Description
PCR Markets for Life Sciences Applications (Market by Type – qPCR, dPCR – Application – Pharmaceutical, General Research, and by Country and Region)
As part of its coverage of this market, Kalorama Information’s report provides:
- The Market for Life Sciences PCR, 2017 to 2022
- Application Market Segmentation of Pharmaceutical and General Medical Research
- Market Segmentation of qPCR and dPCR markets, 2017-2022
- United States Life Sciences PCR Market, 2017-2022
- European Life Sciences PCR Market, 2017-2022
- Japanese Market for Life Sciences PCR, 2017-2022
- China Market for Life Sciences PCR, 2017-2022
- LATAM Market for Life Sciences PCR, 2017-2022
- Rest of World Market for Life Sciences PCR, 2017-2022
The life science market for PCR grew steadily for over two decades, although this growth is leveling off now. This is a large, diverse market that is now facing competition from next generation sequencing for a number of applications.
PCR technology has been widely licensed to other companies for both life science (for the purposes of this report, the research market equals the life science market) and diagnostic applications, and many companies are now active in these fields. Real-time PCR (qPCR) has become the most widely used DNA amplification method today.
PCR was the first of what are now many nucleic acid amplification test (PCR) methods that have been developed and commercialized. Examples of isothermal PCRs include loop mediated isothermal amplification (LAMP), nicking enzyme amplification reaction (NEAR), strand displacement amplification (SDA), nucleic acid sequence based amplification (NASBA) and transcription-mediated amplification (TMA).
Isothermal PCRs have been developed that can provide results more quickly than qPCR, sometimes in less than 30 minutes. Reduced equipment requirements, simpler workflows and applicability to sample-to-answer platforms make isothermal methods ideal for decentralized and point-of-care molecular diagnostics. Both isothermal PCR and qPCR technologies are being applied to point-of-care and near-patient molecular diagnostics, opening up another new market for PCR-based tests.
Over time, many changes and improvements in PCR technology have been developed. One significant advance was the development of real-time PCR. With real-time PCR, detection of the amplicon occurs in real-time as the amplification reaction progresses, versus the initial PCR test technology method (traditional PCR), in which detection of amplified DNA product (amplicon) takes place at the end of the reaction (end-point PCR). Real-time PCR assays can be quantitative assays, measuring the initial number of copies of the target or template DNA that is present in a sample. Real-time PCR is typically referred to as qPCR, while the term “”RT-PCR”” is usually reserved for reverse transcriptase PCR, a method used to make a complementary DNA (cDNA) strand from RNA.
Digital PCR (dPCR) divides the reaction into smaller, discrete reactions, partitioning them so that individual nucleic acid molecules are localized and concentrated within numerous separate regions, be they in microplates, capillaries, arrays of miniaturized chambers, or water-oil emulsions (in a technique called droplet digital PCR, or ddPCR).
This report breaks out markets by both types of PCR.
Table of Contents
CHAPTER 1: EXECUTIVE SUMMARY
NUCLEIC ACID AMPLIFICATION TESTING OVERVIEW
SCOPE AND METHODOLOGY
MARKET OVERVIEW
Table 1-1: Life Science PCR Market, Instruments versus Consumables, Worldwide, 2016 and 2021 (in millions USD)
FUTURE PROSPECTS IN THE PCR MARKET
Figure 1-1: Life Sciences PCR Market Growth Picture by Country Region (US, Europe, Japan, China, LATAM,ROW)
CHAPTER 2: INTRODUCTION
DEVELOPMENT AND EVOLUTION OF POLYMERASE CHAIN REACTION AND OTHER NUCLEIC ACID AMPLIFICATION TESTS
Development and Evolution of PCR
Other Nucleic Acid Amplification Test Methods
Advances in Nucleic Acid Amplification Technology and Emerging Applications
POINT-OF-VIEW
CHAPTER 3: TECHNOLOGY TRENDS AND INNOVATION
POLYMERASE CHAIN REACTION (PCR) – OVERVIEW
PCR, RT-PCR, and qPCR
Digital PCR
Table 3-1: Selected Companies with Digital PCR Technology (For Research and/or Diagnostic Tests)
Multiplex PCR
Table 3-2: Selected Companies with Multiplex PCR Technology [Note: This is not a comprehensive list of all companies with multiplex PCR technology/tests.]
Other Modifications of PCR
Table 3-3: Selected Companies with Innovative PCR-Based Methods
OTHER NUCLEIC ACID AMPLIFICATION TEST (PCR) METHODS
Table 3-4: Companies with Other Nucleic Acid Amplification Test Methods
PLATFORMS USED IN DIFFERENT PCR MARKETS – RESEARCH, CLINICAL LABORATORIES, AND POINT-OF-CARE TESTING
Table 3-5: Selected Companies Marketing PCR Instruments/Reagents to the Life Sciences Market
NEW APPLICATIONS OF PCR – COMBINING PCR WITH OTHER TECHNOLOGIES
PCR Testing Market for Life Sciences
March 2018 © Kalorama ii Information
PCR as Part of Sample Prep before DNA Sequencing
Table 3-6: Examples of Companies Using PCR during Sample Prep before DNA Sequencing
CHAPTER 4: NUCLEIC ACID AMPLIFICATION TESTS IN RESEARCH
RESEARCH APPLICATIONS OF POLYMERASE CHAIN REACTION
NON-CLINICAL APPLICATIONS OF POLYMERASE CHAIN REACTION
CHAPTER 5: DEALS – POLYMERASE CHAIN REACTION/NUCLEIC ACID AMPLIFICATION TEST COMPANIES . 32
MERGERS AND ACQUISITIONS
Table 5-1: Selected Acquisitions of PCR Companies
CORPORATE AGREEMENTS AND COLLABORATIONS (NOT INCLUDING PHARMACEUTICAL COMPANIES)
Table 5-2: Selected Agreements between PCR Companies and Other Companies [Not Including
Pharmaceutical Companies]
COLLABORATIONS AND OTHER AGREEMENTS WITH UNIVERSITIES, NON-PROFIT RESEARCH INSTITUTES AND GOVERNMENT .. 59
Table 5-3: Selected PCR Company Agreements with Academic or Other Non-Profit Organizations
CHAPTER 6: MARKET DRIVERS AND CHALLENGES – NUCLEIC ACID AMPLIFICATION TEST MARKET
ISSUES AND HURDLES FACED BY PCR COMPANIES SELLING TO THE LIFE SCIENCE (RESEARCH) MARKET
COMPETITION FROM COMPANIES UTILIZING PCR AND OTHER PCR TECHNOLOGIES
COMPETITION AND MARKET OPPORTUNITIES DRIVEN BY OTHER (NON-PCR) TECHNOLOGIES
Competition
Opportunities
FUTURE PROSPECTS
Table 6-1: Trends in the Polymerase Chain Reaction/Nucleic Acid Amplification Test Market
CHAPTER 7: POLYMERASE CHAIN REACTION (PCR) AND NUCLEIC ACID AMPLIFICATION TEST (PCR)
MARKET ANALYSIS
NUCLEIC ACID AMPLIFICATION TEST MARKET OVERVIEW
Table 7-1: Life Science PCR Market (in millions USD)
LIFE SCIENCE PCR MARKET
Past and Future Growth of Overall Life Science PCR Market
Figure 7-1: Growth of the Life Science PCR Market (1990 – 2016) [# Abstracts Found per Year in PubMed search for “’polymerase chain
reaction’ or pcr”] (Accessed January 2018)
LIFE SCIENCE PCR MARKET – INSTRUMENTS VERSUS CONSUMABLES
Table 7-2: Life Science PCR Market, Instruments versus Consumables, Worldwide, 2016 and 2021 (in millions USD)
LIFE SCIENCE PCR MARKET – BY GEOGRAPHICAL DISTRIBUTION
The United States
Table 7-3: United States Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022
Europe
Table 7-4: European Market for Life Sciences PCR (Consumables, Instruments, Software/Service) , 2017-2022
Japan
Table 7-5: Japanese Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022
China
Table 7-6: Chinese Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022
LATAM
Table: 7-7: LATAM Market for Life Sciences PCR (Consumables, Instruments, Software/Service), 2017-2022
ROW
Table 7-8: ROW Market for Life Sciences PCR (Consumables, Instruments, Software/Service)
LIFE SCIENCE PCR MARKET BY TYPE OF PCR
dPCR
Table 7-9: dPCR Life Sciences Market, 2017-2022 (Consumables, Instruments, Software/Service)
qPCR
Table 7-10: qPCR Life Sciences Market, 2017-2022 (Consumables, Instruments, Software/Service)
LIFE SCIENCE PCR MARKET BY APPLICATION
General Medical/Disease Research
Table 7-11: General Medical/Disease Research (Consumables, Instruments, Software/Services)
Pharmaceutical Research
Table 7-12: Pharmaceutical Research (Consumables, Instruments, Software/Service), 2017-2022
CHAPTER 8: COMPANY PROFILES
AGENA BIOSCIENCE, INC.
AGILENT TECHNOLOGIES INC.
Recent Revenue History
Table 8-1: Agilent Technologies Revenues (2014, 2015, 2016, 2017)
Company Overview
AUTOGENOMICS, INC.
BIO-RAD LABORATORIES, INC
Recent Revenue History
Table 8-2: Bio-Rad Laboratories Net Sales (2014 to 2017)
Company Overview
BIOGENEX LABORATORIES, INC.
BIONEER CORPORATION
BJS BIOTEHCHNOLOGIES
BRUKER CORPORATION
Recent Revenue History
Table 8-3: Bruker Corporation Revenues (2014 – 2017)
Company Overview
COLE-PARMER (FORMERLY BIBBY SCIENTIFIC)
DENVILLE SCIENTIFIC, INC.
ENZO LIFE SCIENCES, INC.
Recent Revenue History
Table 8-4: Enzo Biochem, Inc. Revenues (FY2013 – FY2016)
Company Overview
EPPENDORF AG
Recent Revenue History
Table 8-5: Eppendorf AG Revenues (FY2014 – FY2016)
Company Overview
FLUIDIGM CORPORATION
INTEGRATED DNA TECHNOLOGIES, INC.
LGC DOUGLAS SCIENTIFIC
LUCIGEN CORPORATION
LUMINEX CORPORATION
Recent Revenue History
Table 8-6: Luminex Corporation Revenues (2014 – 2017)
Company Overview
PROMEGA CORPORATION
QIAGEN N.V.
Recent Revenue History
Table 8-7: QIAGEN Revenues (2014 – Q3 2017)
Company Overview
TAKARA BIO, INC.
Recent Revenue History
Table 8-8: Takara Bio Revenues (2014 – 2017)
Company Overview
THERMO FISHER SCIENTIFIC, INC.
Recent Revenue History
Table 8-9: Thermo Fisher Scientific Revenues (2014-2017)
Company Overview
