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PCR Markets for Life Sciences Applications (Market by Type – qPCR, dPCR – Application – Pharmaceutical, General Research, and by Country and Region)

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SKU: KLI15618801 Category: Biotechnology Market Research Pages: 159
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Description

PCR Markets for Life Sciences Applications (Market by Type – qPCR, dPCR – Application – Pharmaceutical, General Research, and by Country and Region)

As part of its coverage of this market, Kalorama Information’s report provides:

  • The Market for Life Sciences PCR, 2017 to 2022
  • Application Market Segmentation of Pharmaceutical and General Medical Research 
  • Market Segmentation of qPCR and dPCR markets, 2017-2022
  • United States Life Sciences PCR Market, 2017-2022
  • European Life Sciences PCR Market, 2017-2022
  • Japanese Market for Life Sciences PCR, 2017-2022
  • China Market for Life Sciences PCR, 2017-2022
  • LATAM Market for Life Sciences PCR, 2017-2022
  • Rest of World Market for Life Sciences PCR, 2017-2022

The life science market for PCR grew steadily for over two decades, although this growth is leveling off now. This is a large, diverse market that is now facing competition from next generation sequencing for a number of applications.

PCR technology has been widely licensed to other companies for both life science (for the purposes of this report, the research market equals the life science market) and diagnostic applications, and many companies are now active in these fields. Real-time PCR (qPCR) has become the most widely used DNA amplification method today.

PCR was the first of what are now many nucleic acid amplification test (PCR) methods that have been developed and commercialized. Examples of isothermal PCRs include loop mediated isothermal amplification (LAMP), nicking enzyme amplification reaction (NEAR), strand displacement amplification (SDA), nucleic acid sequence based amplification (NASBA) and transcription-mediated amplification (TMA).

Isothermal PCRs have been developed that can provide results more quickly than qPCR, sometimes in less than 30 minutes. Reduced equipment requirements, simpler workflows and applicability to sample-to-answer platforms make isothermal methods ideal for decentralized and point-of-care molecular diagnostics. Both isothermal PCR and qPCR technologies are being applied to point-of-care and near-patient molecular diagnostics, opening up another new market for PCR-based tests.

Over time, many changes and improvements in PCR technology have been developed. One significant advance was the development of real-time PCR. With real-time PCR, detection of the amplicon occurs in real-time as the amplification reaction progresses, versus the initial PCR test technology method (traditional PCR), in which detection of amplified DNA product (amplicon) takes place at the end of the reaction (end-point PCR). Real-time PCR assays can be quantitative assays, measuring the initial number of copies of the target or template DNA that is present in a sample. Real-time PCR is typically referred to as qPCR, while the term “”RT-PCR”” is usually reserved for reverse transcriptase PCR, a method used to make a complementary DNA (cDNA) strand from RNA.

Digital PCR (dPCR) divides the reaction into smaller, discrete reactions, partitioning them so that individual nucleic acid molecules are localized and concentrated within numerous separate regions, be they in microplates, capillaries, arrays of miniaturized chambers, or water-oil emulsions (in a technique called droplet digital PCR, or ddPCR).

This report breaks out markets by both types of PCR.

Table of Contents

CHAPTER 1: EXECUTIVE SUMMARY

NUCLEIC ACID AMPLIFICATION TESTING OVERVIEW

 

SCOPE AND METHODOLOGY

 

MARKET OVERVIEW

Table 1-1: Life Science PCR Market, Instruments versus Consumables, Worldwide, 2016 and 2021 (in millions USD)

FUTURE PROSPECTS IN THE PCR MARKET

Figure 1-1: Life Sciences PCR Market Growth Picture by Country Region (US, Europe, Japan, China, LATAM,ROW)

CHAPTER 2: INTRODUCTION

DEVELOPMENT AND EVOLUTION OF POLYMERASE CHAIN REACTION AND OTHER NUCLEIC ACID AMPLIFICATION TESTS

 

Development and Evolution of PCR

 

Other Nucleic Acid Amplification Test Methods

 

Advances in Nucleic Acid Amplification Technology and Emerging Applications

 

POINT-OF-VIEW

CHAPTER 3: TECHNOLOGY TRENDS AND INNOVATION

 

POLYMERASE CHAIN REACTION (PCR) – OVERVIEW

 

PCR, RT-PCR, and qPCR

 

Digital PCR

 

Table 3-1: Selected Companies with Digital PCR Technology (For Research and/or Diagnostic Tests)

 

Multiplex PCR

 

Table 3-2: Selected Companies with Multiplex PCR Technology [Note: This is not a comprehensive list of all companies with multiplex PCR technology/tests.]

 

Other Modifications of PCR

 

Table 3-3: Selected Companies with Innovative PCR-Based Methods

OTHER NUCLEIC ACID AMPLIFICATION TEST (PCR) METHODS

Table 3-4: Companies with Other Nucleic Acid Amplification Test Methods

PLATFORMS USED IN DIFFERENT PCR MARKETS – RESEARCH, CLINICAL LABORATORIES, AND POINT-OF-CARE TESTING

Table 3-5: Selected Companies Marketing PCR Instruments/Reagents to the Life Sciences Market

NEW APPLICATIONS OF PCR – COMBINING PCR WITH OTHER TECHNOLOGIES

 

PCR Testing Market for Life Sciences

 

March 2018 © Kalorama ii Information

 

PCR as Part of Sample Prep before DNA Sequencing

 

Table 3-6: Examples of Companies Using PCR during Sample Prep before DNA Sequencing

 

CHAPTER 4: NUCLEIC ACID AMPLIFICATION TESTS IN RESEARCH

 

RESEARCH APPLICATIONS OF POLYMERASE CHAIN REACTION

 

NON-CLINICAL APPLICATIONS OF POLYMERASE CHAIN REACTION

 

CHAPTER 5: DEALS – POLYMERASE CHAIN REACTION/NUCLEIC ACID AMPLIFICATION TEST COMPANIES . 32

 

MERGERS AND ACQUISITIONS

Table 5-1: Selected Acquisitions of PCR Companies

 

CORPORATE AGREEMENTS AND COLLABORATIONS (NOT INCLUDING PHARMACEUTICAL COMPANIES)

 

Table 5-2: Selected Agreements between PCR Companies and Other Companies [Not Including

Pharmaceutical Companies]

 

COLLABORATIONS AND OTHER AGREEMENTS WITH UNIVERSITIES, NON-PROFIT RESEARCH INSTITUTES AND GOVERNMENT .. 59

Table 5-3: Selected PCR Company Agreements with Academic or Other Non-Profit Organizations

CHAPTER 6: MARKET DRIVERS AND CHALLENGES – NUCLEIC ACID AMPLIFICATION TEST MARKET

ISSUES AND HURDLES FACED BY PCR COMPANIES SELLING TO THE LIFE SCIENCE (RESEARCH) MARKET

 

COMPETITION FROM COMPANIES UTILIZING PCR AND OTHER PCR TECHNOLOGIES

 

COMPETITION AND MARKET OPPORTUNITIES DRIVEN BY OTHER (NON-PCR) TECHNOLOGIES

 

Competition

 

Opportunities

 

FUTURE PROSPECTS

Table 6-1: Trends in the Polymerase Chain Reaction/Nucleic Acid Amplification Test Market

CHAPTER 7: POLYMERASE CHAIN REACTION (PCR) AND NUCLEIC ACID AMPLIFICATION TEST (PCR)

MARKET ANALYSIS

 

NUCLEIC ACID AMPLIFICATION TEST MARKET OVERVIEW

 

Table 7-1: Life Science PCR Market (in millions USD)

 

LIFE SCIENCE PCR MARKET

 

Past and Future Growth of Overall Life Science PCR Market

 

Figure 7-1: Growth of the Life Science PCR Market (1990 – 2016) [# Abstracts Found per Year in PubMed search for “’polymerase chain

reaction’ or pcr”] (Accessed January 2018)

 

LIFE SCIENCE PCR MARKET – INSTRUMENTS VERSUS CONSUMABLES

 

Table 7-2: Life Science PCR Market, Instruments versus Consumables, Worldwide, 2016 and 2021 (in millions USD)

 

LIFE SCIENCE PCR MARKET – BY GEOGRAPHICAL DISTRIBUTION

 

The United States

 

Table 7-3: United States Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022

 

Europe

 

Table 7-4: European Market for Life Sciences PCR (Consumables, Instruments, Software/Service) , 2017-2022

Japan

Table 7-5: Japanese Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022

China

Table 7-6: Chinese Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022

LATAM

Table: 7-7: LATAM Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022

ROW

Table 7-8: ROW Market for Life Sciences PCR (Consumables, Instruments, Software/Service)

LIFE SCIENCE PCR MARKET BY TYPE OF PCR

dPCR

Table 7-9: dPCR Life Sciences Market, 2017-2022 (Consumables, Instruments, Software/Service)

qPCR

Table 7-10: qPCR Life Sciences Market, 2017-2022 (Consumables, Instruments, Software/Service)

LIFE SCIENCE PCR MARKET BY APPLICATION

General Medical/Disease Research

Table 7-11: General Medical/Disease Research (Consumables, Instruments, Software/Services)

Pharmaceutical Research

Table 7-12: Pharmaceutical Research (Consumables, Instruments, Software/Service), 2017-2022

CHAPTER 8: COMPANY PROFILES

AGENA BIOSCIENCE, INC.

 

AGILENT TECHNOLOGIES INC.

Recent Revenue History

Table 8-1: Agilent Technologies Revenues (2014, 2015, 2016, 2017)

Company Overview

AUTOGENOMICS, INC.

 

BIO-RAD LABORATORIES, INC

Recent Revenue History

Table 8-2: Bio-Rad Laboratories Net Sales (2014 to 2017)

Company Overview

 

BIOGENEX LABORATORIES, INC.

 

BIONEER CORPORATION

 

BJS BIOTEHCHNOLOGIES

 

BRUKER CORPORATION

Recent Revenue History

Table 8-3: Bruker Corporation Revenues (2014 – 2017)

Company Overview

 

COLE-PARMER (FORMERLY BIBBY SCIENTIFIC)

 

DENVILLE SCIENTIFIC, INC.

 

ENZO LIFE SCIENCES, INC.

Recent Revenue History

Table 8-4: Enzo Biochem, Inc. Revenues (FY2013 – FY2016)

Company Overview

EPPENDORF AG

Recent Revenue History

Table 8-5: Eppendorf AG Revenues (FY2014 – FY2016)

Company Overview

FLUIDIGM CORPORATION

 

INTEGRATED DNA TECHNOLOGIES, INC.

 

LGC DOUGLAS SCIENTIFIC

 

LUCIGEN CORPORATION

 

LUMINEX CORPORATION

 

Recent Revenue History

 

Table 8-6: Luminex Corporation Revenues (2014 – 2017)

 

Company Overview

 

PROMEGA CORPORATION

QIAGEN N.V.

 

Recent Revenue History

Table 8-7: QIAGEN Revenues (2014 – Q3 2017)

Company Overview

TAKARA BIO, INC.

Recent Revenue History

Table 8-8: Takara Bio Revenues (2014 – 2017)

Company Overview

THERMO FISHER SCIENTIFIC, INC.

Recent Revenue History

Table 8-9: Thermo Fisher Scientific Revenues (2014-2017)

Company Overview

 

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