIssuesThe Future
3: TRENDS AND DRIVERS
- Table 6. Key Trends in Downstream Bioprocessing
PROTEIN AMOLECULE ISSUESCHROMATOGRAPHY
- Table 7. Application of Single Use Technology Downstream (percentage of overall use)
STREAMLINING AND REDESIGNINGStreamlining NichesPURIFICATIONGREATER USE OF CONTRACT MANUFACTURERSPRODUCTION EFFICIENCYINTERNATIONALCANCER THERAPY PUSHCOLLABORATIONS AND INNOVATION
4: CHALLENGES
CHROMATOGRAPHYCONTINUOUS PROCESSINGTITERS AND COMPOSITIONEVOLVING CLARIFICATION AND PURIFICATION STRATEGIESCAPACITY BOTTLENECKSISOLATION OF PROTEINSEFFICIENCIESQUALITY BY DESIGNTALENT SHORTAGE
5: MARKET DEVELOPMENTS
COLLABORATION TO IMPROVE DOWNSTREAM BIOPROCESSING
START-UP ACQUISITION
PROMOTING PRE-PACKED COLUMNS
NEXT GENERATION COLUMNS
NEXT GENERATION AFFINITY LIGANDS
IMMUNOGLOBULIN FACILITY
BIOPROCESSING SERVICES
EXPANSION
ACQUISITION
SUPPLY DEAL
BIOCONJUGATION PROCESS
NEW STRUCTURED SUBSTRATES
NEW PROTEIN A CHROMATOGRAPHY RESIN
ENTERPRISE SOFTWARE INCREASES THROUGHPUT AND QUALITY
INVESTING IN PROTEIN EXPRESSION PLATFORM
6: MARKET LANDSCAPEOVERVIEWDRIVERS
- Table 8. Key Drivers of Downstream Bioprocessing
Expanding Therapies and MarketsMARKET ANALYSIS AND FORECASTSBiosimilarsGrowth and Emerging MarketsContinuous ProcessingGLOBAL MARKET FOR DOWNSTREAM BIOPROCESSING COMPONENTS
- Table 9. Downstream Components Bioprocessing Market Share by Vendor 2018 (%)
- Table 10. World Downstream Bioprocessing Markets, 2016-2021 ($ billions)
- Table 11. World Downstream Bioprocessing Markets by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
- Table 12. World Downstream Bioprocessing Markets by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Chromatography Columns and Resins
- Table 13. World Downstream Bioprocessing Chromatography Columns and Resins Markets, 2016-2021 ($ billions)
- Table 14. World Downstream Bioprocessing Chromatography Columns and Resins Markets by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
- Table 15. World Downstream Bioprocessing Chromatography Columns and Resins Markets by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Membrane Adsorbers
- Table 16. World Downstream Bioprocessing Membrane Adsorber Market, 2016-2021 ($ millions)
- Table 17. World Downstream Bioprocessing Membrane Adsorber Market by Geography, 2016-2021 ($ millions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
- Table 18. World Downstream Bioprocessing Membrane Adsorber Market by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Filtration Systems
- Table 19. World Downstream Bioprocessing Filtration Market, 2016-2021 ($ billions)
- Table 20. World Downstream Bioprocessing Filtration Market by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
- Table 21. World Downstream Bioprocessing Filtration Market by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
Sensors
- Table 22. World Downstream Bioprocessing Sensor Market, 2016-2021 ($ billions)
- Table 23. World Downstream Bioprocessing Sensor Market by Geography, 2016-2021 ($ billions) (US, Western Europe, Eastern Europe, APAC [China, Japan, S. Korea, India, Others], Latin America, ROW)
- Table 24. World Downstream Bioprocessing Sensor Market by Geography, 2017 (%) (US, Western EU, Eastern EU, APAC, ROW, SA)
7: CORPORATE PROFILES3M COMPANY, ST. PAUL, MN 55144, WWW.3M.COM/3M/EN_US/COMPANY-USABEC, BETHLEHEM, PA 18017, WWW.ABEC.COMALFA LAVAL, LUND, SWEDEN, WWW.ALFALAVAL.COMAVANTOR PERFORMANCE MATERIALS, CENTER VALLEY, PA 18034, WWW.AVANTORINC.COMBIA SEPARATIONS, AJDOVŠČINA, SLOVENIA, WWW.BIASEPARATIONS.COMBOEHRINGER INGELHEIM PHARMACEUTICALS, RIDGEFIELD, CT 06877, WWW.BIOXCELLENCE.COMBOSCH, STUTTGART, GERMANY, WWW.BOSCH.DE/EN/DOW, MIDLAND, MI, WWW.DOW.COMESI ULTRAPURE, CWMBRAN, TORFAEN, NP44 3XS, UK, WWW.ESIULTRAPURE.COMFINESSE SOLUTIONS, SANTA CLARA, CA 95054, WWW.FINESSE.COMFUJIFILM DIOSYNTH BIOTECHNOLOGIES, COLLEGE STATION, TX 77845, WWW.FUJIFILMDIOSYNTH.COMGE HEALTHCARE LIFE SCIENCES, MARLBOROUGH, MA 01752, HTTPS://WWW.GELIFESCIENCES.COM/ SOLUTIONS/BIOPROCESSING/PRODUCTS-AND-SOLUTIONS/DOWNSTREAM-BIOPROCESSINGGEA GERMANY DÜSSELDORF, 40468 DÜSSELDORF, GERMANY, WWW.GEA.COM/ENLONZA GROUP, BASEL, SWITZERLAND, WWW.LONZA.COMMILLIPORE, MILLIPORE SIGMA, BURLINGTON, MA 01803, WWW.EMDMILLIPORE.COMNATRIX SEPARATIONS, BURLINGTON, ONTARIO, L7L 6A8 CANADA, WWW.NATRIXSEPARATIONS.COMNORDSON MEDICAL, MARLBOROUGH, MA 01752, WWW.NORDSONMEDICAL.COMPALL BIOTECH, PORT WASHINGTON, NY 11050, HTTPS://BIOTECH.PALL.COMPARKER HANNIFIN, CLEVELAND, OH 44124, WWW.PARKER.COMREPLIGEN, WALTHAM, MA 02453, WWW.REPLIGEN.COMSARTORIUS AG, GOETTINGEN, GERMANY, WWW.SARTORIUS.COMTHERMO FISHER SCIENTIFIC, WALTHAM, MA 02451, HTTPS://WWW.THERMOFISHER.COM/US/EN/HOME/LIFE-SCIENCE/BIOPRODUCTION.HTMLW. L. GORE & ASSOCIATES, INC., NEWARK, DE 19711, WWW.GORE.COMWATSON-MARLOW FLUID TECHNOLOGY GROUP, FALMOUTH, TR11 4SZ UK, WWW.WATSON-MARLOW.COM
